(n.) Composition, or the putting of two or more things together, as in compounding medicines.
(n.) The art or process of making a compound by putting the ingredients together, as contrasted with analysis; thus, water is made by synthesis from hydrogen and oxygen; hence, specifically, the building up of complex compounds by special reactions, whereby their component radicals are so grouped that the resulting substances are identical in every respect with the natural articles when such occur; thus, artificial alcohol, urea, indigo blue, alizarin, etc., are made by synthesis.
(n.) The combination of separate elements of thought into a whole, as of simple into complex conceptions, species into genera, individual propositions into systems; -- the opposite of analysis.
Example Sentences:
(1) Synthesis of choline esterase on the medium with acetylcholine at a concentration of 1% was increased more than twofold upon addition of glucose at a concentration of 0.1%.
(2) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(3) alpha 1-Adrenergic agonists, phenylephrine and norfenefrine, did not affect the synthesis.
(4) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(5) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(6) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(7) In addition to oncogenes, the transferred DNA contains genes that direct the synthesis and exudation of opines, which are used as nutrients by the bacteria.
(8) dl-Methionine stimulated the synthesis of cephalosporins when added after the growth phase.
(9) When the data correlating DHT with protein synthesis using both labelling techniques were combined, the curves were parallel and a strong correlation was noted between DHT and protein synthesis over a wide range of values (P less than 0.001).
(10) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(11) MAF-G activity was inhibited by mitomycin C and colchicine, which inhibit DNA synthesis and mitosis, respectively, but not by 2-deoxy-D-glucose, an inhibitor of glucose metabolism.
(12) However, both were identical in size when synthesized in COS-1 cells in the presence of tunicamycin or when deglycosylated after their synthesis in Xenopus oocytes.
(13) The blockade of H2 receptors is the primary action of these drugs; however, they possess also secondary actions which may represent untoward effects but in some cases may be actually useful (increase in prostaglandin synthesis, inhibition of LTB4 synthesis, etc.)
(14) The amino-terminal region of a 70 kDa mitochondrial outer membrane protein of yeast and the presequence of cytochrome c1, an inner membrane protein exposed to the intermembrane space, are thought to be responsible for localizing the proteins in their final destinations after synthesis in the cytosol.
(15) During the 1st h after induction of the sporulation process, the rate of protein synthesis increased to two times the initial value.
(16) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(17) Moreover, the data showed for the first time that DNA synthesis in the bone marrow and spleen and colon were markedly statistically significantly stimulated at specific times after treatment.
(18) Hyperimmunization with the tick encephalitis and Western horse encephalomyelitis viruses reproduced in the brain of albino mice, intensified the protein synthesis in the splenic tissue during the productive phase of the immunogenesis (the 7th day).
(19) The ability of cytoplasmic extracts to induce DNA synthesis in isolated, quiescent nuclei.
(20) With the stimulated liver being irradiated, the number of cells synthetizing DNA and entering into mitosis was seen reduced almost twice, whereas DNA synthesis and entering into mitosis were delayed, resp., by 4 and 6 hours.
Urethane
Definition:
(n.) A white crystalline substance, NH2.CO.OC2H5, produced by the action of ammonia on ethyl carbonate. It is used somewhat in medicine as a hypnotic. By extension, any one of the series of related substances of which urethane proper is the type.
Example Sentences:
(1) In urethane-anesthetized rabbits, IOP and blood pressure were lowered by intravenous administration of delta 9-THC but not by bolus cerebral administration.
(2) Chloralose-urethane is considered a suitable anaesthetic in rats when studying the effects of noradrenaline and guanethidine.
(3) Experiments were carried out under urethane anaesthesia.
(4) Urethane also produced a trend towards metabolic acidosis.
(5) Differential pulse voltammetry used in combination with an electrochemically treated carbon fiber electrode allowed the detection of 5-hydroxyindoles (5-HI) in the dorsal horn of the urethane-anesthetized rat.
(6) Seven or 14 days of treatment with the beta 2-adrenoceptor agonist clenbuterol, 0.3 mg kg-1, s.c., twice daily, increased the basal mean blood pressure in normotensive urethane-anaesthetized rats.
(7) To try to compare receptor compartment kinetics, receptor binding, and binding-response coupling for two smooth muscle types in vivo, pressor and uterine responses to oxypressin, an equipotent analog of oxytocin and vasopressin, were studied simultaneously in urethane-anesthetized, pentolinium-indomethacin treated rats.
(8) Single unit discharges in the ventromedial hypothalamic nucleus (VMH) and lateral hypothalamic area (LH) were extracellularly recorded in urethane anesthetised female rats, while various solutions were perfused through the stomach or duodenum via implanted polythene tubes.
(9) The role of the sympatho-adrenal system in the production of tachycardia accompanying the hypotensive response to hydralazine was studied in urethane-anesthetized rats subjected to previous bilateral adrenal demedullation or to pretreatment with 6-hydroxydopamine and compared with intact control animals.
(10) A germ line mutation causing a tumour ('tumour mutation') is weakly carcinogenic by itself, but it is strongly expressed in the progeny after postnatal treatment with a small dose of the carcinogenesis promoting agent urethane.
(11) Experiments were carried out on 36 urethane-chloralose aneasthesized, paralyzed, vagotomized and artificially ventilated rabbits.
(12) Fasting hyperglycemia was observed in urethane-anesthetized rats.
(13) Much evidence now exists which defines the ability of poly(ether)urethanes to selectively extract ions, especially calcium ion from solution.
(14) Filling of the gastric lumen of rats with 1.0 M NaCl solution (5 ml) for 10 min under urethane anesthesia caused an increase in the gastric fluid concentrations of prostaglandin (PG) E2, 13,14-dihydro-15-keto-PGE2 and 6-keto-PGF1 alpha as determined by radioimmunoassay.
(15) The effect of thyrotropin-releasing hormone (TRH) on the mechanism regulating growth hormone (GH) secretion was investigated in urethane-anesthetized male rats.
(16) In urethane-anesthetized rats, low frequency electrical stimulation of the thalamic radiation (TR) evoked an augmenting response in the somatosensory cortex (SCx) which was followed by rhythmic slow waves.
(17) The frequencies of transformations of primary human and Chinese hamster fibroblasts have been compared with the spontaneous and induced frequencies of mutation for resistance to thioguanine and ouabain, and for ability to use fructose, using the carcinogens benzo (alpha) pyrene and urethane.
(18) In urethane-anaesthetized rats clonidine was administered intravenously (i.v.
(19) One end of the spacer group was coupled to the derivatized surface through a urethane bond between the amine group of the spacer and the derivatized surface.
(20) These compounds were tested for anticarcinogenic activity against urethane-induced pulmonary adenomas and for antitumoral activity against some transplanted tumours such as leukemia L 1210, mammary adenocarcinoma Ca 755 and Walker carcinosarcoma 256.