(v. t.) To make unsuitable or incompetent; to deprive of the strength, skill, or proper qualities for anything; to disable; to incapacitate; to disqualify; as, sickness unfits a man for labor; sin unfits us for the society of holy beings.
(a.) Not fit; unsuitable.
Example Sentences:
(1) An additional 1.3% of the persons studied needed this operation, but were unfit for surgery.
(2) In unfit patients with advanced disease, palliation from the use of radiotherapy and Celestin tube insertion were poor.
(3) He was first deemed medically unfit to be detained in October, but has remained in custody.
(4) These people would be out of their depth in a paddling pool, and couldn’t be more unfit to run a modern political party.
(5) There were no significant differences between fit and unfit dogs for post exercise plasma concentrations of aspartate aminotransferase, white blood cell count or total protein, although the unfit dogs showed a tendency towards higher values.
(6) He has, however, refused to testify, invoking his right to remain silent, while his lawyer has insisted his client is “insane” and therefore unfit for trial.
(7) He was later ruled unfit to stand trial on physical and mental grounds.
(8) Extra-anatomic bypass grafting has been used as treatment for patients with aorto-iliac disease who were considered unfit for aortic surgery.
(9) Our findings suggest that for patients with stage I endometrial cancer who are unfit for surgery, intracavitary low-dose-rate radiation therapy alone is an effective alternative treatment with a low risk of complications.
(10) It’s extraordinary that you can continue to make law when you are unfit to face it.
(11) It is a simple and effective procedure with minimal complications, and it is especially recommended for those patients who are medically unfit for general anaesthesia.
(12) There were 10 deaths within a month of operation (0.9%), 9 of these patients having been exceptionally old and unfit.
(13) Only 69.3% were declared fit and the overall unfit rate was 22.1%.
(14) He was freed by Jack Straw, the home secretary, on the grounds that medical experts said he was unfit to stand trial.
(15) This could happen if the official receiver thinks that your conduct has been 'unfit'.
(16) A motion brought by Britain’s Ukip, France’s Front National, and Italy’s 5 Star movement described Juncker as unfit to lead the EU executive because of his track record in Luxembourg.
(17) Variant 2 is limited to high 4-PA concentrations, being unfit in low ones for overestimating the data.
(18) In 1949 it was estimated that around 2 million homes were unfit for human habitation, too expensive to repair and earmarked for demolition.
(19) Universities are badly failing students with unfit teaching and old-fashioned methods and will have to radically modernise lectures and facilities if they want to raise fees, according to the Conservatives' spokesman on higher education.
(20) One man had his doctor's testimony, affirming he had a deformed ankle, thrown out, only to be dismissed as unfit from the army two years later, over the same ankle.
Unfix
Definition:
(v. t.) To loosen from a fastening; to detach from anything that holds; to unsettle; as, to unfix a bayonet; to unfix the mind or affections.
(v. t.) To make fluid; to dissolve.
Example Sentences:
(1) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(2) In the second group, a tibial cortical bone graft was detached and refixed with Silar in 12 rats and left unfixed in eight.
(3) Unfixed cells treated with the antiserum had localized areas (capping) of intense membrane fluorescence, whereas fixed cells had bright uniform membranous fluorescence.
(4) The mean activity of lactate dehydrogenase (LDH) in hepatocytes near the central vein region of unfixed sections of mouse liver was determined and compared with 3 different histochemical methods: conventional method, polyvinyl alcohol (PVA) method, and gel film method.
(5) Enzyme activities in sections of fixed corneas were minimal in comparison with those in cold microtome sections of unfixed material revealed particularly with the technic of semipermeable membranes which is to be preferred.
(6) The requirement for unfixed tissue is a major drawback in the use of immunohistochemistry for the diagnosis of inflammatory and neoplastic disease.
(7) The redistribution and internalisation of two different lectin-binding sites on the same cell was investigated electron microscopically on unfixed rat liver cell cultures.
(8) A new staining technique was employed using acridine orange to differentially stain DNA and RNA in unfixed cells made permeable to the dye and other reagents by treatment with detergent at low ph.
(9) Unfixed kidney pieces or kidney pieces fixed in 4% formaldehyde were embedded in the hydrophilic polyhydroxy aromatic resins LR-Gold and LR-White, following dehydration in up to 70% ethanol, 90% ethanol or 100% ethanol.
(10) The use of unfixed and undecalcified cryostat sections of mouse knee joints is described for the study of enzyme histochemical reactions.
(11) Cell fixation after PMA treatment did not abolish this stimulatory activity, which could be transferred by supernatants from unfixed cells; exogenous interleukin-1 did not mimic the activity.
(12) 2) TH-IR nerve fibers could be detected in unfixed tissue if the sections were post-fixed with aldehydes by the use of a two-step fixation process related to a sudden change of pH.
(13) Contraction damage occurring when longitudinal frozen sections of fresh unfixed muscles are thawed on microscope slides has limited histological examination of this tissue mainly to cross sections.
(14) A panel of 14 monoclonal antibodies (McAb) against hematopoietic cell surface antigens was applied on mononuclear blood or bone marrow cells from 40 cases of acute leukemia in order to compare immunoenzymatic staining (IE) (alkaline phosphatase) of fixed cells with immunofluorescence staining (IF) of unfixed suspended cells.
(15) Unfixed metaphase chromosome preparations from human lymphocyte cultures were immunofluorescently labelled using antibodies to defined histone epitopes.
(16) An antisperm antibody enzyme-linked immunosorbent assay (ELISA) that uses whole unfixed sperm and detects immunoglobulin G (IgG) and IgA antibodies in serum was developed.
(17) A nonisotopic, in situ hybridization procedure is described for detecting Epstein-Barr viral (EBV) DNA in cytopreparations of pepsin-digested, unfixed cells in less than 3 hours.
(18) The localization and activity of the lysosomal enzyme, N-acetyl-beta-glucosaminidase, has been studied in unfixed frozen sections of tissues from normal and hemorrhaged rats with the use of a modified postcoupling technique.
(19) The pulmonary artery of unfixated human heart-lung specimens was banded by placing a Dacron tape around the artery and securing the tape with a 5.0 Prolene suture at selected circumferences.
(20) An immunofluorescence study using unfixed cryostat sections of rat pituitary glands was carried out on sera from 34 patients with Hashimoto's thyroiditis, 28 patients with Graves' disease, 10 patients with thyroid adenoma and 50 healthy subjects.