(superl.) Firmly held together; compact; not loose or open; as, tight cloth; a tight knot.
(superl.) Close, so as not to admit the passage of a liquid or other fluid; not leaky; as, a tight ship; a tight cask; a tight room; -- often used in this sense as the second member of a compound; as, water-tight; air-tight.
(superl.) Fitting close, or too close, to the body; as, a tight coat or other garment.
(superl.) Not ragged; whole; neat; tidy.
(superl.) Close; parsimonious; saving; as, a man tight in his dealings.
(superl.) Not slack or loose; firmly stretched; taut; -- applied to a rope, chain, or the like, extended or stretched out.
(superl.) Handy; adroit; brisk.
(superl.) Somewhat intoxicated; tipsy.
(superl.) Pressing; stringent; not easy; firmly held; dear; -- said of money or the money market. Cf. Easy, 7.
(v. t.) To tighten.
Example Sentences:
(1) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(2) The expression of the Pgp isoforms appears to be tightly regulated and, at least in some cells, under complex hormonal control.
(3) Whereas the tight junctions of endoneurial capillaries are known to prevent certain blood-borne substances from entering the endoneurium, it was not clear whether the permeability of the pulpal capillaries, which are distant from the nerve fibres, could affect the nerve fibre environment.
(4) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(5) These data indicate that topoisomerase I and RNA polymerase I are tightly complexed both in vivo and in vitro, and suggest a role for DNA topoisomerase I in the transcription of ribosomal genes.
(6) Immunofluorescence and immunoelectronmicroscopy experiments demonstrated that while tight junctions demarcate PAS-O distribution in confluent cultures, apical polarity could be established at low culture densities when cells could not form tight junctions with neighboring cells.
(7) Investigations have been made to determine the identity and binding characteristics of the pterins that are bound tightly to dihydrofolate reductases which are isolated from vertebrate sources by a well established procedure.
(8) At all times, a tight inverse correlation exists between ATP and IMP concentrations.
(9) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).
(10) This study investigates the use of the incentive inspirometer to observe the effects of tight versus loose clothing on inhalation volume with 17 volunteer subjects.
(11) In contrast, interchange of the histones and tightly bound non-histone protein DNA complexes from hormone-withdrawn and estrogen-stimulated chromatins during reconstitution did not affect the level of mRNAOV sequences produced.
(12) Using microelectrodes and various microscopic techniques active Na+ absorption as well as K+ secretion has been localized to the principal cells, while Cl- absorption was found to proceed largely, though not exclusively, through the tight junctions between cells.
(13) The successful establishment of a postcrisis SV-40 T antigen transformed epithelial cell line, 1HAEo-, which retains tight junctions and vectorial ion transport, is described.
(14) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(15) In contrast, after incubation with 0.5% DOC, the core microfilaments are no longer tightly bundled yet the lateral arms remain attached with a distinct 33-nm periodicity.
(16) The data collected by several approaches reveal that assembly and maturation of vaccinia involves a tightly coupled sequence of interrelated events including the assembly of the envelope, post-translational cleavage of several virion polypeptides, and induction of the core enzymes.
(17) The tight coupling between neuronal activity and oxidative energy metabolism forms the basis for the use of cytochrome oxidase as an endogenous metabolic marker for neurons.
(18) When using a nylon thread for the attachment of a pseudophakos to the iris, it may happen that the suture is slung tightly around the implant-lens.
(19) Some antibodies and other proteins bind tightly to nitrocellulose and dissociation of these proteins by Tween 20 is barely detectable.
(20) Independent experts warn that rumours and deliberate misinformation about the regime are rife, partly because it is impossible to verify or disprove most stories about the tightly controlled country's elite.
Wet
Definition:
(superl.) Containing, or consisting of, water or other liquid; moist; soaked with a liquid; having water or other liquid upon the surface; as, wet land; a wet cloth; a wet table.
(superl.) Very damp; rainy; as, wet weather; a wet season.
(superl.) Employing, or done by means of, water or some other liquid; as, the wet extraction of copper, in distinction from dry extraction in which dry heat or fusion is employed.
(superl.) Refreshed with liquor; drunk.
(a.) Water or wetness; moisture or humidity in considerable degree.
(a.) Rainy weather; foggy or misty weather.
(a.) A dram; a drink.
(imp. & p. p.) of Wet
(v. t.) To fill or moisten with water or other liquid; to sprinkle; to cause to have water or other fluid adherent to the surface; to dip or soak in a liquid; as, to wet a sponge; to wet the hands; to wet cloth.
Example Sentences:
(1) During periods of wet steam it was impossible to maintain consistent sterility of the mouse pellets even using a cycle of 126 degrees C for 60 minutes.
(2) Azure B also reduced the wet weight of carrageenin-induced granulomas in rats.
(3) The various changes were accompanied by a marked reduction in the overall wet weight of the vertebrae.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) Just when Everton thought they might start 2014 by keeping Liverpool out of the Champions League positions, they came close to failing the wet Wednesday at Stoke test thanks to a goal from an Anfield loanee.
(6) This led to an increase in liver wet weight and total DNA.
(7) The parameters of LES relaxation for both wet and dry swallows were similar using either a carefully placed single recording orifice or a Dent sleeve.
(8) During DOCA treatment over 4 weeks, the decrease of muscle wet weight was greater in the EDL muscles.
(9) Lipase level per unit wet tissue and total pancreatic levels increased from 2 to 35 d of age in suckling pigs (P less than .01).
(10) Collagen concentrations based on wet or dry weight and glycosaminoglycan concentrations based on wet weight decreased during this period.
(11) A new wet-state membrane characterization method, thermoporometry, was used to study the effect on membrane structure of commonly used sterilization methods for artificial kidney membranes.
(12) All but one of the isolations were made from moist or wet samples.
(13) Systemic administration of drugs that augment 5-HT2 activity generally induces 'wet dog' shaking (WDS) in rats.
(14) Sixteen patients who remained wet had detrusor instability; 9 of these were cured by anticholinergic medications.
(15) In the HCD group, 66 (86.8%) pressure sores improved compared with 36 (69.2%) pressure sores in the wet-to-dry dressings group.
(16) The after-discharge induced by subconvulsant electrical stimulations, is followed by a behavioral phenomenon, named Wet Dog Shakes (WDS).
(17) The deleted peptide corresponds precisely to the sequence coded by exon 46 of the normal pro-alpha 1(I) gene (Chu, M.-L., de Wet, W., Bernard, M., Ding, J.F., Morabito, M., Myers, J., Williams, C., and Ramirez, F. (1984) Nature 310, 337-340).
(18) Associated with this increase in epidermal wet weight is a two times increase in the number of epidermal cells per millimeter of interfollicular epidermis.
(19) The umpires allow them a different one, perhaps because the previous incumbent was wet - it landed in a puddle, where the water-sucking thing had egested, apparently.
(20) Supporting a Sunderland side who had last won a home Premier League game back in January, when Stoke City were narrowly defeated, is not a pursuit for the faint-hearted but this was turning into the equivalent of the sudden dawning of a gloriously hot sunny day amid a miserable, cold, wet summer.