(a.) Not kind; contrary to nature, or the law of kind or kindred; unnatural.
(a.) Wanting in kindness, sympathy, benevolence, gratitude, or the like; cruel; harsh; unjust; ungrateful.
Example Sentences:
(1) Clearly, therefore, image is everything, especially in a world that can still be unkind to geeky people venturing out in public wearing their latest invention.
(2) You know, I don't mean to be unkind but I think you should put your phone down because you're just being a dick, really, just enjoy the gig because it's a better … it's a dick job, filming the show.
(3) Somehow, British zoos still enjoy a protected, deeply forgiving space, in a nation of pet lovers, for manifest unkindness towards animals.
(4) Mottling of teeth can have significant psychological impact on patients--particularly on adolescents, who may be subjected to much unkind teasing.
(5) This agenda might unkindly be described as systematic anti-liberalism with a seasoning of resentment and paranoia.
(6) The place to go in parliament for unkind evaluations of Miliband’s legacy is the Labour benches.
(7) But sometimes the revelations come fast, and when they do, they are usually particularly unkind.
(8) But clearly results have been immeasurably more crushing and unkind than I could ever have feared.
(9) I'd forgotten quite how swathey it was, rather unkindly imagining literary novelists and Big Thinkers in stripped-pine north London would be over-represented.
(10) And while Özil is allowed to have a poor game, it is hard to block out the memory of those unkind whispers on his departure from Madrid about his conditioning and stamina.
(11) Irony Steven Friedman , director of Rhodes and Johannesburg universities, said: "It has to be said that one of the great ironies of the debates about how we should receive Barack Obama is that, while a lot of South Africans are very sympathetic to him because he's the first African-American president, "I don't think that it's unkind to say that he's done absolutely nothing for this continent.
(12) I got to know him quite well after that and never once did I see him being unkind or inconsiderate to people.
(13) The academic Steve Bruce once unkindly stated: "When Ulster Protestants talk about being British, it is clear that the Britain they have in mind is no more recent than the 1950s, and often their points of reference are positively Victorian."
(14) Unkind though it is to remind him of his own cruel witticism aimed at Gordon Brown when he was at his weakest, there is now more than something of Mr Bean about Dr Cable.
(15) If modern life is unkind to our mental health, it’s no doubt in part because so many young people fear that admission of vulnerability will affect their employment, or their relationships, at a time when their futures are already far less clear than those of their parents.
(16) The results of this study lend weight to the argument that those who wish to have their facial abnormalities reduced may be accurately reporting that society is unkind to them.
(17) History tends to be unkind to those who embrace the evil practices of those they once denounced.
(18) Ruben Loftus-Cheek provided the visitors’ second, sliding a pass through the centre for Oscar to collect before McFadzean was aware of his presence, the finish crisply clipped into the far corner from an unkind angle.
(19) The crime also inspired a Bollywood film – on which MacKeown was never consulted, but later said “was not unkind” in its depiction of her daughter.
(20) On Thursday, as one SNP fundraising leaflet unkindly but accurately put it, the party has a chance to “complete the set”, making it the dominant force in all areas of Scotland’s political life.
Unwind
Definition:
(v. t.) To wind off; to loose or separate, as what or convolved; to untwist; to untwine; as, to unwind thread; to unwind a ball of yarn.
(v. t.) To disentangle.
(v. i.) To be or become unwound; to be capable of being unwound or untwisted.
Example Sentences:
(1) Unlike cisplatin, bis(platinum) complex binding does not unwind supercoiled DNA.
(2) Of the 47 compounds that were positive or equivocal in the alkaline unwinding assay, only carbon tetrachloride and prednisolone were negative in the mouse lymphoma assay, while 12 of the 19 compounds that were negative in the alkaline unwinding assay were positive in the mouse lymphoma assay.
(3) As suggested from the high level of sequence similarity of these viral proteins with the recently described superfamilies of helicase-like proteins (3-5), the NTBM-containing cylindrical inclusion (CI) protein from plum pox virus (PPV), which belongs to the potyvirus group of positive strand RNA viruses, is shown to be able to unwind RNA duplexes.
(4) This limited unwinding of heterologous duplex DNA, termed heterologous unwinding, was detected within 30 seconds and reached a steady state within a few minutes.
(5) Comparison of the superhelix densities obtained by both methods permits a calculation of an unwinding angle for ethidium.
(6) The exposure of the cells from mussel haemolymph and from mouse L1210 to a genotoxic compound such as dimethylsulfate results in DNA damage and consequently in a reduction of the unwinding time.
(7) As for unwinding, the rituals of it give a satisfying end to the shape of my day.
(8) Chromosome replication appears to initiate in E. coli when the dnaA boxes in oriC become filled with DnaA protein, which could simultaneously mediate both the unwinding of the origin for the start of polymerization and the attachment of oriC to the cell envelope (Bramhill and Kornberg, 1988; Løbner-Olesen et al., 1989; Pierucci et al., 1989).
(9) The protein fraction containing the 93 000 dalton protein had considerable unwinding activity, depressing the melting temperature of poly(dA-dT) by 39 degrees C. The protein fraction containing the bulk of the 35 000 dalton protein did not have unwinding activity.
(10) The required cellular protein may be a eukaryotic single-stranded-DNA-binding protein (SSB), since unwinding of the template is also observed when Escherichia coli SSB is substituted for the HeLa protein fraction.
(11) Evidence is presented that the first step in initiation of SV40 DNA replication involves the specific binding of T antigen to the origin, followed by the local unwinding of the two strands of the template.
(12) Complex formation leads to very little, if any, unwinding of the duplex.
(13) It is suggested that the gene D product may function in replicative form DNA unwinding to expose the template for transcription.
(14) Topotecan (SK&F 104864) is a novel antitumor agent whose mechanism of action is inhibition of the DNA unwinding protein topoisomerase I.
(15) We used an RNA unwinding assay to compare the activities of these factors from the different species.
(16) The extension and unwinding of the DNA helix brought about by the intercalating chromophore of the dye molecules are not requirements for the entrapment process.
(17) Second, mutant T antigens with impaired ATPase function also showed a reduced DNA unwinding activity.
(18) Analysts at UBS said: “After Friday’s ... market plunge, many turned to the authorities for support measures as concerns rose that the rapid unwinding of margin trades was fuelling the sell-off.
(19) It is proposed that the DNA-unwinding activity causes the efficient recombination, DNA repair, and SOS induction (after application of nalidixic acid) in recD mutants.
(20) But within minutes of the five-year-old video of Obama being released by the Daily Caller website on Tuesday night , the "exclusive" began to unwind amid criticism that much of it had been reported at the time and the content was anything but explosive.