(1) The DNA of tum- variant P35 was transfected into P815 cell line P1.HTR.
(2) Mutagen treatment of mouse P815 tumor cells produces tum- variants that are rejected by syngeneic mice because these variants express new surface antigens.
(3) We have isolated human and bovine cDNA clones that encode the homologs of the mouse tum- antigen P198.
(4) apparently not to be due to any mutation such as typ, tup, tmp, per or tum.
(5) The diversity of these antigens appears to be very large, like that of the tum- antigens.
(6) Immunization of rats with one C variant (C8) tum- cells did not protect them against either metastases or local growth of the implanted tumours.
(7) This antigenic pattern is similar to that found on teratocarcinoma tum- variants.
(8) Each of these "tum-" variants is rejected in syngeneic mice and stimulates the production of immune memory cells (self-protection).
(9) Mutagen treatment of P815 tumour cells produces tum- variants that are rejected by syngeneic mice because they express new transplantation antigens.
(10) The cells carrying the mutant alleles have impaired tumorigenicity compared with their progenitors due to in vivo induction of a cytotoxic T-cell response specific for tum- antigens.
(11) The drug susceptibility pattern of the strains revealed that there was no significant association of resistance between Tum and streptomycin or rifampicin or ethambutol or ethionamide or isoniazid.
(12) The sequence of this gene and that of two other tum- genes are totally unrelated with each other and with any sequence presently recorded in data banks.
(13) Our results suggest that the procedure of using a mutagen in order to generate tum- variants carrying new transplantation antigens may be generally applicable to cancer cells.
(14) Rumbling tums can be quietened at plenty of places to eat round the estate, until 5.30pm.
(15) Although tum+ clones grew in normal mice, immune mice were able to prevent the growth of tum+ clones with high levels of H-2 antigens.
(16) We have analyzed the effects of high doses of cyclophosphamide (Cy) on primary and secondary antitumor immune response against immunogenic (tum-) variants of Lewis lung carcinoma (3LL) treated in vitro with UV light.
(17) The tum- allele differs from its normal counterpart by a point mutation.
(18) Mongolian gerbils (Meriones unguiculatus) of Tumble Blook (TUM) and Japan Medical Science (JMS) stocks were compared with regard to susceptibility to Leptospira interrogans serovar copenhageni.
(19) The tum- clones are therefore unable to generate tumors in syngeneic mice because they elicit an immune rejection response.
(20) No H-2 antigens were found on the cell surface of the parental BL6 clones, whereas all tum- clones from the BL6T2 line expressed high levels of H-2 antigens.
Tup
Definition:
(v. t. & i.) To butt, as a ram does.
(v. t. & i.) To cover; -- said of a ram.
(n.) A ram.
Example Sentences:
(1) apparently not to be due to any mutation such as typ, tup, tmp, per or tum.
(2) Essentially all mutants (called tup) selected in this way required dTMP for growth in the presence of the two drugs, but none required dTMP in the absence of the drugs.
(3) To achieve a high conception rate, tupping should take place under supervision.
(4) In this study, the composition of the catheter had no bearing on subsequent stricture formation following TUP.
(5) The greatest number of prolapses occurred in an upland flock of greyface ewes mated with Suffolk tups with 50 cases among 700 ewes (7.1 per cent) and the highest prevalence was in an upland Scottish blackface flock of ewes bred with Suffolk tups with 15.2 per cent (35 cases among 230 ewes).
(6) The erythrocyte sedimentation rate (ESR) correlated significantly with the total urinary protein (TUP) in 24-hour urine collections in patients with glomerular disease (p less than 0.05 to p less than 0.001).
(7) The sot1 mutation specifically blocks the uptake of dTMP into tup strains.
(8) [3H]ATP incorporation was Mg2+-dependent, sensitive to ribonuclease and EDTA and resistant to deoxyribonuclease and actinomycin D. There was no incorporation of [3H]UTP or [3H]dTTP and addition of TUP, CTP and GTP did not increase the incorporation of [3H]ATP.
(9) 5.01pm GMT Some MPs’ comments on Twitter: Michael Fabricant (@Mike_Fabricant) No question Andrew Mitchell has tupped the ante considerably.
(10) At puberty, 40 days of age, the excretion of TUP corresponded to the output of alpha2u-globulin.
(11) From 100 to 200 days of age, TUP remained constant while the excretion of albumin steadily increased.
(12) A short description is given of the techniques for percutaneous transhepatic (PTP) and transumbilical (TUP) portal Venous catheterization and their use for direct selective catheterization of the portal vein and its tributaries.
(13) The sot1 mutation maps between rad1 and the centromere of chromosome XVI, and is unlinked to any of the tup mutations.
(14) Facebook Twitter Pinterest A Herdwick ram is prepared for showing at the annual Keswick Tup fair.
(15) Renal function was assessed by daily total urinary protein (TUP), plasma creatinine concentration [(Cr)p] and creatinine clearance rate.
(16) Thereafter, the excretion of albumin and TUP increased markedly whereas alpha2u excretion remained constant.
(17) Thirteen patients with urethral stenoses of different etiopathology underwent TUP with an angioplasty balloon catheter.
(18) After 150--180 days of age, the concentrations of alpha2u and albumin in TUP were approximately equal.
(19) Positive correlations were found between GSC and SBP and TUP.
(20) Because latex rubber catheters have been implicated in urethral stricture formation, the incidence of urethral strictures following transurethral prostatectomy (TUP) and subsequent catheterisation with latex rubber or polyvinyl chloride catheters was compared.