(n.) The act of terminating, or of limiting or setting bounds; the act of ending or concluding; as, a voluntary termination of hostilities.
(n.) That which ends or bounds; limit in space or extent; bound; end; as, the termination of a line.
(n.) End in time or existence; as, the termination of the year, or of life; the termination of happiness.
(n.) End; conclusion; result.
(n.) Last purpose of design.
(n.) A word; a term.
(n.) The ending of a word; a final syllable or letter; the part added to a stem in inflection.
Example Sentences:
(1) The amino acid sequence deduced from the nucleotide sequence contained both amino- and carboxyl-terminal sequences.
(2) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(3) We have examined the insertion of bovine 17 alpha-hydroxylase (P45017 alpha) into the endoplasmic reticulum of COS 1 cells to evaluate the functional role of its hydrophobic amino-terminal sequence and membrane insertion.
(4) The use of glucagon in double-contrast studies of the colon has been recommended for various reasons, one of which is to facilitate reflux of barium into the terminal ileum.
(5) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
(6) Plasma NPY correlated better with plasma norepinephrine than with epinephrine, indicating its origin from sympathetic nerve terminals.
(7) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(8) In the caudal spinal trigeminal nucleus (Vc), the collaterals of one half of the periodontium afferent fibers terminated mainly in lamina V at the rostral and middle levels of Vc.
(9) The amino-terminal region of a 70 kDa mitochondrial outer membrane protein of yeast and the presequence of cytochrome c1, an inner membrane protein exposed to the intermembrane space, are thought to be responsible for localizing the proteins in their final destinations after synthesis in the cytosol.
(10) The mtRF-1 could translate all of the known termination codons in the rat mitochondrial genome.
(11) However, none of the nerve terminals making synaptic contacts with glomus cells exhibited SP-like immunoreactivity.
(12) The B cell epitopes included regions of transition between the more hydropathic (including the N-terminal end of the F1 and F2 protein) and hydrophilic sequences.
(13) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
(14) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(15) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(16) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(17) The earliest degenerative changes were seen in sensory and motor terminals at 20-24 h after the lesion.
(18) The terminal half-life averaged 12 h following intravenous and 15 h after oral administration.
(19) A retrospective study examined the reactions to the termination of pregnancy for fetal malformation and the follow up services that were available.
(20) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
Truncation
Definition:
(n.) The act of truncating, lopping, or cutting off.
(n.) The state of being truncated.
(n.) The replacement of an edge or solid angle by a plane, especially when the plane is equally inclined to the adjoining faces.
Example Sentences:
(1) The relative potencies compared to insulin-like growth factor 2 (IGF-2) in displacing [125I]IGF-2 from rat liver membranes were recombinant truncated IGF-1, 0.3% and recombinant IGF-1, 0.2%.
(2) When the transcriptional activity of these proteins was examined it was found that carboxyl-truncated Myb is more effective as a transcriptional activator than full-length or amino-truncated Myb.
(3) The vector is relatively small (6 kilobase pairs) and contains a portion of the L. seymouri alpha-tubulin gene positioned in-frame with a truncated neomycin phosphotransferase gene that confers resistance to the aminoglycoside G418.
(4) These plasmids allow expression of native or truncated forms of the enzyme and easy purification of the products.
(5) Both the intracellular and secreted forms of the mu chains were similarly truncated.
(6) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(7) The other chimeras accumulated in the plasma membrane, and truncated LEP100 was secreted.
(8) The main protein species produced from full-length and truncated forms of celE was around 40 kDa in size and had an N-terminal amino acid sequence corresponding to that derived for mature EGE from the nucleotide sequence; in addition, larger species of about 75 kDa, presumably corresponding to full-size EGE, were produced by E. coli containing the full-length celE gene.
(9) The truncated LuxR proteins showed little or no ability to activate transcription of luxICDABE, as indicated by using luminescence as a sensitive indicator of promoter strength in E. coli.
(10) The expression of keratin and differentiation markers was identical to that of normal keratinocytes, suggesting that psoriatic epidermal differentiation is not truncated in vitro as has been postulated to be the case in vivo.
(11) Actin also exhibited a clear dual wave pattern of transport that coincided well with that of tubulin, indicating that both actin and tubulin were the major components of both groups IV and V.(ABSTRACT TRUNCATED AT 250 WORDS)
(12) This truncated C8C8 ceramide was soluble in water (but was still able to cross cell membranes) and was utilized by the Golgi apparatus of living cells to produce water-soluble truncated phospholipids and glycolipids that were then secreted into the medium.
(13) Neither the source nor the role of this soluble, truncated form of the membrane receptor has been determined.
(14) It may differ from the Mr 35,000 form in glycosylation or carboxyl-terminal truncation.
(15) The low hormone binding affinities of the truncated receptors taken together with high affinity hormone binding to the N-terminal extension of the LH receptor indicate the existence of two or more contact points between the receptor and the hormone.
(16) We were unable to confirm the high frequency of truncated messages of 4.7R in RB tumors reported by Lee et al.
(17) A transformed cell line containing a truncated gag-abl-pol protein, p85, that lacks most of the FeLV pol sequences was obtained by transfection of NIH 3T3 mouse cells.
(18) The calmodulin-binding domain of the CYA 62 truncated enzyme was labeled with a cleavable radioactive photoaffinity cross-linker coupled to calmodulin.
(19) This truncated receptor, lacking a transmembrane domain, appears not to be expressed at the plasma membrane.
(20) A truncated anchor-minus form of the G2 glycoprotein was found to be secreted into the culture medium, but was retained in the Golgi complex when coexpressed with the G1 glycoprotein.