(v. t.) To open the folds of; to expand; to spread out; as, to unfold a tablecloth.
(v. t.) To open, as anything covered or close; to lay open to view or contemplation; to bring out in all the details, or by successive development; to display; to disclose; to reveal; to elucidate; to explain; as, to unfold one's designs; to unfold the principles of a science.
(v. t.) To release from a fold or pen; as, to unfold sheep.
(v. i.) To open; to expand; to become disclosed or developed.
Example Sentences:
(1) The estimated DNA compaction ratio (approximately 3-fold) is consistent with a significant degree of nucleosome unfolding in the hyperstimulated BR genes.
(2) This formalism allows resolution of the intrinsic protein folding-unfolding parameters (enthalpy, entropy, and heat capacity changes) as well as the ligand interaction parameters (binding stoichiometry, enthalpy, entropy, and heat capacity changes).
(3) The kinetics of inactivation of the Mg(2+)-containing enzyme in 8 M-urea at higher temperatures suggest a partially unfolded Mg-A-B* dimer intermediate with 50% activity, followed by irreversible inactivation coincident with the appearance of unfolded monomer.
(4) When RNAase is partially unfolded Au(III) causes oxidation of methionines to the sulphoxide, and leads to almost complete unfolding (at molar equivalent ratios).
(5) In the context of a simplified diamond lattice model of a six-member, Greek key beta-barrel protein that is closely related in topology to plastocyanin, the nature of the folding and unfolding pathways have been investigated using dynamic Monte Carlo techniques.
(6) The efficiency of energy transfer between probes attached to residues 1 and 15 in the reduced state is higher than that found for the same pair of sites in the native state or reduced unfolded (in 6 M Gdn.HCl) state.
(7) Coombs's theory of data (1952, 1964) and his unfolding theory of preferential choice (1950, 1964) provided the conceptualization of metacognition in this psychophysical task context.
(8) Yet what has been unfolding in the past 15 months or so should make even the most ardent pro-European think about an orderly mechanism for making member states exit: the euro crisis and, less obviously, Hungary's backsliding from liberal democracy to a soft form of authoritarianism, or what an American paper recently called " Lukashenko lite ".
(9) Circular dichroism studies show that the conformation of each subunit is unusually resistant to change in 6 M guanidine HC1 at 25 degrees C. This suggests that exposure of the epitope by dissociation requires minimal or no unfolding of subunits.
(10) The data relative to the guanidine-induced unfolding show a sigmoidal increase of the distribution width, which is due to the transition of the protein structure from the native to the random-coiled state.
(11) The data suggest that the assessment of early trauma needs to employ a variety of measures, especially those which are related to the unfolding skills appropriate for the particular age group studied.
(12) In contrast to the biphasic unfolding of the wild-type nuclease, the unfolding of the mutant is represented by a single-phase reaction, indicating that the biphasic unfolding for the wild-type protein is caused by cis-trans isomerization about the prolyl peptide bond in the native state.
(13) 4) The unfolded map diagnosis with apical display obtained from long-axis tomogram was useful to diagnose left anterior descending coronary (LAD) lesion, which improve not only the sensitivity of LAD but also specificity of right coronary artery single vessel disease.
(14) The replacement of Arg171 by Tyr stabilizes the enzyme against thermal inactivation and unfolding.
(15) These findings and the dense structure of the scleral spur suggest that in monkey eyes, and at least in some human eyes, contraction of the ciliary muscle causes unfolding of the trabecular meshwork, not so much through the movement of the scleral spur as by movement of the interconnecting trabecular beams and fibers.
(16) The principal parameter under scrutiny was the denaturing or unfolding effects caused by the interaction of the protein with the adsorptive surfaces in each assay system.
(17) For here we see the depravity to which man can sink, the barbarity that unfolds when we begin to see our fellow human beings as somehow less than us, less worthy of dignity and life; we see how evil can, for a moment in time, triumph when good people do nothing."
