(a.) Pertaining to, or derived from, thyme; as, thymic acid.
Example Sentences:
(1) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(2) Trisomy 15 is a frequent chromosomal abnormality found in murine thymic tumors that develop spontaneously or by induction with irradiation, chemical carcinogens, or leukemogenic retroviruses.
(3) These data suggest that there are fundamental differences in the mechanisms of induction of virally and chemically induced thymic lymphomas in AKR mice.
(4) We document for the first time abnormal microenvironments in thymomas that may offer insights into understanding normal thymic differentiation.
(5) Obvious restitution of the thymic medulla was evident about 14 days after withdrawal of FK506.
(6) Thus, MHV infection inhibits spleen T-lymphocyte activation and blocks in vitro catecholamine and cAMP regulation of spleen T-cell activation but does not affect activation of thymic cells or spleen B cells.
(7) These data suggested that an inter-thymic exchange of cells did not occur during larval life.
(8) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
(9) The recent identification among non-Hodgkin's malignant lymphomas of a high-grade malignancy entity of possible thymic origin and defined as lymphoblastic convoluted-cell lymphoma allowed the morphologic and radiological diagnosis of nine cases of this disease.
(10) Complex treatment with inclusion of thymalin resulted in an increase of the thymic factor, normalization of the lipid metabolism increase of the contractile function of the myocardium and, thus, increases the treatment efficacy.
(11) Furthermore, effector TH cells within the two compartments exert differential effector activities: splenic effector TH cells induce B cells to both proliferation and maturation, while thymic effector TH cells are defective in activating B-cell maturation.
(12) A murine model system was developed to determine whether ionizing radiation has a detrimental influence on thymic epithelium, cell function.
(13) Unlike previous studies with 13-cis-retinoic acid during the pre- and early organogenic stages of development (Hummler et al., Teratology 42:263-272, 1990), no thymic hypo- or aplasia or heart anomalies were observed, which may be attributable to the slightly longer 13-cis retinoic acid treatment period, i.e., GD 10-27.
(14) X-ray CT and MRI of the mediastinum showed images compatible with residual thymic tissue in 8 of 9 patients.
(15) Bilateral temporal epilepsies involving the limbic system on the one hand, bilateral frontal epilepsies on the other one, and P.M. status which may be paralleled, make these patients more susceptible to acute mental confusions, to acute thymic disorders, to delirious attacks.
(16) Thymulin activity was not altered throughout the study, suggesting that this thymic hormone cannot be used as a functional marker of short-term energy restriction.
(17) Four samples of thymoma obtained from patients affected by myasthenia gravis have been immunohistologically analysed on cryostat sections using a panel of antisera and monoclonal antibodies specific for antigens which define different stages of intrathymic lymphocyte differentiation and antigens specific for different types of thymic epithelial cells (cortical, medullary).
(18) In cultures of normal human thymic epithelium, we observed that the P19 protein was less expressed than in situ.
(19) In this study, thymic rosettes (TR), which are cell-cell complexes of thymic lymphocytes and stromal cells, were isolated from human thymic tissue, and were characterized.
(20) We do not yet know whether sex steroids modulate secretion of other thymic peptides.
Thymus
Definition:
(a.) Of, pertaining to, or designating, the thymus gland.
(n.) The thymus gland.
Example Sentences:
(1) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(2) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(3) In 14 of the patients the imaging results were checked against the histological findings of a subsequent thymectomy, which revealed four thymomas and (with the exception of one normal thymus) hyperplastic changes in all the others.
(4) The bursa of Fabricius, thymus glands and spleen of chickens were also shown to express mRNA coding for ANP.
(5) The resulting cortexolone-Sepharose absorbed easily the cytosolic chick thymus glucocorticoid receptor.
(6) Thymus and spleen cells from such hypogammaglobulinaemic chickens were extracted with non-ionic detergents, acid urea, or combinations of urea and detergent, and the extracts were analysed for Ig by the inhibition assay.
(7) We previously found that transfected TNP-specific B cells undergo both Ca2+ signaling and desensitization upon interaction with the thymus-dependent Ag TNP-OVA.
(8) Tryptase also efficiently hydrolyzed histone H1 from rat thymus.
(9) However, the reactions of the thymus and spleen were different in this experiment, and further studies are necessary to evaluate the mechanism of these immune reactions.
(10) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
(11) Identification of terminal deoxynucleotidyl transferase (TdT) positive cells in sites other than bone marrow, thymus, lymph nodes and peripheral blood is indicative of a TdT positive lymphoproliferative disease.
(12) Proliferative and cytollytical activity of lymphocytes was compared in lymphocyte alloimmunization of the spleen and intact thymus.
(13) We present a case of carcinoid heart disease and cardiac metastases discovered during a myocardial infarction in a 64 years-old woman who was treated for carcinod of the thymus.
(14) Skin grafts from Xenopus isogeneic to the donors of the MHC-incompatible larval and adult thymus implants are always tolerated by Tx hosts.
(15) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
(16) The heterotransplantation of minced human fetal pituitaries into adult thymus-aplastic nude mice is described.
(17) The tryptic cores from H-2K and H-2D are regularly distinguishable from the thymus-leukemia antigens (TLA) by gel electrophoresis in one dimension.
(18) Each fraction was injected with either normal bone marrow cells or normal thymus cells with antigen into 650-R-irradiated hosts.
(19) mg and showed an incidence of 57% metastases to regional popliteal nodes and 5% metastases to thymus.
(20) Mouse thymus cells, educated to poly(tyrosyl,glutamyl)-polyDLalanyl--polylysyl [(T,G)-A--L], release an antigen-specific factor on brief culture in vitro.