(1) Other specific rearrangements also identified were: one translocation, sT5(II;III), and two unc-36 duplications, sDp8 and sDp9.
(2) The uncI gene, the first gene of the unc operon, has been cloned into an expression vector carrying the lambda PRPL promoters in tandem orientation and the gene cI857 coding for the thermolabile repressor.
(3) In addition to mutations in sup-20, other mutations causing muscle defects, such as unc-54 and unc-22 mutations, suppress the hypercontracted phenotype of unc-105.
(4) This protein shares an extended region of sequence similarity, called the POU domain, with the lymphoid-specific transcription factor Oct-2, the pituitary-specific transcription factor Pit-1, and the Caenorhabditis elegans cell lineage gene product unc-86.
(5) Electron microscopy of the replicating molecules, after digestion with restriction endonucleases, showed that the replication fork proceeds exclusively counter-clockwise towards the unc operon.
(6) Unexpectedly, we have found in the course of this work that very high copy numbers of the unc-54 gene lead to a disruption of muscle structure which may result from overexpression of the protein product.
(7) These were recovered from a lambda gt 10 library of DNA from a specially constructed genetic strain containing the unc-43 to unc-31 interval from the BO strain and the rest of the genome from N2.
(8) The allele e675, which possesses a normal amount of myosin but fails to assemble thick filaments, has been shown previously to contain a novel heavy chain of molecular weight 2 X 10(5), shorter by 10(4) than the wild-type (N2) unc-54 gene product.
(9) One isolate contains two separate deletions, each of which affects unc-54.
(10) These results show that the unc-18 gene plays a role in development as well as in the kinetics of ACh metabolism.
(11) The homeo box-containing genes mec-3 and unc-86 are necessary to specify the fate of a defined set of mechanoreceptors in Caenorhabditis elegans.
(12) In unc-deleted cells, these plasmids produced F0 in amounts comparable to those found in normal unc+ E. coli cells, while having only small effects on cell growth.
(13) We conclude that the replication fork usually proceeds counter-clockwise toward the unc operon in the earliest period of replication.
(14) This variant phenotype, designated as uncoupled (UNC), has been stable for more than 100 generations without exposure to the drugs used for selection.
(15) Potential adaptations of an existing instrument (the Duke-UNC Functional Social Support Scale) are demonstrated, and a taxonomy of stages of cancer that would require additional types of social support measures and interventions is outlined.
(16) In particular, the hypodermis surrounding the ventral cord is not the primary focus of unc-3 action (body muscle was excluded in earlier work).
(17) In hermaphrodites, mnDp72 and mnDp73 promoted meiotic X nondisjunction and recombined with an X chromosome in the unc-1-dpy-3 interval at frequencies comparable to that found for X-X recombination; mnDp72(X;IV) also promoted trisomy for chromosome IV.
(18) Two mutant strains, unc-79 and unc-80, show altered responses to these anesthetics.
(19) The principle of this procedure is to mutate P1-transducing phage particles carrying the ATPase genes (Unc (uncoupled) DNA) using the strong chemical mutagen hydroxylamine.
(20) However proton translocation associated with the NADH-menadione reductase activity was prevented by a mutation in an unc gene.
Unco
Definition:
(a.) Unknown; strange, or foreign; unusual, or surprising; distant in manner; reserved.
(adv.) In a high degree; to a great extent; greatly; very.
(n.) A strange thing or person.
Example Sentences:
(1) In recent years the auditory brainstem evoked response (BSER) has become an established aid in assessing hearing in unco-operative subjects.
(2) The test heat treatment led to neurological complications, ranging from unco-ordinated use of the forelegs to paralysis of both forelegs.
(3) Using it on young children which are unco-operative the Auto-Refractor is not as sufficient as we hoped it to be.
(4) The former editor of the New York Times, Bill Keller, is the target of special ire for his allegedly unco-operative attitude, described as "a moral pygmy with a self-justifying streak the size of the San Andreas fault".
(5) The managers' efforts to identify unmet need were often piecemeal and unco-ordinated, and this may have been, in part, because managers were facing difficulties in meeting existing demands for services.
(6) Pregnancy outcome improved markedly in the latter years, possibly owing to non-exposure to warfarin, less immunosuppression, and improvement in neonatal care, and four of the five mothers who suffered deterioration in renal function were notoriously unco-operative in their medical care.
(7) The uncal or the unco-parahippocampal branches of the anterior choroidal artery were divided into rostral and caudal; the former were present in 70.6%, and the latter were present in 94.1%.
(8) The use of Ketalar as a general anesthetic in dental treatments particularly in extractions of unco-operative children of 2-5 years was studied.
(9) The existence of co-operation between species has been cast as a problem to the selfish-gene view of evolution: why does co-operation persist, when it would seem that individual selection should favor the unco-operative individual who exploits the co-operative tendencies of its partner and gives nothing in return?
(10) At the onset of purposeless, unco-ordinated movements of the entire body, blood samples were obtained to determine the CNS excitation-threshold plasma concentration (ETPC) of laudanosine.
(11) The results indicate that changes in blood-flow patterns and loss of marginal definition of basal vessels are unreliable signs of left-sided insufficiency in old patients or in unco-operative patients, in the presence of a high diaphragm and in the supine position.
(12) A method for securing nasoenteric tubes in the unco-operative patient is presented.
(13) A series of 40 patients with degnerative discopathy was effectively treated to means of trans-unco-discal approach, which is a combined anterior and lateral approach to cervical discs.
(14) The author of that report, Graham Badman, called for "authoritative social work practice" whereby social workers actively and robustly challenged unco-operative or violent clients.
(15) The uncal or the unco-parahippocampal branches of the internal carotid artery, which originated 1.4 to 4.2 mm from its bifurcation site, existed in 58.8%.
(16) The electron spin resonance spectrum, g 4.25, and the low molar relaxivity, 473m(-1).s(-1), of water H(+) suggest the presence of high-spin Fe(III) unco-ordinated to water in the enzyme.
(17) Minor neurological symptoms were observed one day after 75 min at 42.3 degrees C. The incidence and severity of the neurological symptoms (ranging from unco-ordinated use of the forelegs to paralysis) increased with increasing temperature and duration of the hyperthermic treatment.
(18) Vigorous grunts of approval came from Joe Rukin (video) , national co-ordinator of Stop HS2 who was wrestling with the elephant's unco-operative generator.
(19) CNIL also criticised the company for being unco-operative in its responses to queries from the commissioners.
(20) Like a rich country fruit cake, Kidnapped is seasoned throughout with handfuls of dialect words, "ain" (one), "bairn" (child), "blae" (cheerless), "chield" (fellow), "drammach" (raw oatmeal), "fash" (bother), "muckle" (big), "siller" (money), "unco" (extremely) , "wheesht!"