(superl.) Firmly held together; compact; not loose or open; as, tight cloth; a tight knot.
(superl.) Close, so as not to admit the passage of a liquid or other fluid; not leaky; as, a tight ship; a tight cask; a tight room; -- often used in this sense as the second member of a compound; as, water-tight; air-tight.
(superl.) Fitting close, or too close, to the body; as, a tight coat or other garment.
(superl.) Not ragged; whole; neat; tidy.
(superl.) Close; parsimonious; saving; as, a man tight in his dealings.
(superl.) Not slack or loose; firmly stretched; taut; -- applied to a rope, chain, or the like, extended or stretched out.
(superl.) Handy; adroit; brisk.
(superl.) Somewhat intoxicated; tipsy.
(superl.) Pressing; stringent; not easy; firmly held; dear; -- said of money or the money market. Cf. Easy, 7.
(v. t.) To tighten.
Example Sentences:
(1) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(2) The expression of the Pgp isoforms appears to be tightly regulated and, at least in some cells, under complex hormonal control.
(3) Whereas the tight junctions of endoneurial capillaries are known to prevent certain blood-borne substances from entering the endoneurium, it was not clear whether the permeability of the pulpal capillaries, which are distant from the nerve fibres, could affect the nerve fibre environment.
(4) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(5) These data indicate that topoisomerase I and RNA polymerase I are tightly complexed both in vivo and in vitro, and suggest a role for DNA topoisomerase I in the transcription of ribosomal genes.
(6) Immunofluorescence and immunoelectronmicroscopy experiments demonstrated that while tight junctions demarcate PAS-O distribution in confluent cultures, apical polarity could be established at low culture densities when cells could not form tight junctions with neighboring cells.
(7) Investigations have been made to determine the identity and binding characteristics of the pterins that are bound tightly to dihydrofolate reductases which are isolated from vertebrate sources by a well established procedure.
(8) At all times, a tight inverse correlation exists between ATP and IMP concentrations.
(9) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).
(10) This study investigates the use of the incentive inspirometer to observe the effects of tight versus loose clothing on inhalation volume with 17 volunteer subjects.
(11) In contrast, interchange of the histones and tightly bound non-histone protein DNA complexes from hormone-withdrawn and estrogen-stimulated chromatins during reconstitution did not affect the level of mRNAOV sequences produced.
(12) Using microelectrodes and various microscopic techniques active Na+ absorption as well as K+ secretion has been localized to the principal cells, while Cl- absorption was found to proceed largely, though not exclusively, through the tight junctions between cells.
(13) The successful establishment of a postcrisis SV-40 T antigen transformed epithelial cell line, 1HAEo-, which retains tight junctions and vectorial ion transport, is described.
(14) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(15) In contrast, after incubation with 0.5% DOC, the core microfilaments are no longer tightly bundled yet the lateral arms remain attached with a distinct 33-nm periodicity.
(16) The data collected by several approaches reveal that assembly and maturation of vaccinia involves a tightly coupled sequence of interrelated events including the assembly of the envelope, post-translational cleavage of several virion polypeptides, and induction of the core enzymes.
(17) The tight coupling between neuronal activity and oxidative energy metabolism forms the basis for the use of cytochrome oxidase as an endogenous metabolic marker for neurons.
(18) When using a nylon thread for the attachment of a pseudophakos to the iris, it may happen that the suture is slung tightly around the implant-lens.
(19) Some antibodies and other proteins bind tightly to nitrocellulose and dissociation of these proteins by Tween 20 is barely detectable.
(20) Independent experts warn that rumours and deliberate misinformation about the regime are rife, partly because it is impossible to verify or disprove most stories about the tightly controlled country's elite.
Tithe
Definition:
(n.) A tenth; the tenth part of anything; specifically, the tenthpart of the increase arising from the profits of land and stock, allotted to the clergy for their support, as in England, or devoted to religious or charitable uses. Almost all the tithes of England and Wales are commuted by law into rent charges.
(n.) Hence, a small part or proportion.
(a.) Tenth.
(v. t.) To levy a tenth part on; to tax to the amount of a tenth; to pay tithes on.
(v. i.) Tp pay tithes.
Example Sentences:
(1) Retired neurosurgeon Ben Carson , who is currently positioned second in the polls behind Trump, was given respectful time to explain the medical consensus dismissing what many see as crackpot theories about vaccines and autism – but was only pressed briefly on his own arguably equally crackpot assertion that any form of progressive taxation amounts to socialism and the US should opt for a biblical tithe system instead.
(2) All five cell lines had small deposits of intramembraneous alkaline phosphatase in the plasma membrane and deposits associated tith the mitochondrial membranes and the endoplasmic reticulum that were not completely inhibited by phenylalanine or Levamisole.
(3) He dined with developers in private, at a huge property junket in Cannes called Mipim, and publicly announced his grand bargain with capital: they should be allowed to build as big as they wanted, as long as he could take a tithe of the proceeds to spend on such things as affordable housing.
(4) By the end of 2003, Christ Fellowship was the church where we regularly attended services,” he recalls in American Son, “and the church we tithed to as well.
(5) A request to his campaign to clarify whether he still tithes to the church was not returned at time of publication.
(6) But this is hardly what we think of as "social enterprise" – it looks more like a kind of feudalism, run on tithes and tributes and grudging sense of noblesse oblige .
(7) What's demolished: Harmondsworth Moor, Harmondsworth, and Longford - 950 homes, and the Tithe Barn and St Mary's Church in Harmondsworth, both sites of significant heritage value.
(8) This alone is an impressive list of publications and public awards, but is a mere tithe of Carpenter's extraordinary output, which also includes magnificently researched histories of the BBC Third programme, the postwar English satire movement, American writers in Paris between the wars, the Brideshead generation, and the 'angry young men', as well as an Oxford Companion to Children's Literature.
(9) But the Conservatives clearly don’t value all inheritances, for all their noise about the evils of inheritance tax, a tithe on extreme wealth that in practice afflicts barely anyone.
(10) He tithed, donating part of his salary to his local Pentecostal church, and fasted once a week.
(11) This is what coffee can be – what coffee is – that makes artisanal devotees travel, tithe and tip for what we could never, ever get at Starbucks .
(12) I'd like to see a movement of older people helping younger people and that might take all sorts of forms, like tithing part of your winter fuel allowance if you can afford to, or mentoring.
(13) Members are expected both to sell copies of the Nation’s paper, The Final Call, and submit tithes.
(14) On Wednesday airport authorities unveiled three proposals for a third runway, one of which would mean that St Mary's and a huge tithe barn next door would almost certainly be demolished along with hundreds of homes in Harmondsworth.
(15) Near Llantwit Major, the St Donat's Arts Centre ( stdonats.com ) – in an old tithe barn within St Donats Castle, formerly a home of William Randolph Hearst – puts on regular concerts, plays and exhibitions.
(16) Malcolm Muggeridge, in his book The Thirties, described the growth of the BBC in that decade (it had 4,233 employees by July 1939) thus: “The BBC came to pass silently, invisibly; like a coral reef, cells busily multiplying, until it was a vast structure … a society, with its king and lords and commoners, its laws and dossiers and revenue and easily suppressed insurrection …” Others think of it as like a religion: its foundations are faith and trust, and it will wither away when the congregations cease to believe in it (and pay their tithes to it).