(1) Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
(2) The expression of the mRNA for mouse testicular lactate dehydrogenase (LDH-X) was examined by RNA:cDNA hybridization in situ in the testis and by Northern analyses of meiotic and postmeiotic spermatogenic cell populations.
(3) In contrast, Leydig cells from rat testis contain monooxygenase systems which catalyze the metabolism of PAH, such as DMBA.
(4) Testis MAPs promoted microtubule assembly, but to a lesser degree than brain MAPs.
(5) Comparison of the native and derivatized wheat germ CaMs with native bovine testis CaM indicates that the concentrations of these proteins required for half-maximal stimulation of either erythrocyte membrane Ca2+-ATPase activity or cardiac sarcoplasmic reticulum phosphorylation are very similar.
(6) In an effort to understand the regulation of the onset of testosterone formation in the human fetal testis we measured adenylate cyclase activity in response to hCG stimulation in homogenates of fetal testes obtained from first and second trimester human abortuses.
(7) Gonadoblastoma is an unusual tumor that typically arises in a streak gonad or an abnormal testis of an individual having a Y chromosome.
(8) Immune response in a patient with an in-situ seminoma of the testis was studied.
(9) We conclude that there are high levels of a GHRH-like substance in mature rat testis which is present both at the level of protein product and gene transcript.
(10) Due to low numbers of animals in Replica 1, the reduced Leydig cell volume was not significant after TCDD treatment; however, in Replica 2 there was a dose-dependent reduction (P < 0.01) in volume per testis of Leydig cell cytoplasm, nuclei, or total Leydig cell volume.
(11) The findings also raise the possibility that Prl may play a role in the regulation of testosterone synthesis by the prepubertal testis.
(12) Likewise, [3H]estradiol-receptor complexes from rabbit uterus, Squalus oviduct, or mouse testis bound minimally to Squalus testicular chromatin.
(13) The cells transferred were of three types, normal spleen cells, T cell-enriched spleen and lymph node cells from mice immunized with testis homogenate (TH) in complete Freund's adjuvant (CFA) and given an extract of Bordetella pertussis (BP) and the latter cells activated by in vitro culture with TH antigen for 48 h. Controls were given buffer alone.
(14) Testis weight was decreased to approximately 50% of control after eight weeks of treatment.
(15) There was a testy set of exchanges between the editor and Michael Ellis.
(16) A rare case of a seminoma developing in an atrophic testis is described and the role of testicular atrophy in tumorigenesis is discussed.
(17) The efficacy of combined cytostatic-surgical treatment was evaluated in a prospective study involving 70 patients with germinal tumors of the testis metastasizing into the lungs.
(18) Micrococcal nuclease-digested testis and erythrocyte chromatin was separated into soluble and insoluble fractions.
(19) Specific high affinity saturable binding proteins for oestradiol-17beta have been demonstrated in the cytoplasm of liver, adrenal, pituitary, prostate, epididymis and testis interstitial tissue of the rat.
(20) As for possible causes of reduced Leydig cell activity it was investigated whether the testis was (1) hypoplastic; (2) abnormally fused with the epididymis; (3) located in the abdomen; (4) or UT was associated with hypospadias.