(1) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(2) Arteries treated with atrial natriuretic peptide showed no alterations in relaxation or cGMP content after incubation with pertussis toxin.
(3) The mechanism by which pertussis toxin (PT) breaks the unresponsiveness of delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) was examined in B10 mice.
(4) Cloned genes encoding pertussis toxin from B. pertussis were transferred into Bordetella bronchiseptica and Bordetella parapertussis by conjugation.
(5) Strains 1120-A-83-013 and B205BT produced considerably higher levels of dermonecrotic toxin activity than did strains CSU-P-1 and 64-C-0406.
(6) The phosphorylation pattern was affected by the addition of cholera toxin or GDP beta S to the isolated nuclei.
(7) Histopathological studies confirmed that mice fed 933cu-rev died from bilateral renal cortical tubular necrosis consistent with toxic insult, perhaps due to Shiga-like toxins.
(8) Cholera toxin-catalysed ADP-ribosylation identified two forms of Gs alpha-subunits whose labelling was about 4-fold greater in membranes from diabetic animals compared with those from lean animals.
(9) The slope of the thermal inactivation curve of enterotoxin A in beef bouillon (initial pH 6.2) was found to be approximately 27.8 C (50 F) with three different concentrations of toxin.
(10) The antibodies were used for identifying cross-reacting proteins in individual C. s. scutulatus and other Crotalus venoms and to isolate Mojave toxin.
(11) Antisera were raised against intact crotoxin (Crotalus durissus terrificus), Mojave toxin (Crotalus scutulatus scutulatus) and concolor toxin (Crotalus viridis concolor), as well as the subunits of crotoxin.
(12) Interestingly, different mechanisms of nucleated and non-nucleated TC directed lysis by CD4+ effectors were implied by distinct patterns of sensitivity to cholera toxin (CT) and cyclosporin A (CsA).
(13) The second step occurs several hours later and consists of the transactivation of adenylate cyclase and pertussis toxin genes.
(14) The toxins preferentially attenuate a slow phase of KCl-evoked glutamate release which may be associated with synaptic vesicle mobilization.
(15) Bordetella pertussis and Bacillus anthracis, two taxonomically distinct bacteria, secrete adenylate cyclase toxins that are activated by the eukaryotic protein calmodulin.
(16) Approximately a third of patients had stools that were positive for C difficile by either toxin or culture.
(17) The binding of radioidinated cholera toxin on its solidified antibody was inhibitable by unlabeled cholera toxin and cholera toxin antibody.
(18) To facilitate detoxification, the centrifuge is employed to provide plasma rich in toxins, but void of potentially interfering blood components such as platelets and whole blood cells.
(19) The toxins all create pores in the cell membrane of target cells leading to eventual cell lysis and they appear to require Ca2+ for cytotoxic activity.
(20) A state of net secretory fluid flux was induced in isolated jejunal loops in weanling pigs by adding theophylline or cholera toxin to the lumen of the isolated loops.
Vaccine
Definition:
(a.) Of or pertaining to cows; pertaining to, derived from, or caused by, vaccinia; as, vaccine virus; the vaccine disease.
(n.) The virus of vaccinia used in vaccination.
(n.) any preparation used to render an organism immune to some disease, by inducing or increasing the natural immunity mechanisms. Prior to 1995, such preparations usually contained killed organisms of the type for which immunity was desired, and sometimes used live organisms having attenuated virulence. since that date, preparations containing only specific antigenic portions of the pathogenic organism are also used, some of which are prepared by genetic engineering techniques.
Example Sentences:
(1) We were able to detect genetic recombination between vaccine strains of PRV following in vitro or in vivo coinoculation of 2 strains of PRV.
(2) Attempts are now being made to use this increased understanding to produce effective killed vaccines that produce immune responses in the lung.
(3) We have measured the antibody specificities to the two polysaccharides in sera from asymptomatic group C meningococcal carriers and vaccinated adults by a new enzyme-linked immunosorbent assay (ELISA) procedure using methylated human serum albumin for coating the group C polysaccharide onto microtiter plates.
(4) The simultaneous administration of the yellow fever vaccine did not influence the titre of agglutinins induced by the classic cholera vaccine.
(5) Before carrier vaccines are applied, these risks must be thoroughly evaluated case-by-case.
(6) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(7) The prophylactic effect of immunization with P. aeruginosa polyvalent corpuscular vaccine has been shown on the model of P. aeruginosa generalized chronic infection in mice with leukopenia induced by the intraperitoneal injection of cyclophosphamids.
(8) The data support inclusion of these residues in future CS protein vaccines.
(9) By vaccinating adult dogs in boarding kennels the morbidity rate dropped from 83.5% to 6.5% and the mortality rate from 4.1% to 0.5%.
(10) It is clear that before general release of a new living feline infectious enteritis vaccine, there must be satisfactory evidence that concurrent infection will not affect the safety of the modified antigen.In cats infected with feline infectious enteritis there appears to be a short period, coinciding with the onset of leucopaenia, during which they are highly infectious.
(11) The combination vaccine consisted of 12 Lf tetanus toxoid and 10 TCID50 vaccinia virus "MVA" preserved with gelatine and glucosamine.
(12) We evaluated the safety and efficacy of a conjugate vaccine that links the H. influenzae type b capsular polysaccharide to the outer-membrane protein complex (OMPC) of Neisseria meningitidis serogroup B.
(13) The litter size of vaccinated gilts was larger than that of the control gilts.
(14) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(15) The value of benefit-risk, benefit-cost, and cost-effectiveness analyses lies not in providing the definitive basis for a decision on vaccine use or evaluation.
(16) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(17) For the purpose of studying the role of elastase and protease of Pseudomonas aeruginosa in bacterial infection in burns, the effects of the vaccines made from each enzyme, their toxoids and OEP on protection against infection in burned mice were studied.
(18) No vaccination reactions were noted, although most birds involved in the trials were carrying Mycoplasma spp.
(19) Serum from piglets of vaccinated sows had no more bactericidal activity than did sera from non-vaccinated sows.
(20) The purpose of this study was to investigate a tumor cell vaccine delivered via peripheral lymphatics as maintenance therapy after induction of remission with chemotherapy.