(v. t.) The act of employing anything, or of applying it to one's service; the state of being so employed or applied; application; employment; conversion to some purpose; as, the use of a pen in writing; his machines are in general use.
(v. t.) Occasion or need to employ; necessity; as, to have no further use for a book.
(v. t.) Yielding of service; advantage derived; capability of being used; usefulness; utility.
(v. t.) Continued or repeated practice; customary employment; usage; custom; manner; habit.
(v. t.) Common occurrence; ordinary experience.
(v. t.) The special form of ritual adopted for use in any diocese; as, the Sarum, or Canterbury, use; the Hereford use; the York use; the Roman use; etc.
(v. t.) The premium paid for the possession and employment of borrowed money; interest; usury.
(v. t.) The benefit or profit of lands and tenements. Use imports a trust and confidence reposed in a man for the holding of lands. He to whose use or benefit the trust is intended shall enjoy the profits. An estate is granted and limited to A for the use of B.
(v. t.) A stab of iron welded to the side of a forging, as a shaft, near the end, and afterward drawn down, by hammering, so as to lengthen the forging.
(v. t.) To make use of; to convert to one's service; to avail one's self of; to employ; to put a purpose; as, to use a plow; to use a chair; to use time; to use flour for food; to use water for irrigation.
(v. t.) To behave toward; to act with regard to; to treat; as, to use a beast cruelly.
(v. t.) To practice customarily; to make a practice of; as, to use diligence in business.
(v. t.) To accustom; to habituate; to render familiar by practice; to inure; -- employed chiefly in the passive participle; as, men used to cold and hunger; soldiers used to hardships and danger.
(v. i.) To be wont or accustomed; to be in the habit or practice; as, he used to ride daily; -- now disused in the present tense, perhaps because of the similarity in sound, between "use to," and "used to."
(v. i.) To be accustomed to go; to frequent; to inhabit; to dwell; -- sometimes followed by of.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Therefore, these findings may extend the use of platelets as neuronal models.
(4) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(5) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(6) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(7) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(8) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(9) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(10) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(11) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(12) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(13) Questionnaires were used and the respondent self-designation method measured leadership.
(14) At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Use of the improved operative technique contributed to reduction in number of complications.
(17) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(18) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(19) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(20) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
Worthless
Definition:
(a.) Destitute of worth; having no value, virtue, excellence, dignity, or the like; undeserving; valueless; useless; vile; mean; as, a worthless garment; a worthless ship; a worthless man or woman; a worthless magistrate.
Example Sentences:
(1) KR: She was truly in a conundrum because without the app, she felt too worthless to try and fix it by installing an update.
(2) The lack of Ab2 anti-Ab1 anti-HLA makes worthless the utilization of such preparations for neutralization of Ab1 present in highly sensitized dialysis patients or suppression of their production in transplanted patients in contrast with the previous reports suggesting this possibility.
(3) Former Labour science minister Lord Sainsbury said any assurances would be "frankly meaningless" given Pfizer's history of asset-stripping.Allan Black, of the GMB union which represents workers at AstraZenea's Macclesfield factory, said of Pfizer's latest pledges: "Similar undertakings were given by US multinationals before which have proved to be worthless."
(4) The biggest loser could be the state-owned oil company Rosneft, which bought Yukos assets in auctions when the latter's stock was almost worthless.
(5) Nobody is sure what dangerous chemical imbalance this would create but the Fiver is convinced we'd all be dust come October or November, the earth scorched, with only three survivors roaming o'er the barren landscape: Govan's answer to King Lear, ranting into a hole in the ground; a mute, wild-eyed pundit, staring without blinking into a hole in the ground; and a tall, irritable figure standing in front of the pair of them, screaming in the style popularised by Klaus Kinski, demanding they take a look at his goddamn trouser arrangement, which he has balanced here on the platform of his hand for easy perusal, or to hell with them, for they are no better than pigs, worthless, spineless pigs.
(6) Where we revere and anthropomorphise such brutal predators as sharks, tigers and bears, we view these tiny ectoparasites as worthless, an evolutionary accident with no redeeming or adorable characteristics.
(7) In addition to the climate risk, the Bank of England and others argue that fossil fuel assets may pose a “huge risk” to pension funds and other investors as they could be rendered worthless by action to slash carbon emissions.
(8) We have to acknowledge that it's extremely hard to build a regular city from scratch.” Furthermore, some experts say that certified green buildings and pedestrian-friendly roads are a worthless patch for China’s environmental woes, not a solution.
(9) His comments came as voucher experts said consumers have probably lost at least £100m in now worthless HMV vouchers.
(10) Chris Leslie, Labour's shadow financial secretary to the Treasury, said: "Nobody doubts that Stephen Hester has done some important things at RBS, but what this award shows is David Cameron's promises about reining in excessive bonuses at state-owned banks or using shareholder power have proved to be utterly worthless.
(11) The drop in ventricular septal temperature was so small that topical hypothermia, by itself, may be worthless.
(12) The responses to the upper half field stimulation showed greatest variation making the VEP recording worthless in detecting altitudinal visual field defects.
(13) The future of Game Group is hanging by a thread after it filed for administration and admitted the business was worthless, jeopardising 6,000 jobs in the UK.
(14) But it is all merely worthless and meaningless froth while the city council permits a gateway to hell to do brisk business just a few streets away.
(15) If we look at who has what in Syria, you will see that Isis is only controlling the desert, and it is worthless.
(16) "He had no job, he didn't go on holiday … he felt worthless … Thank you, Theresa May , from the bottom of my heart – I always knew you had the strength and courage to do the right thing."
(17) But companies spent $670bn (£436bn) in 2013 alone searching for more fossil fuels, investments that could be worthless if action on global warming slashes allowed emissions.
(18) It's all there: sexual and social confusion, vulnerability and violence, alienation and loneliness, the oscillation between feeling abject and worthless and wanting to take over the world, the fantasies of power and revenge.
(19) In May, the then prime minister, Naoto Kan, ordered the killing of livestock by lethal injection after radiation made them commercially worthless.
(20) I have been charged very little but I'm concerned that many people holidaying in France will book their car through Firefly, only to discover that their booking is worthless because they cannot drive across the border.