What's the difference between topical and toxical?
Topical
Definition:
(n.) Of or pertaining to a place; limited; logical application; as, a topical remedy; a topical claim or privilege.
(n.) Pertaining to, or consisting of, a topic or topics; according to topics.
(n.) Resembling a topic, or general maxim; hence, not demonstrative, but merely probable, as an argument.
Example Sentences:
(1) Furthermore, all of the sera from seven other patients with shock reactions following the topical application of chlorhexidine preparation also showed high RAST counts.
(2) Topical and systemic antibiotic therapy is common in dermatology, yet it is hard to find a rationale for a particular route in some diseases.
(3) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(4) The discussion on topics like post-schooling and rehabilitation of motorists has intensified the contacts between advocates of traffic law and traffic psychologists in the last years.
(5) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.
(6) Health information dissemination is severely complicated by the widespread stigma associated with digestive topics, manifested in the American public's general discomfort in communicating with others about digestive health.
(7) Female CD-1 mice were initiated with 200 nmol 7,12-dimethylbenz[a] anthracene and topically promoted three times weekly for 20 weeks with doses of 25, 50, 100, or 200 nmol mirex.
(8) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(9) "This will obviously be a sensitive topic for the US administration, but partners in the transatlantic alliance must be clear on common rules of engagement in times of conflict if we are to retain any moral standing in the world," Verhofstadt said.
(10) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(11) The tetracaine component of TAC is superfluous for obtaining topical anesthesia of minor dermal lacerations of the face in children.
(12) I think we are still trying to understand all that and I think that fits under the broader topic of social licence and what bringing in automation to an area does to that region as a whole, which we don’t quite know yet.” Could carbon farming be the answer for a 'clapped-out' Australia?
(13) UPDATE II [Tues.] Two other items that may be of interest: first, Guardian editor-in-chief Alan Rusbridger was the guest for the full hour yesterday on Democracy Now, discussing the paper's role in reporting the NSA stories, and the video and transcript of the interview are here ; second, marking our collaboration on a series of articles about spying on Indians, the Hindu has a long interview with me on a variety of related topics, here .
(14) CNS excitation and seizures, manifestations of organochlorine intoxication, can occur following ingestion or inappropriate application of the 1 per cent topical formulation of lindane used to treat scabies and lice.
(15) A water based 5% benzoyl peroxide gel (Benzac W5) was compared with topical 1% clindamycin phosphate solution (Cleocin T) in the treatment of acne vulgaris using a randomized, investigator blind study design.
(16) In conclusion, this study indicates that topical CsA is capable of locally suppressing a strong T-cell-mediated immune response after an initial short-term systemic dose of CsA.
(17) Poly(ortho ester) bioerodible polymers are suitable materials for the topical administration of a wide variety of therapeutic agents; varying the nature and amounts of excipients physically incorporated into the polymer will vary the erosion rates from a few hours to many months.
(18) Future studies will need to carefully evaluate the vehicle used and the strength of topical CsA employed.
(19) The animal model of psoriasis was effectively treated by bimolane, both systemically and topically, and also by parenteral methotrexate and topical betamethasone valerate.
(20) Data were compared with those from a previous study with topical 1% minoxidil solution.
Toxical
Definition:
(a.) Of or pertaining to poison; poisonous; as, toxic medicines.
Example Sentences:
(1) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(4) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(5) The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.
(6) Results suggest that Cd-MT is reabsorbed and broken down by kidney tubule cells in a physiological manner with possible subsequent release of the toxic cadmium ion.
(7) Previous studies have not evaluated the potential for oxygen toxicity at 9.5 psia.
(8) They more precisely delineate the hazard identification process and the factors important in supporting risk decisions for developmental toxicants than does any other document.
(9) Accidentally discovered nearly 40 years ago as the first true antidepressants, the MAOIs soon fell into disfavor due to concerns about toxicity and seemingly lesser efficacy compared with the newer tricyclic compounds.
(10) The results confirm studies performed in our laboratory on cytotoxicity and on functional membrane proteins of fungal and mammalian cells [1,2], suggesting a common mechanism of toxicity by the action of hydrophobic xenobiotics on biomembranes.
(11) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(12) None of the compounds proved active against the replication of retroviruses (human immunodeficiency virus, murine sarcoma virus) at concentrations that were not toxic to the host cells.
(13) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(14) Diminished CMD was most common with AR (7 of 12) but was also seen with acute tubular necrosis (2 of 6) and cyclosporin toxicity (2 of 3).
(15) Histopathological studies confirmed that mice fed 933cu-rev died from bilateral renal cortical tubular necrosis consistent with toxic insult, perhaps due to Shiga-like toxins.
(16) Research must continue to determine the optimal regimen that suppresses testosterone activity with the least amount of toxicity.
(17) In South Africa, health risks associated with exposure to toxic waste sites need to be viewed in the context of current community health concerns, competing causes of disease and ill-health, and the relative lack of knowledge about environmental contamination and associated health effects.
(18) Analysis of 156 records relating to patients at the age of 15 to 85 years with extended purulent peritonitis of the surgical and gynecological genesis (the toxic phase, VI category ASA) showed that combination of programmed sanitation laparotomy and intensive antibacterial therapy performed as short-term courses before, during and after the operation with an account of the information on the nature of the microbial associations and antibioticograms was an efficient procedure in treatment of severe peritonitis.
(19) Treatment was monitored by simple measurements, and it's toxicity proved to be scanty.
(20) And adding to this toxic mix, was the fear that the hung parliament would lead to a weak government.