(1) Other specific rearrangements also identified were: one translocation, sT5(II;III), and two unc-36 duplications, sDp8 and sDp9.
(2) The uncI gene, the first gene of the unc operon, has been cloned into an expression vector carrying the lambda PRPL promoters in tandem orientation and the gene cI857 coding for the thermolabile repressor.
(3) In addition to mutations in sup-20, other mutations causing muscle defects, such as unc-54 and unc-22 mutations, suppress the hypercontracted phenotype of unc-105.
(4) This protein shares an extended region of sequence similarity, called the POU domain, with the lymphoid-specific transcription factor Oct-2, the pituitary-specific transcription factor Pit-1, and the Caenorhabditis elegans cell lineage gene product unc-86.
(5) Electron microscopy of the replicating molecules, after digestion with restriction endonucleases, showed that the replication fork proceeds exclusively counter-clockwise towards the unc operon.
(6) Unexpectedly, we have found in the course of this work that very high copy numbers of the unc-54 gene lead to a disruption of muscle structure which may result from overexpression of the protein product.
(7) These were recovered from a lambda gt 10 library of DNA from a specially constructed genetic strain containing the unc-43 to unc-31 interval from the BO strain and the rest of the genome from N2.
(8) The allele e675, which possesses a normal amount of myosin but fails to assemble thick filaments, has been shown previously to contain a novel heavy chain of molecular weight 2 X 10(5), shorter by 10(4) than the wild-type (N2) unc-54 gene product.
(9) One isolate contains two separate deletions, each of which affects unc-54.
(10) These results show that the unc-18 gene plays a role in development as well as in the kinetics of ACh metabolism.
(11) The homeo box-containing genes mec-3 and unc-86 are necessary to specify the fate of a defined set of mechanoreceptors in Caenorhabditis elegans.
(12) In unc-deleted cells, these plasmids produced F0 in amounts comparable to those found in normal unc+ E. coli cells, while having only small effects on cell growth.
(13) We conclude that the replication fork usually proceeds counter-clockwise toward the unc operon in the earliest period of replication.
(14) This variant phenotype, designated as uncoupled (UNC), has been stable for more than 100 generations without exposure to the drugs used for selection.
(15) Potential adaptations of an existing instrument (the Duke-UNC Functional Social Support Scale) are demonstrated, and a taxonomy of stages of cancer that would require additional types of social support measures and interventions is outlined.
(16) In particular, the hypodermis surrounding the ventral cord is not the primary focus of unc-3 action (body muscle was excluded in earlier work).
(17) In hermaphrodites, mnDp72 and mnDp73 promoted meiotic X nondisjunction and recombined with an X chromosome in the unc-1-dpy-3 interval at frequencies comparable to that found for X-X recombination; mnDp72(X;IV) also promoted trisomy for chromosome IV.
(18) Two mutant strains, unc-79 and unc-80, show altered responses to these anesthetics.
(19) The principle of this procedure is to mutate P1-transducing phage particles carrying the ATPase genes (Unc (uncoupled) DNA) using the strong chemical mutagen hydroxylamine.
(20) However proton translocation associated with the NADH-menadione reductase activity was prevented by a mutation in an unc gene.
Uncle
Definition:
(n.) The brother of one's father or mother; also applied to an aunt's husband; -- the correlative of aunt in sex, and of nephew and niece in relationship.
(n.) A pawnbroker.
Example Sentences:
(1) This week's unconfirmed claims that Kim's uncle Jang Song Thaek had been ousted from power have refocused attention on the country's domestic affairs; some analysts say Jang was associated with reform .
(2) At a home less than a block away, a man identifying himself as Tamir’s uncle said the boy’s family was not commenting and referred reporters to an attorney.
(3) His maternal uncle is severely retarded and has similar dysmorphic facies.
(4) Acquaintance with a teenaged girl of roughly qualifying age is not essential, but probably helpful, when it comes to appreciating the degree to which Uncle Rupert's views on women, as still reflected in Page 3 , have not progressed since his executives started perving over snaps of their favourite teens.
(5) The ibd for grandparent-grandchild pairs is least affected by recombination, followed by sibs, half-sib, uncle-nephew, and first-cousin pairs.
(6) Another of Milosevic's favourite uncles also killed himself.
(7) I can’t,” says sufi pop singer Rahat Fateh Ali Khan, comparing himself unfavourably to his uncle, the late Pakistani superstar Nusrat Fateh Ali Khan .
(8) He lost contact with his father, a lorry driver, for several years, but says that his mother - aided by his uncle - made it her mission to shield him from the crime and disorder around them.
(9) Marcel's wife, Gertrude, and four children were taken in by Muamba's uncle.
(10) That was one of the advantages of having a gay "uncle" – he took me to gigs.
(11) The road to gaining nearly 1.2 billion monthly active users has seen the mums, dads, aunts and uncles of the generation who pioneered Facebook join it too, spamming their walls with inspirational quotes and images of cute animals, and (shock, horror) commenting on their kids' photos.
(12) Evaluation of family members for presence of the urinary inhibitor factor for thiamine diphosphate phosphoryl transferase revealed abnormal levels in a brother, a maternal uncle, and the maternal grandfather of the patient.
(13) Paul Pogba’s Mr 10% has said that, despite reports linking him to Real Madrid, PSG, Chelsea and Uncle Tom Cobley FC, his client will be staying at Juventus.
(14) Still, he won the vote on a platform against corruption and thousands of cheering supporters welcomed “Uncle Jona” into office.
(15) I'll try to visit Jeffrey when I can and if I have kids in the future I'll tell them the whole story, and I hope that I can introduce them to Jeffrey and their aunts and uncles.
(16) An uncle of one of the crew members from the El Faro says the ship was equipped with modern lifeboats.
(17) And at the same time, speaking to black America, he branded Frazier an Uncle Tom, turning him into an object of derision and scorn.
(18) I had all these brothers and uncles so I understood the nature of men and I didn't go in there feeling all intimidated.
(19) In a four-generation family, chondrodysplasia punctata was found in a boy and one of his maternal uncles.
(20) Alas, Charles could not, any more than his great Uncle Edward VIII in 1936 , take the salary with him on emigration; the duchy is public property.