(n.) A tree (Antiaris toxicaria) of the Breadfruit family, common in the forests of Java and the neighboring islands. Its secretions are poisonous, and it has been fabulously reported that the atmosphere about it is deleterious. Called also bohun upas.
(n.) A virulent poison used in Java and the adjacent islands for poisoning arrows. One kind, upas antiar, is, derived from upas tree (Antiaris toxicaria). Upas tieute is prepared from a climbing plant (Strychnos Tieute).
Example Sentences:
(1) Binding of uPA to filters was blocked by a synthetic oligopeptide containing the known receptor binding region of native uPA.
(2) The synthesis of uPA as a precursor with reduced enzymatic activity as well as decreased affinity for inhibitors is likely to be a mechanism by which normal epidermis regulates plasminogen activation in vivo.
(3) We identified two human melanoma cell lines, MelJuso and MeWo, expressing uPA or tPA as shown at mRNA, protein, and enzyme activity level.
(4) The Jarman UPA score at electoral ward level is not related to psychiatric morbidity, and should not therefore be used for planning local service provision.
(5) Mutants of the pig kidney cell line, LLC-PK1, affected in cAMP metabolism, were examined for cAMP-dependent protein kinase (cAMP-PK) activity and for cAMP-mediated induction of urokinase-type plasminogen activator (uPA).
(6) Since in addition to fibronectin, that can be degraded by uPA or plasmin, chorioallantoic membrane connective tissue contains collagen, we examined the profile of collagenases secreted by the various cell lines in search for an activity that would coincide with the invasive phenotype.
(7) Rat alveolar epithelial cells produce large quantities of urokinase-type plasminogen activator (uPA) in vitro, and uPA expression is modulated in association with cellular differentiation and exposure to inflammatory mediators.
(8) Immunoreactive uPA was induced equally by IFN and TNF, but TNF generated higher levels of PAI-2.
(9) Thus, cathepsin B can substitute for plasmin in the proteolytic activation of pro-uPA to enzymatically active HMW-uPA.
(10) Plasmin formation, dependent on the urokinase-type plasminogen activator (uPA), is discussed in its biochemical, regulatory and physiological aspects and its involvement in cancer malignancy analysed.
(11) (iv) At high concentrations of sigma factor, only certain adenosine-containing dinucleoside monophosphates (ApU, CpA, UpA, and ApA) stimulate the reaction.
(12) The peptide hormone calcitonin induces the accumulation of urokinase-type plasminogen activator (uPA) mRNA in pig kidney LLC-PK1 cells.
(13) PA activity was also associated with the leading edges of migrating epithelium post-scrape and post-burn and was not inhibited by antibodies to either tPA or uPA but was inhibited by amiloride.
(14) However, the RNase A mutant containing residues 63-74 of angiogenin had greatly diminished catalytic activity against uridylyl-(3'----5')-adenosine (UpA), and slightly increased catalytic activity as an inhibitor of translation in vitro.
(15) Hence receptor-bound uPA will promote plasminogen activation and thus the dissolution of the tumor matrix and the basement membrane which is a prerequisite for invasion and metastasis.
(16) Treatment of A431 squamous carcinoma cells (SqCC) with epidermal growth factor (EGF) has previously been shown to result in an induction of the synthesis and extracellular accumulation of uPA and the plasminogen-dependent proteolysis of extracellular matrix (ECM).
(17) Enzymatic properties of phosphorylated urokinase plasminogen activator (P-uPA) (1) extracted from human carcinomatous cell line Detroit 562 cells were compared with those of non-phosphorylated uPA of urinary origin (nP-uPA).
(18) In all of 10 cases, staining for uPA in the normal colon tissue was confined to scattered fibroblastlike cells in the lamina propria.
(19) It is proposed that uPA:uPA-receptor interaction plays a direct role in physiological and pathological processes that require cell migration.
(20) High molecular weight uPA, either as the single-chain precursor or two-chain activated form, bound to the receptor; however, low molecular weight (33 kD) uPA, tPA, or epidermal growth factor did not compete for binding, demonstrating specificity.
Ups
Definition:
Example Sentences:
(1) When allegations of systemic doping and cover-ups first emerged in the runup to the 2013 Russian world athletics championships, an IOC spokesman insisted: “Anti-doping measures in Russia have improved significantly over the last five years with an effective, efficient and new laboratory and equipment in Moscow.” London Olympics were sabotaged by Russia’s doping, report says Read more We now know that the head of that lauded Moscow lab, Grigory Rodchenko, admitted to intentionally destroying 1,417 samples in December last year shortly before Wada officials visited.
(2) The system of automated diagnosis makes it possible to significantly increase the quality and efficacy of wide-scale prophylactic check-ups of the population.
(3) In many ways, they are leading the agenda.” The sustainable growth in focus is funded by UPS.
(4) During follow-ups ranging from 23.2 to 26.7 months, six of eight patients with colonic inertia failed to improve compared with only one of seven with distal slowing.
(5) For Burroughs, who had been publishing ground-breaking books for 20 years without much appreciable financial return, it was association with fame and the music industry, as well as the possible benefits: a wider readership, film hook-ups and more money.
(6) Regarding psoriasis, emotional factors have a strong correlation with onset and flare-ups.
(7) The possible effect of repeated check-ups and their implications are discussed.
(8) A source with close knowledge of the events said a large box was found by employees carrying out screening checks in the UPS facility.
(9) Follow-ups after 2 years revealed that 90% of the students who responded said the course had had some lasting effect on their lives.
(10) The program helps easy study of the different parameters on the conducting rate of the permeable ion through the channel which otherwise would demand intricate experimental set-ups.
(11) They are not rebellious reckless youth, but 50,000 of the cleverest and most hardworking adults of their generation; the cream of their school science classes, serious-minded grown-ups in their 20s and 30s.
(12) As a consequence it must be ensured that spinal cord injured persons receive yearly check-ups in a urological oriented rehabilitation centre where all modern examination methods, including electronic techniques for the measurement of intravesical pressure and urethral resistance, are available.
(13) One year follow-up evaluation was performed for 14 patients, and two year follow-ups for seven patients.
(14) The Australian government has engaged in one of the most successful mass cover-ups I’ve witnessed in my career of documenting human rights violations,” said Neistat.
(15) A clinical pharmacokinetics service can monitor drug concentrations in biologic fluids, design individualized drug-dosing regimens, and carry out pharmacokinetic diagnostic work-ups to help determine the reasons for a patient's unusual response to drug therapy.
(16) The samples could help inform an international response to the attack, which has sharply upped the stakes in Syria's civil war, drawing demands for recrimination and edging a much-feared regional spillover closer to reality.
(17) All patients were followed for at least 5 years, and 50 patients had 10-year follow-ups.
(18) Next his wife, Jay Z isn't much a dancer, and when the tempo upped, he respectfully exited, letting her lead her Beyhive legions through their hip-shaking glory.
(19) These findings suggest that regular health check-ups with an electrocardiogram would be important to detect asymptomatic myocardial infarction and to increase the opportunity of taking secondary preventive measures.
(20) for boys with the CAHPER tests were: sit-ups .42, broad jump .69, shuttle run .50, arm hang .43, 50-yard dash .60, 300-yard run .65; for girls the r values were about half the values for the boys.