(1) To explore an early step, we synthesized 5 beta-cholest-7-ene-3 beta,6 alpha,14 alpha-triol in tritiated form.
(2) In 7 cases endothelial cells isolated from the LP zones were more resistant to Triol-induced injury, in 2 cases the differences were not significant.
(3) A monoclonal antibody, designated MAb-25-6, monospecific for cytochrome P-450(25) was, after coupling to Sepharose, able to bind to cytochrome P-450(25) and to immunoprecipitate the activity for 25-hydroxylation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol and vitamin D3 as well as that for 16 alpha-hydroxylation of testosterone when assayed in a reconstituted system.
(4) Two human lymphoblast cell lines, LICR-LON-HMy2 (HMy2 cells) and GM4672A cells, are moderately growth inhibited by dexamethasone (1,4-pregnadien-9-fluoro-16 alpha-methyl-11 beta, 17 alpha, 21-triol-3,20-dione) (Dex).
(5) The polymorphic behavior of three series of tris-homoacyl (C14:0, C16:0 and C18:0) cyclopentane-1,2,3-triol analogs of the natural saturated triglycerides has been studied using differential thermal analysis, Fourier transform infrared spectroscopy, and X-ray diffraction.
(6) Dexamethasone (1,4-pregnadiene-9-fluor-16alpha-methyl-11beta,17alpha,21-triol-3,20-dione), a potent synthetic glucocorticoid, stimulates mouse mammary tumor virus expression 10- to 20-fold in tissue culture cells.
(7) The basic compound is the 35-aminobacteriohopane-32,33,34-triol, from which the other two hopanoids are derived by introduction of a tryptophanyl or an ornithinyl moiety linked to the amino group at C-35 via an amide linkage.
(8) This preparation upon reconstitution with cytochrome P-450 reductase and microsomal lipid catalyzed the formation of three triols, 5 alpha-androstane-3 beta, 7 beta, 17 beta-triol, 5 alpha-androstane-3 beta, 6 alpha, 17 beta-triol, and 5 alpha-androstane-3 beta, 7 alpha, 17 beta-triol from 3 beta-diol in the ratio 1:7:3.
(9) Three cholesterol derivatives, each bearing two hydroxyl groups, were intermediate activators between cholesterol and cholestane triol.
(10) The triol was found to be very potent in lowering the levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Chinese hamster ovary cells.
(11) d-Catechin (alpha-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol) is an important hepatotropic drug.
(12) Reduction of this mixture 1 with sodium aluminum bis-(methoxyethoxy)hydride furnished the 11 beta, 18, 21-triol 2a.
(13) (1) (2S,3R,4R,6R)-3,4-O-Carbonyl-7,7-dimethylenedithio-2,4,6-trimet hylnonane-1,3,4-triol, C15H26O4S2, M(r) = 334.49, triclinic, P1, a = 6.460 (2), b = 8.917 (3), c = 15.616 (5) A, alpha = 83.60 (3), beta = 83.41 (2), gamma = 89.52 (2) degrees, V = 888.0 (5) A3, Z = 2, Dx = 1.25 g cm-3, mu = 2.980 cm-1, lambda (Mo K alpha) = 0.7107 A, F(000) = 360, T = 298 K, R = 0.0465 for 1832 reflections [Fo greater than or equal to 4 sigma (Fo)].
(14) Presence of this new product represents the first example of testosterone conversion to 5 alpha-androstane-3 alpha,16 alpha,17 beta-triol and confirms our previous observation that 16 alpha-hydroxylation of 5 alpha-reduced androgens can occur in the rat testis.
(15) Exposure of cultured vascular endothelial cell monolayers to LDL enriched with Triol reduced EBF, measured as an increase in transendothelial albumin transfer, whereas cholesterol enrichment, like un-enriched LDL, had no effect on EBF.
(16) Minor metabolites of T-2 toxin in bile were identified as 3'-hydroxy HT-2 toxin (TC-3), 3'-hydroxy-7-hydroxy HT-2 toxin (TC-6), and the glucuronide form of T-2 triol (trace amount).
(17) A 3beta5alpha6beta-triol was not more inhibitory than a comparable 3beta,6beta-diol.
(18) In the other bacterial strains the diol was more mutagenic than the triol, the difference in potency being largest in strain TA 100 (2.5- to 10-fold, depending on the experimental conditions).
