What's the difference between terminus and up?

Terminus


Definition:

  • (n.) Literally, a boundary; a border; a limit.
  • (n.) The Roman divinity who presided over boundaries, whose statue was properly a short pillar terminating in the bust of a man, woman, satyr, or the like, but often merely a post or stone stuck in the ground on a boundary line.
  • (n.) Hence, any post or stone marking a boundary; a term. See Term, 8.
  • (n.) Either end of a railroad line; also, the station house, or the town or city, at that place.

Example Sentences:

  • (1) Conditions for limited digestion of the heterodimer by subtilisin, removing only the carboxyl terminus, were determined.
  • (2) The elongation of helix III with the addition of helix II at the N-terminus somewhat stabilizes the ordered structure.
  • (3) Synthetic DNA corresponding to the hydrophobic domain of cytochrome b5 was enzymatically fused in-frame to cloned DNA corresponding to the C-terminus of the Escherichia coli enzyme, beta-galactosidase.
  • (4) TCR beta chain gene expression of individual T cell clones that share the same MHC class II restriction and similar fine specificity for the encephalitogenic NH2 terminus of the autoantigen myelin basic protein (MBP) has been examined.
  • (5) When these sequences were fused to the N terminus of yeast cytochrome oxidase subunit IV lacking its own presequence, they directed the attached subunit IV to its correct intramitochondrial location in vivo.
  • (6) Both proteins appeared to be recognized by antibodies against the amino (N) terminus of the alpha 1 subunit sequence.
  • (7) These plasmin-cleaved peptides are derived from the COOH terminus of C2b, and they induce the contraction of estrous rat uterus.
  • (8) From the decreased alignment at the N-terminus and the presence of additional residues compared with bacterial phosphorylases, we conclude that the regulatory sequences that also carry the phosphorylation site in the muscle enzyme were joined to a presumed ancestral precursor gene by gene fusion after separation of the eukaryotic and prokaryotic lines of descent.
  • (9) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
  • (10) The N-terminal sequence (15 amino acid residues) of the L-proline activating fragment obtained by trypsin treatment was identical with that of GS2, indicating that the L-proline activating site is located at the N-terminus of the native synthetase.
  • (11) It is suggested that a general manner of folding may be a common feature of the heterogeneous population of kappa-chains: one bridge which folds an invariable stretch of the chain, another bridge which folds a stretch that varies from protein to protein, and a bridge at the C-terminus which is the interchain link.
  • (12) Cysteine proteinase I cleaved peptides primarily from the C-terminal region of Tg, which contained two major hormonogenic sites, while cathepsin-B produced peptides mainly from the N-terminus, containing another major hormonogenic site.
  • (13) Deletions from the N terminus of LMM did not alter the solubility properties of the expressed material, but deletion of 92 residues from the C terminus caused a large increase in solubility at low ionic strength, indicating that a determinant important for interaction between LMM molecules was located in this region.
  • (14) Middle component particles of bean pod mottle virus (BPMV) containing small protein subunits with a cleaved C terminus were used to produce monoclonal antibodies (MAbs).
  • (15) We find that the NH2-terminus of PTH is rapidly degraded in situ by the liver but that both liver and especially kidney nevertheless contain low levels of NH2-terminal PTH fragments that, although not released into the blood, are large enough to be potentially active.
  • (16) 2) By contrast, the COOH terminus is an inhibitory regulator of mitogenesis, and removal of the terminal 43 amino acids converts the receptor from a moderately active growth signaler to a very active one.
  • (17) Since the HPV-16 E6-promoted degradation involves the ubiquitin-dependent proteolysis pathway, specific mutations were made in the amino terminus of p53 to examine whether the E6 targeted degradation involved the N-end rule pathway.
  • (18) Examination of the inhibitory effect of ATP using oligo(dA)12-18 as well as activated DNA as primers revealed that (a) ATP inhibition is not due to its addition onto a 3'-OH primer terminus ad judged by the lack of incorporation of labeled ATP, although under similar conditions incorporation of GTP can be demonstrated, (b) a consistent degree of inhibition was noted independent of primer or enzyme concentration; (c) addition of ATP to an ongoing reaction promptly reduces the rate of polymerization; (d) kinetic studies indicate a competitive (with respect to substrate deoxy triphosphate) pattern of inhibition; (e) addition of excess deoxyribotriphosphate promptly relieves the inhibition.
  • (19) A peptide corresponding to the COOH terminus (residues 45-65) was synthesized utilizing lysine 47 as a specific residue to conjugate to thyroglobulin as a carrier for raising antibodies in mice.
  • (20) Myristic acid-labeled virions contained a single radioactive protein, p10, supporting the mapping of this molecule to the amino terminus.

Up


Definition:

  • (adv.) Aloft; on high; in a direction contrary to that of gravity; toward or in a higher place or position; above; -- the opposite of down.
  • (adv.) From a lower to a higher position, literally or figuratively; as, from a recumbent or sitting position; from the mouth, toward the source, of a river; from a dependent or inferior condition; from concealment; from younger age; from a quiet state, or the like; -- used with verbs of motion expressed or implied.
  • (adv.) In a higher place or position, literally or figuratively; in the state of having arisen; in an upright, or nearly upright, position; standing; mounted on a horse; in a condition of elevation, prominence, advance, proficiency, excitement, insurrection, or the like; -- used with verbs of rest, situation, condition, and the like; as, to be up on a hill; the lid of the box was up; prices are up.
  • (adv.) To or in a position of equal advance or equality; not short of, back of, less advanced than, away from, or the like; -- usually followed by to or with; as, to be up to the chin in water; to come up with one's companions; to come up with the enemy; to live up to engagements.
  • (adv.) To or in a state of completion; completely; wholly; quite; as, in the phrases to eat up; to drink up; to burn up; to sum up; etc.; to shut up the eyes or the mouth; to sew up a rent.
  • (adv.) Aside, so as not to be in use; as, to lay up riches; put up your weapons.
  • (prep.) From a lower to a higher place on, upon, or along; at a higher situation upon; at the top of.
  • (prep.) From the coast towards the interior of, as a country; from the mouth towards the source of, as a stream; as, to journey up the country; to sail up the Hudson.
  • (prep.) Upon.
  • (n.) The state of being up or above; a state of elevation, prosperity, or the like; -- rarely occurring except in the phrase ups and downs.
  • (a.) Inclining up; tending or going up; upward; as, an up look; an up grade; the up train.

Example Sentences: