(a.) Not differentiated; specifically (Biol.), homogenous, or nearly so; -- said especially of young or embryonic tissues which have not yet undergone differentiation (see Differentiation, 3), that is, which show no visible separation into their different structural parts.
Example Sentences:
(1) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(2) Macrophages, undifferentiated fibroblasts and highly differentiated fibroblasts can be observed.
(3) Carcinomas exhibiting atypical behavior are characteristically undifferentiated and aggressive.
(4) Because of its potential significance in human lung cancer, we investigated the expression of the CYP1A1 structural gene in 24 established human lung cancer cell lines including 15 non-small cell (eight adenocarcinomas, three large cell undifferentiated carcinomas, two bronchioloalveolar cell carcinomas, and two squamous cell carcinomas) and nine small cell lung carcinomas.
(5) All 51 undifferentiated NPCs contained significant numbers of EBV-genome copies per cell.
(6) Unfortunately, it does not contain a population of undifferentiated stem cells to supply the necessary healthy neurons.
(7) The anterior division can be further parcellated into dorsal, lateral, and ventral areas, and each of these areas, along with the posterior division, can be thought of as containing more-or-less discrete nuclei embedded within a relatively undifferentiated region.
(8) In undifferentiated glioblastomas, the reverse situation was observed, no SS receptors were found (0 of 14) but EGF receptors were present in a majority of tumors (8 of 14).
(9) The human epidermal growth factor receptor (hEGF-R) was introduced into murine P19 embryonal carcinoma (EC) cells, which do not express endogenous EGF-R. Undifferentiated stable P19 EC transfectants containing multiple copies of the hEGF-R complementary DNA were isolated.
(10) However, the tip cells are slow to differentiate, and hence immature fruiting bodies contain a small population of undifferentiated tip cells.
(11) We report on a patient with AL, which showed a very rapid switch from the lymphoblastic phenotype exhibited at presentation to a myelomonoblastic one, appeared at first relapse, and lastly progressed to an undifferentiated leukemia in the terminal phase.
(12) The pathologic diagnosis was rhabdomyosarcoma in 75% of cases, yolk sac tumor in 13% of cases, malignant mesenchymoma in two cases, clear cell carcinoma in two cases, and undifferentiated sarcoma in one case.
(13) Of 28 rats given 0.15 mg of 1,6-DNP, 21 (75%) developed squamous cell carcinomas, 2 (7%) developed undifferentiated carcinomas, and 2 (7%) had squamous metaplasias in the lung by 72 weeks.
(14) A case of large cell undifferentiated adenocarcinoma of the lung was complicated by an aggressive clinical course and documented placental metastases.
(15) In anurans, the oculomotor neurons receive a variety of visual, somatic, and vestibular afferents and appear relatively undifferentiated, whereas the nInt appears more developed.
(16) In previous specimens, solid undifferentiated carcinoma was absent or was a minor pattern.
(17) There was a nonsignificant trend toward higher MHPG levels in paranoid schizophrenic patients in comparison with patients who had undifferentiated schizophrenia.
(18) The process from the first undifferentiated stage to the second predifferentiated stage with well-developed ER and Golgi apparatus requires both collagen gels and hormones.
(19) The possibility of preventing or influencing the course of these diseases by vaccination has been advocated for a number of years [Epstein, 1976], especially in the case of undifferentiated nasopharyngeal carcinoma, which is the most common tumour of men in southern China and is prevalent in other specific regions; it therefore represents a major world cancer problem [Shanmugaratnam, 1971].
(20) Ultrastructurally, the tumor cells were composed principally of undifferentiated mesenchymal cells, and contained prominent pools of glycogen in the cytoplasm.
Uniform
Definition:
(a.) Having always the same form, manner, or degree; not varying or variable; unchanging; consistent; equable; homogenous; as, the dress of the Asiatics has been uniform from early ages; the temperature is uniform; a stratum of uniform clay.
(a.) Of the same form with others; agreeing with each other; conforming to one rule or mode; consonant.
(a.) A dress of a particular style or fashion worn by persons in the same service or order by means of which they have a distinctive appearance; as, the uniform of the artillery, of the police, of the Freemasons, etc.
(v. t.) To clothe with a uniform; as, to uniform a company of soldiers.
(v. t.) To make conformable.
Example Sentences:
(1) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.
(2) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
(3) Mendl's candy colours contrast sharply with the gothic garb of our hero's enemies and the greys of the prison uniforms – as well as scenes showing the hotel later, in the 1960s, its opulence lost beneath a drab communist refurb.
(4) Another, discussing public attitudes towards the police, said: "I've lost count of [the number of] people who said: 'It's only cos you've got a uniform … if you didn't have the uniform on, I'd come and fuck you and this, that and the other … I hope your wife dies of cancer and your kids die of cancer.'"
(5) The cells were taken from cultures in low-density balanced exponential growth, and the experiments were performed quickly so that the bacteria were in a uniform physiological state at the time of measurement.
(6) The age distribution was not uniform as age group 0 to 4 included more children than age groups 5 to 9 and 10 to 14.
(7) Essential characteristics of the composite bone cement included a homogeneous and uniform fiber distribution, and a minimal increase in apparent viscosity of the polymerizing cement.
(8) Ejection fraction, %deltaD, and Vcf by LAO cineangiograms and echo were uniformly higher than corresponding measurements from RAO angio, and were often normal in the presence of other indicators of significant left ventricular dysfunction.
(9) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(10) A study of cell proliferation in different regions of axolotl embryos has shown a rather uniform distribution of the S phase and mitotic indices in the animal half of the early and midgastrulae.
(11) The absence of uniform definitions prevents meaningful intersystem comparisons, prohibits explorations of hypotheses about effective interventions, and interferes with the efforts of quality assurance.
(12) The beads enable us to examine several aspects of the adhesion process with particles having uniform properties that can be varied systematically.
(13) said Wanis Kilani, a uniformed rebel driving a pickup truck with a machine-gun mounted on the back.
(14) In contrast, sporoblasts and budding and free sporozoites in mature oocysts were labeled uniformly on the outer surfaces of their plasma membranes, indicating a uniform distribution of CS protein on these membranes.
(15) His bracelets and his hair, neatly gathered in a colourful elasticated band, contrast with his unflashy day-to-day uniform of checked shirts, jeans or cheap chinos and trainers.
(16) RCA-1, which is specific for D-galactose, showed patchy fluorescence on the basal and distal portions of the outer segments of the cones and rods, whereas neuraminidase-treated sections had uniform fluorescence throughout the tissues.
(17) Previous experiments had demonstrated that the receptors for the lectins soybean agglutinin (SBA), wheat germ agglutinin, concanavalin A and Lens culinaris agglutinin all were relatively uniformly distributed on both myoblasts and myotubes, and that SBA receptors were capable of rapid redistribution on myotubes but not myoblasts at 4 degrees C (Sawyer & Akeson, 1983).
(18) Hence the aggregation inhibition produced by amphiphilic phenylalkylamines and phenylalkanoles is not due to a uniform metabolic effect of both classes of derivatives.
(19) The colors of mixtures of dental opaque porcelains and modifiers were measured with use of the CIE L*a*b* uniform color space.
(20) Although there is no reliable symptom or sign during the latent period, abdominal pain occurs almost uniformly and Kehr's sign is quite common.