(n.) Sound, or the character of a sound, or a sound considered as of this or that character; as, a low, high, loud, grave, acute, sweet, or harsh tone.
(n.) Accent, or inflection or modulation of the voice, as adapted to express emotion or passion.
(n.) A whining style of speaking; a kind of mournful or artificial strain of voice; an affected speaking with a measured rhythm ahd a regular rise and fall of the voice; as, children often read with a tone.
(n.) A sound considered as to pitch; as, the seven tones of the octave; she has good high tones.
(n.) The larger kind of interval between contiguous sounds in the diatonic scale, the smaller being called a semitone as, a whole tone too flat; raise it a tone.
(n.) The peculiar quality of sound in any voice or instrument; as, a rich tone, a reedy tone.
(n.) A mode or tune or plain chant; as, the Gregorian tones.
(n.) That state of a body, or of any of its organs or parts, in which the animal functions are healthy and performed with due vigor.
(n.) Tonicity; as, arterial tone.
(n.) State of mind; temper; mood.
(n.) Tenor; character; spirit; drift; as, the tone of his remarks was commendatory.
(n.) General or prevailing character or style, as of morals, manners, or sentiment, in reference to a scale of high and low; as, a low tone of morals; a tone of elevated sentiment; a courtly tone of manners.
(n.) The general effect of a picture produced by the combination of light and shade, together with color in the case of a painting; -- commonly used in a favorable sense; as, this picture has tone.
(v. t.) To utter with an affected tone.
(v. t.) To give tone, or a particular tone, to; to tune. See Tune, v. t.
(v. t.) To bring, as a print, to a certain required shade of color, as by chemical treatment.
Example Sentences:
(1) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(2) In summary, GABAergic tone did not effect basal acid secretion in anesthetized rats.
(3) After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05).
(4) All of this in the same tones of weary nonchalance you might use to stop the dog nosing around in the bin.
(5) More disturbing than his ideas was Malema's style and tone.
(6) Noradrenaline decreased the phasic contraction amplitude of the circular muscle and exerted a stimulant effect on the tone which suggested an existence of two alpha 1-adrenoceptor subtypes.
(7) Histamine (10(-6)-10(-4) M) induced concentration-dependent increases in tone and Ca2+i, but these responses were not sustained.
(8) Masking experiments are demonstrated for electrical frequency-modulated tone bursts from 1,000 to 10,000 cps and from 10,000 to 1,000 cps with superimposed clicks.
(9) The stimuli were two simple tones in experiment 1 and two tonal complexes in both experiments 2 and 3.
(10) Isolated outer hair cells from the organ of Corti of the guinea pig have been shown to change length in response to a mechanical stimulus in the form of a tone burst at a fixed frequency of 200 Hz (Canlon et al., 1988).
(11) Complex tones containing the first 20 harmonics of 50, 100, or 200 Hz, all at equal amplitude, were used.
(12) An attempt to eliminate the age effect by adjusting for age differences in monaural shadowing errors, fluid intelligence, and pure-tone hearing loss did not succeed.
(13) Inhibition of the production or action of these substances will allow for vasodilatation, and it is probable that perinatal pulmonary vascular tone reflects a balance between local prostaglandin and leukotriene production.
(14) Subject evaluations in accordance with the intensity levels of tones, i.e.
(15) Maximum expiratory flow on partial flow-volume curve at 25% forced vital capacity (PEF25) was measured as an index showing basal bronchomotor tone.
(16) Twenty-four hours later, a stimulus generalization test was conducted in the absence of drug; during this session, tones that varied in frequency around 4.5 KHz were presented while the animals were responding under the VI schedule.
(17) Auditory sensory perception was operationalized as number of tones heard on audiometric examination.
(18) Later, Lucas, also a former party leader, strongly defended Bennett, saying it was a “bad day for Natalie” but there was also “kind of a gloating tone that strikes one as having something to do with her being a woman in there too”.
(19) From a set of tones that varied only in intensity, it was possible to calculate the growth of loudness with intensity for the budgerigar.
(20) Two hundred forty-six fetuses had at least one abnormal biophysical profile variable with the risk of bad outcome, for a single abnormal variable, ranging from 8% (body movements) to 100% (tone) and increasing from 14% (any variable abnormal) to 63% (all variables abnormal).