(18) In contrast, import of the surface-bound unfolded precursor requires ATP, but no potential; it is accompanied by a refolding inside the mitochondria.
(19) These experiments show that yeast cells can activate a transcription factor that stimulates expression of a nuclear gene in response to the accumulation of unfolded proteins in another cellular compartment.
(20) In the present study, the reversibility of the unfolding-refolding process induced by guanidine hydrochloride was investigated for the intact protein and the isolated domains.
Unroll
Definition:
(v. t.) To open, as what is rolled or convolved; as, to unroll cloth; to unroll a banner.
(v. t.) To display; to reveal.
(v. t.) To remove from a roll or register, as a name.
Example Sentences:
(1) Cerebral angiogram displayed a contralateral shift and an unrolling of the anterior cerebral artery, a lateral stretch of middle cerebral artery, a downward stretch of anterior choroidal artery and a tumor stain fed by the Heubner artery.
(2) The red carpets are being unrolled, the paparazzi are installing their stepladders, the dressmakers are rushing their schmutters to the airport – the Cannes film festival is finally upon us.
(3) More than 80 percent required correction in such things as opening the package, determining the outside of the condom, unrolling the condom to the base of the penis, and expressing air from the space at the tip of the penis.
(4) The detergent removes the membrane and many axonemes unroll, always in an organized fashion so that doublets follow one another in sequence, according to the enantiomorphic form of the cilium.
(5) This was going to be the viewpoint, and it began to unroll like a cinema film.
(6) The Republican governor of Alabama, Robert J Bentley, has chosen this day for his inauguration to his second term and a parade is planned; a red carpet is being unrolled on the capitol steps.
(7) The area of the unrolled myelin sheet of internodes of myelinated fibers (MF) of peripheral nerve is thought to be determined by axonal caliber and internodal length.
(8) It went on to tour in New York, Chicago, Ottawa and Berkeley, and Soleri soon became a regular feature on the international lecture circuit, staging sell-out performances where he would theatrically unroll his great drawings across the stage.
(9) Blow me, but in 15 days' time, a bright green carpet will be unrolled in Leicester Square and Franny Armstrong , now 35, better travelled but just as singleminded, will trip down it in the company of A-list celebs, to a specially constructed solar-powered cinema.
(10) The internal organization of this axon population was analysed by topologically transforming the cortical surface from its in situ cylindrical form into an unrolled (flattened) map.
(11) Standing on two feet, barefoot with fixed upright posture; 2. dynamic unrolling of the bare-footed human footsole with constant walking speed.
(12) I believe that we are best as a party when we lead with our principles and not according to the polls.” Karol said O’Malley did not appear to be unrolling a campaign for the vice-presidency.
(13) The carotid angiogram showed an unrolling of the pericallosal artery, but no findings of space taking lesions.
(14) A single change allows the heart to be "unrolled" into a plane for roentgenographic study of injected coronary arteries.
(15) Gaze out on to the silvery surf unrolling behind your cruise liner?
(16) These observations are expressed in a schematic summary of the trajectories of olfactory bulb efferents as they appear in the unrolled map and in the more standard ventral view of the hamster brain.
(17) Now that the weather has finally brightened up, we should be unrolling the picnic blankets.
(18) "They are very well-known as images," said Gallagher, "but they have not been brought together ever before, and we want to show the unravelling and unrolling of an entire career."
(19) The public relations effort unrolled by the State Department also ventured into legal terrain, according to the report.
(20) The government unrolled a package of measures that would give career guidance and work placements to all unemployed people under 25 in some of the poorest suburbs; there would be tax breaks for companies who set up on sink estates; a €1,000 (£675) lump sum for jobless people who returned to work as well as €150 a month for a year; 5,000 extra teachers and educational assistants; 10,000 scholarships to encourage academic achievers to stay at school; and 10 boarding schools for those who want to leave their estates to study.