(n.) The Roman divinity who presided over boundaries, whose statue was properly a short pillar terminating in the bust of a man, woman, satyr, or the like, but often merely a post or stone stuck in the ground on a boundary line.
(n.) Hence, any post or stone marking a boundary; a term. See Term, 8.
(n.) Either end of a railroad line; also, the station house, or the town or city, at that place.
Example Sentences:
(1) Conditions for limited digestion of the heterodimer by subtilisin, removing only the carboxyl terminus, were determined.
(2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
(3) Synthetic DNA corresponding to the hydrophobic domain of cytochrome b5 was enzymatically fused in-frame to cloned DNA corresponding to the C-terminus of the Escherichia coli enzyme, beta-galactosidase.
(4) TCR beta chain gene expression of individual T cell clones that share the same MHC class II restriction and similar fine specificity for the encephalitogenic NH2 terminus of the autoantigen myelin basic protein (MBP) has been examined.
(5) When these sequences were fused to the N terminus of yeast cytochrome oxidase subunit IV lacking its own presequence, they directed the attached subunit IV to its correct intramitochondrial location in vivo.
(6) Both proteins appeared to be recognized by antibodies against the amino (N) terminus of the alpha 1 subunit sequence.
(7) These plasmin-cleaved peptides are derived from the COOH terminus of C2b, and they induce the contraction of estrous rat uterus.
(8) From the decreased alignment at the N-terminus and the presence of additional residues compared with bacterial phosphorylases, we conclude that the regulatory sequences that also carry the phosphorylation site in the muscle enzyme were joined to a presumed ancestral precursor gene by gene fusion after separation of the eukaryotic and prokaryotic lines of descent.
(9) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
(10) The N-terminal sequence (15 amino acid residues) of the L-proline activating fragment obtained by trypsin treatment was identical with that of GS2, indicating that the L-proline activating site is located at the N-terminus of the native synthetase.
(11) It is suggested that a general manner of folding may be a common feature of the heterogeneous population of kappa-chains: one bridge which folds an invariable stretch of the chain, another bridge which folds a stretch that varies from protein to protein, and a bridge at the C-terminus which is the interchain link.
(12) Cysteine proteinase I cleaved peptides primarily from the C-terminal region of Tg, which contained two major hormonogenic sites, while cathepsin-B produced peptides mainly from the N-terminus, containing another major hormonogenic site.
(13) Deletions from the N terminus of LMM did not alter the solubility properties of the expressed material, but deletion of 92 residues from the C terminus caused a large increase in solubility at low ionic strength, indicating that a determinant important for interaction between LMM molecules was located in this region.
(14) Middle component particles of bean pod mottle virus (BPMV) containing small protein subunits with a cleaved C terminus were used to produce monoclonal antibodies (MAbs).
(15) We find that the NH2-terminus of PTH is rapidly degraded in situ by the liver but that both liver and especially kidney nevertheless contain low levels of NH2-terminal PTH fragments that, although not released into the blood, are large enough to be potentially active.
(16) 2) By contrast, the COOH terminus is an inhibitory regulator of mitogenesis, and removal of the terminal 43 amino acids converts the receptor from a moderately active growth signaler to a very active one.
(17) Since the HPV-16 E6-promoted degradation involves the ubiquitin-dependent proteolysis pathway, specific mutations were made in the amino terminus of p53 to examine whether the E6 targeted degradation involved the N-end rule pathway.
(18) Examination of the inhibitory effect of ATP using oligo(dA)12-18 as well as activated DNA as primers revealed that (a) ATP inhibition is not due to its addition onto a 3'-OH primer terminus ad judged by the lack of incorporation of labeled ATP, although under similar conditions incorporation of GTP can be demonstrated, (b) a consistent degree of inhibition was noted independent of primer or enzyme concentration; (c) addition of ATP to an ongoing reaction promptly reduces the rate of polymerization; (d) kinetic studies indicate a competitive (with respect to substrate deoxy triphosphate) pattern of inhibition; (e) addition of excess deoxyribotriphosphate promptly relieves the inhibition.
