(n.) A hydrocarbon, C6H5.CH3, of the aromatic series, homologous with benzene, and obtained as a light mobile colorless liquid, by distilling tolu balsam, coal tar, etc.; -- called also methyl benzene, phenyl methane, etc.
Example Sentences:
(1) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
(2) The toluene group were more approving in their attitudes towards taking other drugs.
(3) In anaerobiosis, at 25 mM sulphanilic acid, or with addition of p-toluene sulphonic acid only one regression line is obtained for the permeation in both directions.
(4) Their defect in DNA degradation was shown not only after treatment by toluene but also in crude extracts after cell disintegration by ultrasonic and in untreated starved cultures.
(5) The significance of the present findings on the mutual suppression of metabolism between benzene and toluene is discussed in relation to solvent toxicology and biological monitoring of exposure to the solvents.
(6) On the other hand, with simultaneous doses of the two substances, the blood toluene concentration was higher for the first 15-30 min than the ethanol control and the urinary excretion of hippuric acid, a main metabolite of toluene, was markedly decreased for the first 2 h. The blood ethanol in this group, on the contrary, was reduced until 1 h after administration.
(7) Toluene exposure for 4 and 12 weeks caused a significant, approximately 20%, increase in 45Ca2+ uptake into unstimulated synaptosomes.
(8) Furthermore, toluene undergoes methyl-substitution in preparations of human bone marrow incubated with S-adenosyl-L-methionine to yield o-xylene, m-xylene, and p-xylene.
(9) We have investigated the whole-body dermal penetration of styrene, xylene, toluene, perchloroethylene, benzene, halothane, hexane, and isoflurane in rats and compared the permeability constants with available human studies on vapor penetration.
(10) The metabolites were identified as a) 3-hydroxy-2,6-DAT, b) 4-hydroxy-2-acetylamino-6-aminotoluene, c) 2-acetylamino-6-aminotoluene, and d) 2,6-di(acetylamino)-toluene.
(11) Thus chronic toluene inhalation even at small concentrations changes hypothalamic reactivity in response to stress and hormonal stimuli.
(12) The coefficient to the complex action of carbon oxide and heating microclimate is equal to 2.5 and toluene++ and heating microclimate to 1.9.
(13) Expired carbon dioxide (CO2), the most sensitive index, displayed an inverted U-shaped concentration-effect curve, which increased at 100 ppm (the TLV) and decreased at 4500 ppm toluene.
(14) The paint base consisted primarily of toluene and methyl ethyl ketone.
(15) As organic solvents, 1,1,1-trichloroethane (1,1,1-TCE), trichloroethylene, tetrachloroethylene, toluene, m-xylene and trichloro-trifluoroethane (FC-113) were used in this study.
(16) There was a negative association between blood toluene and plasma levels of prolactin.
(17) Ethanol-withdrawn animals displayed an increased sensitivity to the narcotic action of toluene.
(18) One possibility is that early synaptic alterations resulting from toluene exposure may be preceded by increases in outer membrane fluidity.
(19) In experiments in vitro, neither benzene, toluene nor xylene changed the number of sister-chromatid exchanges (SCEs) or the number of chromosomal aberrations in human lymphocytes.
(20) Benzene toluene, styrene, 1,1,1-trichloroethylene, and tetrachloroethylene are taken as examples of solvents showing various toxicokinetic properties.
Toluol
Definition:
(n.) Alt. of Toluole
Example Sentences:
(1) After 4 months of toluol inhalation, the levels of estradiol and progesterone decrease in the blood.
(2) The authors explored the tissue and intracellular distribution in the body of xenobiotics (aniline-1-14C hydroclorate, dioxane-1,4-14C, toluol-1-14C, phenol-1-14C and 1,2-14C ethylene glycol) following their administration in single doses to white rats.
(3) After an acute and subacute toluol intoxication decrease of the PAS-positive and Bestcarmin positive material in the liver and increase of the activity of SDH were observed.
(4) The degree of the damage to the hepatic tissue depends on the doses of toluol and on the duration of the administration.
(5) The hepatotoxic effect of the analytically pure toluol and a toluol being used in the Chemical Factory "Tiszai" was investigated.
(6) The hepatotoxic effect of the analitically pure toluol and a toluol neing used in the Chemical Factory "Tiszai" was investigated.
(7) As an effect of small doses of toluol degenerative changes-enlargement of the cysternae of the endoplasmatic reticulum, separation of ribosomes, increase of the number of autophag-vacuola-could be seen.
(8) These events do not happen after toluol inhalation.
(9) Single toxic and various subtoxic doses of toluol were administered intraperitoneally and subeutaneously to male rats of CFY.
(10) The histochemical procedures are carried out at sections of 7-8 microns after removal of plastic with xylene and toluol.
(11) The workers of metal industry were exposed to the following respiratory noxa: toluol, paint aerosol, mineral dusts (SiO2 up to 10%), asbestos dust, metalic dust and several chemical noxa (acetone, CO, CO2, ZnO, FeO and petrol).
(12) The culture treatment with toluol increased the amounts of the determinable induced enzyme 4-26 times, 30 to 80 percent of the induced enzyme were liberated from the cells into the supernatant.
(13) The ethrane was subsequently desorbed in toluol and quantified by gas chromatography.
(14) In particular an organic solvent, especially trichlorethylene as well as toluol was taken into consideration, the poisoning through trichlorethylene being proved conclusively.
(15) The Vibratome-cut slices are dehydrated through a graded series of acetone, cleared in toluol and flat-embedded in Paraplast Plus embedding medium.
(16) PAA is extracted with toluol and nitrated with potassium nitrate solution in concentrated sulphuric acid followed by reduction of nitrophenylacetic acid into aminophenylacetic acid with zinc powder.
(17) Best results were obtained by means of Silica gel plates, the toluol-aceton solvent (85:15), and the developer of a diazosalt 0.4% in an alcohol 20% sodiumhydroxide.
(18) The obtained findings have shown that dominating inter-impulse intervals in the area of 1000 and more ms, and multimodality of their distribution occur in benzene, toluol, xylol injection within time-structure of some neurons activity of sensomotor cortex, hippocampus, thalamus and lateral hypothalamus.
(19) Single toxic- and various subtoxic doses of toluol were administered to male rats of CFY intraperitoneally and subcutaneously.
(20) Three sorbents were employed to establish the most appropriate conditions for the application of a fast, readily applicably and highly sensitive method--silica gel G, DG and Kiselgur "Merk", as well as 14 mobile phases--monocompound (n-hexane, n-heptane, acetone benzol and toluol), double combinations (hexane-acetone 4:1, hexane-acetone 9:1, hexane-benzol 1:1, hexane-benzol 4:1, heptane-acetone 7:1, benzol-hexane 4:1, benzol-acetone 9:1, and petrolium ether-tetrachlormethane) and triple combinations (acetone-toluol-hexane 1:15 and 5 developers (a diazosalt, bromine vapours + diazosalt, palladium bichloride, bromphenol blue, and silver nitrate, sodium hydroxide, ammonia gas).