(a.) Not happy or fortunate; unfortunate; unlucky; as, affairs have taken an unhappy turn.
(a.) In a degree miserable or wretched; not happy; sad; sorrowful; as, children render their parents unhappy by misconduct.
(a.) Marked by infelicity; evil; calamitous; as, an unhappy day.
(a.) Mischievous; wanton; wicked.
Example Sentences:
(1) But what they take for a witticism might very well be true; most of Ellis's novels tell more or less the same story, about the same alienated ennui, and maybe they really are nothing more than the fictionalised diaries of an unremarkably unhappy man.
(2) Unless psychic rehabilitation is undertaken in tandem with physical rehabilitation, a spinal cord-injured patient is likely to become an unhappy social recluse or denizen of a chronic care facility, rather than an independent productive member of his community.
(3) Along the way, he fathered a child at 20 and immediately turned his back on her (they are now reunited), had a brief and unhappy marriage to the broadcaster Carol McGiffin and a series of frenetically unsatisfying relationships.
(4) I remind him that he had been unhappy with the penalty awarded to Barcelona in the Champions League game at Wembley last season, and he smiles.
(5) George Osborne may well end up in the unhappy position of trying to convince the public, in a haunting echo of the 2010 campaign, that he is still the man to bring the nation's finances back into balance by the end of the next parliament.
(6) Photograph: Rex If they are still unhappy they can go to the free Financial Ombudsman Service (FOS), which resolves disputes between consumers and financial firms, although the PAC raised concerns about the service’s backlog of cases.
(7) Three months later the mothers appeared to be interacting normally with their infants, but they expressed feelings of unhappiness that persisted until the infants reached 9 months of age.
(8) So we're all very unhappy about it, but what can we do?
(9) The church excommunicated him in 1901, unhappy with his novel Resurrection and Tolstoy's espousal of Christian anarchist and pacifist views.
(10) He said Abbott was reflecting the “unhappiness we all have with what was a big error”.
(11) The distance to the original venue was around 50 miles and the manager, who was unhappy with the scale of travel on last summer’s US tour, vetoed having to make the round trip.
(12) I don't think she would have been unhappy for songs to be published."
(13) The academic, one of the country’s leading experts on the drug, is particularly unhappy with the British Medical Journal (BMJ), which has run well-publicised articles by two critics of statins that he argues are flawed and misleading.
(14) The house flourished but the marriage was bitterly unhappy and ended in divorce.
(15) "Unable to get petrol yesterday and missed a full day's work which will be unpaid, very unhappy," said one from Rickmansworth, Hertfordshire.
(16) Splenectomy could gave a role in producing these unhappy results.
(17) He is reported to have expressed unhappiness at his own pending deployment and of US troops being responsible for the killing of fellow Muslims in Iraq and Afghanistan.
(18) The results, broadcast by Seven News on Wednesday, showed voters were also deeply unhappy with the performance of the Labor leader, Bill Shorten, and indicated that Turnbull enjoyed a strong lead as preferred prime minister.
(19) He says he was unconfident and largely unhappy at school.
(20) But the role opened my eyes to certain aspects of online gaming, such as harassment, abuse, threats and even stalking, and in many ways, it is an unhappy experience that I wish I could undo.
Unsuitable
Definition:
Example Sentences:
(1) Conventional procedures for the isolation of uncontaminated polysomal RNAs which rely on sucrose density centrifugations are laborious and unsuitable for large scale isolations.
(2) However, since peptide ligands are usually unsuitable for development as potent orally active long-duration therapeutic agents, considerable research effort is being directed to the development of non-peptidal ligands.
(3) This technique can be used to treat fractures unsuited for conventional rods.
(4) Normal biomarkers are inherently unsuitable in a positive search for disorder; instead one must either use abnormal markers or be prepared to search negatively, i.e., to look for and somehow validate the rare absence of a normal marker.
(5) Seven patients judged unsuitable for an operation were treated with an aggregated allogeneic antigen.
(6) Five percent of the forceps biopsies were unsuitable for examination; all excision biopsies were of good quality.
(7) These results led to the conclusion that the IFAT screening procedure, as carried out, was unsuitable for the purposes intended.
(8) These results indicate that the 'Imotest' is significantly less sensitive than the Mantoux test and is unsuitable for use as a diagnostic or screening test.
(9) In the courts the remarks of non-specialist qualified persons can lead to wrong decisions as can either unsuitable or wrong evidence.
(10) The carboxamide group is thus unsuitable as was postulated for raising antibodies which recognize the peptide bond.
(11) Two kidneys (Group 3), deemed unsuitable for transplantation, were perfused for 24 hours with perfusate swished with unwashed sterile gloves.
(12) We conclude that s-creatinine and creatinine clearance are unsuitable measures of glomerular function during high-dose cisplatin treatment.
(13) Due to the large variations within and between days, the estimation of unconjugated oestriol in plasma might be unsuitable as a substitute for the estimation of urinary conjugated oestriol in the supervision of complicated pregnancies.
(14) The anterior superior iliac crest, the usual donor site for cortico-spongy bone grafts is unsuitable for the removal of large quantities of spongy bone.
(15) At this stage any attempt at definitive removal of diseased tissue would necessarily result in a larger dural defect at a time when local disease and systemic illness present unsuitable conditions for reparative procedures.
(16) Ultrastructural analysis indicated that Bands 2 and 3 were composed predominantly of membranes, although Band 3 was contaminated with mitochondria; Band 1 and the gradient pellet contained insufficient material and were unsuitable for ultrastructural analysis.
(17) Whilst this sensitive immunological test increases the yield of carcinomas, the high false positive rate makes it unsuitable for population screening for colorectal cancer in its present form.
(18) Unfortunately, a large number of potential compounds are unsuitable for use in dentifrices because they lack "substantivity", produce undesirable side-effects, or are incompatible with toothpaste ingredients.
(19) In this study, we have conducted a systematic investigation of various aspects of cell viability and function of isolated hepatocytes stored at 4 degrees C for 24 and 48 hr in either University of Wisconsin solution or Hanks' HEPES buffer, a control solution clinically unsuitable for organ preservation.
(20) It is concluded that heparin may be given intravenously in normal saline with benzylpenicillin, ampicillin, or methicillin but several other antibiotics were found to be unsuitable for concurrent infusion with heparin.