(19) A peptide corresponding to the COOH terminus (residues 45-65) was synthesized utilizing lysine 47 as a specific residue to conjugate to thyroglobulin as a carrier for raising antibodies in mice.
(20) Myristic acid-labeled virions contained a single radioactive protein, p10, supporting the mapping of this molecule to the amino terminus.
Town
Definition:
(adv. & prep.) Formerly: (a) An inclosure which surrounded the mere homestead or dwelling of the lord of the manor. [Obs.] (b) The whole of the land which constituted the domain. [Obs.] (c) A collection of houses inclosed by fences or walls.
(adv. & prep.) Any number or collection of houses to which belongs a regular market, and which is not a city or the see of a bishop.
(adv. & prep.) Any collection of houses larger than a village, and not incorporated as a city; also, loosely, any large, closely populated place, whether incorporated or not, in distinction from the country, or from rural communities.
(adv. & prep.) The body of inhabitants resident in a town; as, the town voted to send two representatives to the legislature; the town voted to lay a tax for repairing the highways.
(adv. & prep.) A township; the whole territory within certain limits, less than those of a country.
(adv. & prep.) The court end of London;-- commonly with the.
(adv. & prep.) The metropolis or its inhabitants; as, in winter the gentleman lives in town; in summer, in the country.
(adv. & prep.) A farm or farmstead; also, a court or farmyard.
Example Sentences:
(1) For some time now, public opinion polls have revealed Americans' strong preference to live in comparatively small cities, towns, and rural areas rather than in large cities.
(2) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(3) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(4) He had been just asked to open their new town hall, in the hope he might donate a Shakespeare statue.
(5) Nearly four months into the conflict, rebels control large parts of eastern Libya , the coastal city of Misrata, and a string of towns in the western mountains, near the border with Tunisia.
(6) The case was tried in a town called St Francisville, the closest courthouse to Angola.
(7) The autopsy findings in 41 patients with University of Cape Town aortic valve prostheses were studied.
(8) It will act as a further disincentive for women to seek help.” When Background Briefing visited Catherine Haven in February, the refuge looked deserted, and most of its rooms were empty, despite the town having one of the highest domestic violence rates in the state.
(9) He said: "This is a wonderful town but Tesco will suck the life out of the greengrocers, butchers, off-licence, and then it is only a matter of time for us too.
(10) Conservative commentators responded with fury to what they believed was inappropriate meddling at a crucial moment in the town hall debate.
(11) The article reflects the experience in the work of the manual therapy consulting-room at the Smela town hospital named after N. A. Semashko in Chernigov Province from November 1985 to December 1987 inclusive.
(12) In October, an episode of South Park saw the whole town go gluten-free (the stuff, it was discovered, made one’s penis fly off).
(13) But no one was sure, and in this information vacuum the virus reached nearby towns and crossed borders.
(14) But last year Rosi Santoni, one of the relatives who helped look after her, said she had plenty of family to care for her and had many friends in the town.
(15) He wound up repossessing the cars of workers who fled town after the bust.
(16) It was shown that: although the oral hygiene level was very low and no dental treatments were performed, caries level was very low--although gingivitis rate was high, advanced periodontitis rate was low--the frequency of interincisive diastema (one subject out of 4 in the 15-19 age group), the progressive decline of tooth cutting, a traditional practice, in town people but the large extent of cola use (one adult out of two).
(17) "There were around 50 attackers, heavily armed in three vehicles, and they were flying the Shebab flag," Maisori added, speaking from the town, where several buildings including hotels, restaurants, banks and government offices were razed to the ground.
(18) Referee: Peter Bankes (Merseyside) This gnome, who lives in the shrubbery of Guardian gardening expert Jane Perrone, will be rooting for Luton Town this afternoon.
(19) Barbacoas is a small port town in south-west Colombia, which linked the southern regions of the country in the 19th and 20th century.
(20) In 2013, the town’s municipal court generated $221,164 (or $387 for each of its residents), with much of the fees coming from ticketing non-residents.