(a.) Not able; not having sufficient strength, means, knowledge, skill, or the like; impotent' weak; helpless; incapable; -- now usually followed by an infinitive or an adverbial phrase; as, unable for work; unable to bear fatigue.
Example Sentences:
(1) Unfortunately, due to confidentiality clauses that have been imposed on us by the Department of Immigration and Border Protection, we are unable to provide our full names and … titles … However, we believe the evidence that will be submitted will validate the statements that we are making in this submission.” The submission detailed specific allegations – including names and dates – of sexual abuse of child detainees, violence and bullying of children, suicide attempts by children and medical neglect.
(2) Consensual but rationally weak criteria devised to extract inferences of causality from such results confirm the generic inadequacy of epidemiology in this area, and are unable to provide definitive scientific support to the perceived mandate for public health action.
(3) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(4) E-RFC enriched for T lymphocytes and depleted of macrophages synthesized considerable DNA in response to stimulation with PHA, but were unable to produce significant bone resorbing activity in tissue culture unless macrophages were re-added to the E-RFC.
(5) Where he has taken a stand, like on gun control after the shootings in Newtown, Connecticut, Obama was unable to achieve legislative change.
(6) A failure to reach a solution would potentially leave 200,000 homes without affordable cover, leaving owners unable to sell their properties and potentially exposing them to financial hardship.
(7) We have therefore been unable to confirm that SV5 may be a major intrathecal immunogen in multiple sclerosis.
(8) The ability of ligand to stimulate its own synthesis and that of its receptor suggests the presence of an autocrine positive feedback loop, however we were unable to break this loop in the breast cancer cells by antibodies that blocked the interaction of TGF alpha with the EGF receptor.
(9) The lymph node cells obtained from the animals 1 day after desensitization were unable to produce MIF in the presence of either antigen.
(10) It happens to anyone and everyone and this has been an 11-year battle.” Emergency services were called to the oval about 6.30pm to treat Luke for head injuries, but were unable to revive him.
(11) Therefore, 31P MR spectroscopy may be unable to quantify the cell fraction of a tumor that has radiobiologic hypoxia.
(12) A temperature-sensitive mutant of Saccharomyces cerevisiae was identified which at the restrictive temperature of 37 degrees C is unable to secrete a number of cell wall-associated proteins and thus resembles previously reported sec mutants.
(13) The enzyme alone, solubilized and free from cytocrome b5 reductase and cytochrome b5, was unable to catalyze the desaturation of stearoyl CoA.
(14) "It will strike consumers as unfair that whilst the company is still trading, they are unable to use gift cards and vouchers," he said.
(15) The data suggest that the hypothalamic beta-E containing neurons were unable to adapt to nicotine's repeated effects on this system.
(16) Analogues of ATP were unable to reactivate K+-ATP channels even in the presence of Mg2+.
(17) PRL, human CG, ACTH, insulin, glucagon, and heat-inactivated TSH were unable to prevent the effect of medium replacement on dopaminergic inhibition of TSH and DA receptor binding.
(18) We were unable to detect IL-4 production by mononuclear cells and CD4+ T cell subsets suggesting that, if it is produced at all, IL-4 is produced in extremely small quantities.
(19) One elderly woman was left alone in the dark for hours unable to find food or drink.
(20) Inexperienced physicians are often unable to immediately identify these translucencies as air enclosures in the intracranial cavity.
Uncapable
Definition:
(a.) Incapable.
Example Sentences:
(1) Both capped and uncapped mRNAs interact directly with eIF-4B to form a stable complex, which can be detected by a simple nitrocellulose filter binding assay.
(2) The naturally uncapped genomic and mRNAs of poliovirus initiate translation by an internal ribosome-binding mechanism.
(3) He said the uncapped scheme provided “an incentive for employers and unions to sign up to unsustainable redundancy entitlements safe in the knowledge that if the company fails the fair entitlements guarantee and the Australian taxpayer will pay for it”.
(4) The aspects of surgical treatment depended on whether the metastases were solitary or multiple, capable or uncapable of radioiodine uptake.
(5) Although uncapable as such to facilitate lordosis behavior the dose of 100 micrograms P rendered the animals responsive to the odor of urine.
(6) Of all the parameters tested for in the questionnaire, those with positive serology differed significantly from the whole population only in that a higher proportion of the positives reported exposure to silo gas and illness after uncapping silos.
(7) When capped pre-mRNA was replaced by uncapped pre-mRNA, complex formation was significantly reduced.
(8) Translation of capped host cell mRNAs is inhibited, whereas translation of uncapped poliovirus mRNA proceeds exclusively.
(9) Expression of this heterodimeric enzyme in E. coli may facilitate the analysis of its functional domains and provide a useful reagent for the specific 5' labeling of uncapped or capped RNA and for enhancing RNA translatability in eukaryotic systems.
(10) Antiserum to estradiol activated both reinitiation, development and completion of meiosis, but the cells matured by estradiol deficit were as a rule uncapable of fertilization and further cleavage.
(11) m7GpppG-capped or -uncapped RCNMV RNA-1 and RNA-2 transcripts were infectious and induced symptoms identical to those of wild-type virus infection when coinoculated on the systemic hosts Nicotiana benthamiana and N. clevelandii, and on the local lesion host Chenopodium amaranticolor.
(12) However, this salt dependence was much less marked in the mammalian reticulocyte extract and, at salt concentrations optimal for translation of normal capped mRNAs, reticulocyte lysates translated uncapped with mRNAs at 30 to 60% the normal efficiency.
(13) Therefore, the exonuclease activity released from ribosomes by high salt extraction was separated from the enzyme(s) that degraded uncapped RNAs.
(14) Similarly, the synthesis of PVS genomic RNA-directed peptides was inhibited by the cap analogue m7G5'ppp5'G, suggesting the presence of a cap structure at the 5' terminus whilst subgenomic RNA encoded products remained unaffected, suggesting an uncapped structure.
(15) Poly(A) less messengers are less active when tested in a wheat germ cell free system and become uncapable to terminate globin chain elongation.
(16) First we give landowners our money – vast amounts of it, uncapped and almost unconditional.
(17) This year the bar on uncapped recruitment has been lowered to include students earning an A and two B grades, meaning a larger number of students able to seek offers from more competitive courses.
(18) However, addition of a 5'-cap to beta-eliminated globin mRNA or satellite tobacco necrosis virus RNA (normally uncapped) increased binding affinity of these mRNAs for eIF-4B and causes binding of these mRNAs to become sensitive to inhibition by m7G5'ppp.
(19) The ApppG-primed precursor mRNAs served as a control (uncapped) in the injection experiments, and their splicing reactions were compared with those of their capped (m7GpppG-primed) counterparts.
(20) Investigation of the influence of various parameters on the ratio of full-length to incomplete products leads to the conclusion that a high fidelity of translation can be obtained provided certain precautions are followed: the use of capped, rather than uncapped, mRNAs at low concentrations, with KCl concentrations about 20 mM above the level that gives maximum incorporation.