(n.) The crab-eating ichneumon (Herpestes urva), native of India. The fur is black, annulated with white at the tip of each hair, and a white streak extends from the mouth to the shoulder.
Example Sentences:
(1) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(2) The ruv minus uvrA minus double mutant is more sensitive to ultraviolet light than the urvA minus single mutant, whereas the strain with ruv and ion mutations shows the same sensitivity to ultraviolet light as the ruv minus single mutant.
Uva
Definition:
(n.) A small pulpy or juicy fruit containing several seeds and having a thin skin, as a grape.
Example Sentences:
(1) UVA and UVB radiation produced a significant increase in the ratio of type III to type I collagen (more than 100% for UVA-irradiated skin and about 60% for UVB-irradiated skin) accompanied by a significantly increased fibronectin biosynthesis (50% or more in all irradiated groups).
(2) Affected individuals were not clinically photosensitive, but their fibroblasts demonstrated gross cytopathic changes, low survival indices and an increased frequency of DNA single strand breaks following exposure to long-wave ultraviolet radiation (UVA).
(3) The mean cumulative ultraviolet A (UVA) dose in three of the six squamous cell carcinoma patients was three times as high as that in the group of nontumor patients.
(4) Experimental induction of PLME lesions in 22 patients, using a pure, high-intensity UVA light source is reported.
(5) This demonstrates that a UVA tan provides photoprotection against acute UVA exposure.
(6) By analysis of co-variance, the melanin content of melanocytes of black and white subjects was significantly (p less than 0.05) associated with susceptibility to UVA killing; melanocytes with high melanin content had high resistance to UVA cytotoxicity and those with low melanin content had low resistance to UVA cytotoxicity.
(7) The predominantly epidermal tumor response in the high UVA-high UVB group suggests that UVA irradiation increases the number of epithelial tumors when given together with carcinogenic doses of UVB radiation.
(8) These data demonstrate that the psoralens and UVA light have direct biological effects on cell-surface membranes.
(9) Hairless mice were irradiated three times a week for 10 weeks with sunlamps (UVA and UVB) and the skin was examined using immunochemical and biochemical techniques.
(10) We compared the in vivo response of melanocytes to single and multiple exposures of narrow band UVA and UVB irradiation which produced visibly equal increases in pigmentation.
(11) Ventral UVA pre-exposure did not appear to affect dorsal skin irritation as expressed by scratch marks.
(12) Two hours after oral administration of therapeutic doses of the drug enough 8-MOP was taken up in vivo by the circulating peripheral lymphocytes to cause significant inhibition of phytohaemagglutinin induced lymphocyte proliferation when the cells were exposed in vitro to UVA irradiation.
(13) The purpose of this study was to examine the dose response and time course relationships between PUVA (psoralen + UVA) depletion of skin glutathione (GSH) and the induction of inflammation.
(14) Inflation of the cuff to greater than systolic pressure completely inhibited immediate and delayed pigment responses (IPD, DT) to UVA doses greater than 10 times the normal pigmentation threshold dose.
(15) The skin of the animals given methoxsalen and UVA showed signs of acute and chronic phototoxicity.
(16) Monoclonal antibodies specific for DNA damaged by 8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) light were used to study adduct formation in human keratinocytes and mouse and rat skin in vivo.
(17) In contrast, a large dose of UVA (320-400 nm) radiation did not suppress CHS but, rather, enhanced this immune response.
(18) Since 1975 oral 8-methoxypsoralen administered in association with ultraviolet-A radiation (UVA), (PUVA) has been widely used to treat psoriasis and other cutaneous diseases.
(19) The psoralen analogs 8-methoxypsoralen (8-MOP) and 4,5',8-trimethylpsoralen (TMP), in combination with ultraviolet light (UVA, 320-400 nm), are potent modulators of epidermal cell growth and differentiation and are commonly used in photochemotherapy of psoriasis and vitiligo.
(20) The carcinogenic effect of 3 commercially available ultraviolet A (UVA) tanning sources was studied in lightly pigmented hairless mice.