(n.) A pill or bolus for introduction into the rectum; esp., a cylinder or cone of medicated cacao butter.
Example Sentences:
(1) Diclofenac sodium suppositories 150-200 mg day-1 were compared with placebo in a double-blind study during the first 3 days after uvulopalatopharyngoplasty in 40 patients with habitual snoring or obstructive sleep apnoea syndrome.
(2) The in vitro and in vivo results show that the release of indomethacin from fatty-base suppositories stored at a high temperature is less than the release from those stored at a low temperature.
(3) After liberation of 5-ASA in the terminal ileum (only slow release oral preparations of 5-ASA) and colon (5-ASA suppositories and enemas), 5-ASA is only partly absorbed.
(4) Rectal suppository is a well-known form of medication and its use is increasing.
(5) The administration of PGE2 vaginal suppositories offers an effective and safe technique for the induction of labor in patients with IUFD.
(6) The absorption times of the two drugs from suppositories with cocoa butter and Witepsol H 15 were relatively short.
(7) In vitro release of benzocaine from some commercially available suppositories was compared with experimental preparations.
(8) The adsorption in humans of nitrofurantoin from seven suppository bases was studied using urinary excretion measurements.
(9) The results show that both hydrocortisone (H) and prednisolone-21-hexanoate (P) are rapidly (tmax = 2-3 h) and significantly (H: 60-78%, P: 47-58%) absorbed from suppositories and thus can also cause systemic effects.
(10) Three cases of adenocarcinoma of the lower esophagus and cardia which is considered to be difficult to control by radiotherapy alone, were given radical irradiation combined with FT-207 suppository.
(11) In volunteers the activity of various doses of a nasal spray and of a suppository of salmon calcitonin was compared to a placebo and to the parenteral route of administration.
(12) When vomiting occurs early in the attack, treatment is best given by suppository, inhalation or intramuscular injection.
(13) Primary eye irritation of MCG suppository of CMZ was studied in rabbits.
(14) Treatment consisted of daily intravaginal application of one of the following regimens: 80-mg terconazole suppositories for 3 days, miconazole nitrate suppositories for 7 days or placebo suppositories for 7 days.
(15) Further studies in pregnant women showed that PGE2 administered in special vaginal suppositories resulted in: 1) 1 case at the 23rd week of pregnancy, the expulsion of the dead fetus by inserting 2 suppositories (4 mg PGE2 each) with the induction delivery time of 2 hours 20 minutes, and 2) one case in which the expulsion occurred after 1 suppository with an induction delivery time of 4 hours 30 minutes.
(16) We were enlightened by this therapeutic experience, so we attempted combination therapy using pepleomycin suppositories to supplement intra-cavitary irradiation, for the 11 selected patients who were suffering from uterine fluor.
(17) Oral administration gave higher values for mean residence time (MRT) and absolute bioavailability (F) compared to suppository dosage forms.
(18) 1 group (non-diaphragm) had a 20 mg. suppository inserted every 4 hours high in the vaginal fornix.
(19) Patients were divided into three treatment groups: one group received the drug intravenously, another as suppositories and the third one by both routes.
(20) The women were all 9 weeks pregnant, and received 600 mg RU-38486 orally at 10.30 hr, followed 48 hours later by a vaginal suppository containing 1 mg 16,16- dimethyl-trans-2-PGE1 (Gemeprost, May and Baker).
Urethra
Definition:
(n.) The canal by which the urine is conducted from the bladder and discharged.
Example Sentences:
(1) In one of them, who sustained a complete membranous disruption 5 weeks ago, transluminal puncture failed because of the movable proximal urethra.
(2) In 36 patients plastic reconstruction of the urinary bladder, sphincter and urethra was performed with local tissues after the Young technic in the G. A. Bairov modification.
(3) Manual compression of the bladder elicited urine leakage from the urethra, and the urethral closure pressure was markedly low.
(4) The acrosin inhibitors are localized in the mucosa cells of the cauda epididymis, the vas deferens, the seminal vesicles, the urethra and distinct glandular units of the prostate.
(5) During unstable detrusor contractions, which even in these healthy women are observed during bladder filling and also during inhibited voidings through the urethra, the contraction is weaker.
(6) We concluded that this case was incidentally successful with good regeneration of urethral mucosa of the anterior urethra by grafting a polytetrafluoroethylene tube.
(7) All the examinees showed no organic changes in the prostate and urethra.
(8) The results are not simply explained by postulating electrically induced closure of the urethra.
(9) Spinning top urethra (STU) is a term used to describe a widened posterior urethra seen mainly in girls.
(10) The dysfunction is due partly to direct trauma of the bladder and urethra.
(11) The two halves of the glans are brought to the midline, thus covering the glanular urethra, and producing a normal appearing glans.
(12) The relaxation effects of prazosin and bunazosin on the distal urethra was weaker than on the proximal urethra.
(13) The majority were investigated at the bedside by taking films and cultures from the cervix and urethra.
(14) After rhizotomy, noradrenaline content in the proximal urethra was significantly increased but there was no change in sensitivity to sympathetic stimulation.
(15) Partial resection of anterior urethra including tumor was performed on December 20, 1983.
(16) This surgical procedure involves removing the penile urethra and creating a permanent stoma between the skin and pelvic urethra.
(17) In 20-35 per cent of short (up to 05 cm) urethral stenosis or cicatricial obliterations of urethra it was found advisable to start the treatment with nonoperative technique.
(18) The sphincter urethrae muscle is located inside the sling of the puborectalis muscle in both sexes, but no muscle fibres connect them to one another.
(19) The complication rate was astonishingly low during IUSC: being only 4.3% (2 male patients, one with stricture of the urethra and epididymitis, one with autonomous dysreflexia with bladder overdistension).
(20) The results appear to offer pharmacological evidence for the recently evolving intricate innervation pattern of the urethra including its distal portion, where the alpha-adrenergic system is believed to be important.