Tonic
Definition:
(a.) Of or relating to tones or sounds; specifically (Phon.), applied to, or distingshing, a speech sound made with tone unmixed and undimmed by obstruction, such sounds, namely, the vowels and diphthongs, being so called by Dr. James Rush (1833) " from their forming the purest and most plastic material of intonation."
(a.) Of or pertaining to tension; increasing tension; hence, increasing strength; as, tonic power.
(a.) Increasing strength, or the tone of the animal system; obviating the effects of debility, and restoring healthy functions.
(n.) A tonic element or letter; a vowel or a diphthong.
(n.) The key tone, or first tone of any scale.
(n.) A medicine that increases the strength, and gives vigor of action to the system.
Example Sentences:
(1) It is suggested that diabetes causes selective changes in the functioning of Gi in adipocyte membranes which removes the tonic GTP-dependent inhibitory function of this G-protein.
(2) Other Christmas favourites, including stollen, organic mince pies and Schweppes tonic will also be included among 100 seasonal products on the list of 1,000 items which shoppers can choose from over the next few months.
(3) In intact cell preparations, diamide produced a slow tonic contraction, consistent with myofibril activation.
(4) However, tetanic stimulation gave the same results as in untreated preparations when the tonicity was increased.
(5) Stimulus-response characteristics suggested that this system was well suited for a role in tonic inhibition of sympathetic activity.
(6) The amplitude was 15-70% as large as the tonic component of the K-contracture induced by 40 mM K. Theophylline (10 mM), 0.1 mM papaverine and 1 microM isoprenaline nearly abolished, and 1 mM cAMP partly depressed the tonic contraction of K-contracture, whereas the tonic contraction induced by the test solution was unaffected.
(7) While tonic pupil and reduced sweating can be attributed to the affection of postganglionic cholinergic parasympathetic and sympathetic fibres projecting to the iris and sweat glands, respectively, the pathogenesis of diminished or lost tendon jerks remains obscure.
(8) Some organization schemes concerning locomotor and scratching rhythmicity generators are considered, such as: two half-centres with reciprocal inhibitory connections and tonic excitatory influences on these half-centres: two half-centres with inhibitory-excitatory connections and tonic excitatory influences on one half-centre; ring structures consisting of more than two functional groups of neurons with excitatory and inhibitory connections between them.
(9) Overall, carbamazepine and phenytoin are recommended drugs of first choice for single-drug therapy of adults with partial or generalized tonic-clonic seizures or with both.
(10) It was previously believed that the period of the circadian clock was primarily responsive to externally imposed tonic or phasic events.
(11) For now, he leans on the bar – a big man, XL T-shirt – and, in a soft Irish accent, orders himself a small gin and tonic and a bottle of mineral water.
(12) Relying on traditional medicine, all 20 women reported eating brown seaweed soup for 20 days after childbirth, and 5 said that they took tonic herbs during the puerperium.
(13) Amplitudes of the tonic response evoked by 39 mM-K+ in intact muscle tissues and the contraction induced by 0.3 microM-Ca2+ in skinned muscle were much the same.
(14) Tonic sympathetic neural control of heart rate was inferred from bradycardia after treatment with the adrenergic neuron-blocking agent, bretylium tosylate.
(15) These results clearly indicate that in both intact and OVX does, endogenous NPY is in part responsible for maintaining basal, tonic LH secretion.
(16) All motoneuron firing during fictive swimming is associated with a tonic depolarization that falls away slowly once firing stops, is increased by hyperpolarizing current, and is reduced by depolarizing current.
(17) The tonic influences were expressed in an increase in the amplitude parameters of the responses of the visual cortex in conditions of the formation in the posterolateral nucleus of the thalamus of a focus of heightened excitability (anode polarization), and their perceptible diminution with potassium depression in this nucleus.
(18) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(19) During each session, measurements were made of either tonic accommodation or tonic vergence 30 s before stimulus onset and at 0.5, 2, 4, 6, 8, 10, 12, and 14 min after stimulus offset.
(20) The findings can be summarized as follows: (1) The effective concentration of SDS for termination of shark tonic immobility (an immediate and fast response) was close to its critical micellar concentration in sea water (70 microM).