(19) The methyl ester of V (A or B) was treated with methyl magnesium iodidi in ether to provide the desired triol, VI (A and B).
(20) Radioactivities of each fraction in lipoproteins separated by thin layer chromatography showed that fractions containing cholestane-3 beta,5 alpha,6 beta-triol, 7 alpha- and 7 beta-hydroxycholesterol and 7-ketocholesterol were more selectively transported in VLDL, whereas most of the 25-hydroxycholesterol was present in LDL.
Triple
Definition:
(a.) Consisting of three united; multiplied by three; threefold; as, a triple knot; a triple tie.
(a.) Three times repeated; treble. See Treble.
(a.) One of three; third.
(a.) To make threefold, or thrice as much or as many; to treble; as, to triple the tax on coffee.
Example Sentences:
(1) S&P – the only one of the three major agencies not to have stripped the UK of its coveted AAA status – said it had been surprised at the pick-up in activity during 2013 – a year that began with fears of a triple-dip recession.
(2) Compared with cultures from afebrile women, organisms were recovered from 51 (93%) of 55 febrile postpartum women by using the triple-lumen transcervical culture method (P less than .001).
(3) But the Franco-British spat sparked by Dave's rejection of Angela and Nicolas's cunning plan to save the euro has been given wings by news the US credit agencies may soon strip France of its triple-A rating and is coming along very nicely, thank you. "
(4) Liver bloodflow remained unchanged in AS dogs, but hepatic alanine uptake nearly tripled (p less than 0.01) and hepatic glucose production increased by 60% (p less than 0.05).
(5) In experiments using double and triple chamber cultures it was demonstrated that suppressive macrophages from advanced T8-Guérin tumor (diameter 5--6.5 cm) bearing rats produced a dialysable factor which suppressed the killer activity of lymphocytes from non-advanced T8-Guérin tumor (diameter 0.5--0.7 cm) bearing rats, as well as from nonadvanced h 18R tumor bearing rats and from Ehrlich ascites bearing mice, against T8-Guérin ascitic cells and, respectively, against h 18R ascitic and Ehrlich ascitic cells.
(6) The headteacher of the school featured in the reality television series Educating Essex has described using his own money to buy a winter coat for a boy whose parents could not afford one, in a symptom of an escalating economic crisis that has seen the number of pupils in the area taking home food parcels triple in a year.
(7) The function of these triple cones can not be deduced from the behavior patterns of these fishes.
(8) An analysis of the triple helical stabilities of these cleavage site regions as reflected by their imino acid contents fails to yield a correlation between reactivity and triple helical stability.
(9) A total of 50 patients received a cadaveric renal transplant followed by immunosuppression with triple therapy.
(10) From the area between the papillae sensory endings appearing in sections to be either single, double or triple are described.
(11) Blood flows to contralateral cerebral hemispheric structures were relatively unchanged from prehypoxic values, whereas flows to the brainstem and cerebellum nearly doubled and tripled, respectively.
(12) Four separate features could be distinguished in Fe-DNAase-1 digestions of human lymphoblast nuclei: a di-nucleosomal (2N) repeat, a mono-nucleosomal (1N) repeat, a component of "random" DNA, and triple splitting of major peaks.
(13) In a triple tier configuration, females concentrated 66% of their travel on the top tier.
(14) Twenty-two patients with radiologically localised pulmonary tuberculosis underwent one or more broncho-alveolar lavages: 10 patients had a single lavage in the disease area, 11 had two lavages (1 in a healthy zone and 1 in the affected zone) and 1 patient had a triple lavage.
(15) LU, a branch of the London mayor's Transport for London authority, claims that Aslef is seeking triple-time pay and an extra day off for members working on Boxing Day.
(16) The uterine osteosarcoma is the seventh case reported in the world, while it is the second case of synchronous triple primary tumors of the upper female genital tract.
(17) Total body water, extracellular body water, and plasma space were determined using the triple radiotracer technique.
(18) Incubation and heating of the polymers in 1 mM Mn2+ caused the spectral shift reported for the left-handed Z-DNA conformation in the alternating copolymer and the change reported for the triple helix in the homopolymer.
(19) His client-base has tripled since January, and now includes more than half of Shanghai and Beijing's international schools.
(20) A preparation in a special triple bath was drawn through two rubber membranes dividing the strip into three segments.