(n.) A small pulpy or juicy fruit containing several seeds and having a thin skin, as a grape.
Example Sentences:
(1) UVA and UVB radiation produced a significant increase in the ratio of type III to type I collagen (more than 100% for UVA-irradiated skin and about 60% for UVB-irradiated skin) accompanied by a significantly increased fibronectin biosynthesis (50% or more in all irradiated groups).
(2) Affected individuals were not clinically photosensitive, but their fibroblasts demonstrated gross cytopathic changes, low survival indices and an increased frequency of DNA single strand breaks following exposure to long-wave ultraviolet radiation (UVA).
(3) The mean cumulative ultraviolet A (UVA) dose in three of the six squamous cell carcinoma patients was three times as high as that in the group of nontumor patients.
(4) Experimental induction of PLME lesions in 22 patients, using a pure, high-intensity UVA light source is reported.
(5) This demonstrates that a UVA tan provides photoprotection against acute UVA exposure.
(6) By analysis of co-variance, the melanin content of melanocytes of black and white subjects was significantly (p less than 0.05) associated with susceptibility to UVA killing; melanocytes with high melanin content had high resistance to UVA cytotoxicity and those with low melanin content had low resistance to UVA cytotoxicity.
(7) The predominantly epidermal tumor response in the high UVA-high UVB group suggests that UVA irradiation increases the number of epithelial tumors when given together with carcinogenic doses of UVB radiation.
(8) These data demonstrate that the psoralens and UVA light have direct biological effects on cell-surface membranes.
(9) Hairless mice were irradiated three times a week for 10 weeks with sunlamps (UVA and UVB) and the skin was examined using immunochemical and biochemical techniques.
(10) We compared the in vivo response of melanocytes to single and multiple exposures of narrow band UVA and UVB irradiation which produced visibly equal increases in pigmentation.
(11) Ventral UVA pre-exposure did not appear to affect dorsal skin irritation as expressed by scratch marks.
(12) Two hours after oral administration of therapeutic doses of the drug enough 8-MOP was taken up in vivo by the circulating peripheral lymphocytes to cause significant inhibition of phytohaemagglutinin induced lymphocyte proliferation when the cells were exposed in vitro to UVA irradiation.
(13) The purpose of this study was to examine the dose response and time course relationships between PUVA (psoralen + UVA) depletion of skin glutathione (GSH) and the induction of inflammation.
(14) Inflation of the cuff to greater than systolic pressure completely inhibited immediate and delayed pigment responses (IPD, DT) to UVA doses greater than 10 times the normal pigmentation threshold dose.
(15) The skin of the animals given methoxsalen and UVA showed signs of acute and chronic phototoxicity.
(16) Monoclonal antibodies specific for DNA damaged by 8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) light were used to study adduct formation in human keratinocytes and mouse and rat skin in vivo.
(17) In contrast, a large dose of UVA (320-400 nm) radiation did not suppress CHS but, rather, enhanced this immune response.
(18) Since 1975 oral 8-methoxypsoralen administered in association with ultraviolet-A radiation (UVA), (PUVA) has been widely used to treat psoriasis and other cutaneous diseases.
(19) The psoralen analogs 8-methoxypsoralen (8-MOP) and 4,5',8-trimethylpsoralen (TMP), in combination with ultraviolet light (UVA, 320-400 nm), are potent modulators of epidermal cell growth and differentiation and are commonly used in photochemotherapy of psoriasis and vitiligo.
(20) The carcinogenic effect of 3 commercially available ultraviolet A (UVA) tanning sources was studied in lightly pigmented hairless mice.
Uvea
Definition:
(n.) The posterior pigmented layer of the iris; -- sometimes applied to the whole iris together with the choroid coat.
Example Sentences:
(1) Beta-Glucuronidase activity was higher in the anterior uvea but lower in the corneoscleral tissues.
(2) Phthisical eyes of 2 patients revealed clinically unsuspected, partially necrotic and partially vital malignant melanomas of the uvea and extensive intraocular ossification.
(3) Anterior segment involvement was slight or nonexistent, and damage to the retina and uvea was of a focal rather than of a diffuse nature.
(4) 125I-Albumin permeation was increased in the retina, choroid, and anterior uvea of rats fed 50% galactose for 3 weeks, 3 months, and 8 months versus controls, but was unchanged in the brain.
(5) There is controversy regarding the origin of the pigment-containing epithelioid cells in the uvea of eyes with sympathetic ophthalmia.
(6) In conscious animals 5 pmol kg-1 CGRP caused enhanced leakage from the blood vessels of the ciliary processes in those pre-treated with biperiden in order to abolish the cholinergic vasoconstrictor tone in the anterior uvea.
(7) Detectable mast cells in the anterior uvea of S-Ag-immunized Lewis rats decreased to 60% of control at 6 days postimmunization, recovered to 80% at 10 days, and dropped again to 16% at 13 days, with disease onset around 14 days.
(8) Histopathologic examination disclosed a diffuse malignant melanoma of the uvea, mixed cell type, with multiple cysts of the ciliary epithelium.
(9) Perchlorate (10(-4) M) and iodide (10(-4) or 10(-3) M) had no inhibitory effect while 10(-4) M p-aminohippuric acid had a significant inhibitory effect on the kidney cortex at a concentration of 10(-4) M and on the anterior uvea at 10(-3) M. 4.
(10) In STZ-D rats, 131I-BSA tissue clearance increased significantly (2- to 4-fold) in the anterior uvea, choroid-sclera, retina, sciatic nerve, aorta, new granulation tissue, diaphragm, and kidney but was unchanged in skin, forelimb muscle, and heart.
(11) The authors' results are consistent with the finding in animal experiments that blood flow to the retina, optic nerve, and uvea increases for a short time after oculopression (Jay et al., Acta Ophthalmol.
(12) Melanocytomas are pigmented tumors of the uvea and optic nerve head composed of plump polyhedral melanocytes which have been regarded as nevus cells.
(13) The dedifferentiated tumour in the enucleated eyes spread extensively within the anterior chamber and anterior uvea.
(14) The management of posterior penetrating ocular trauma includes thorough preoperative evaluation and exploration and careful debridement with excision or repositioning of the uvea.
(15) ET-1 also caused vasodilation in the anterior uvea.
(16) However, Ia was expressed in the anterior uvea epithelial cells in all eyes with LPS induced uveitis.
(17) The strongly vascularized anterior uvea is used as a carrier and a connecting link to the immune system.
(18) Thus, the anterior uvea in mammals may be one of the tissues exhibiting a cholinergic vasoconstriction phenomenon, found more commonly in lower vertebrates.
(19) Uvea-retina, synovial membrane, and articular cartilage antigen preparations inhibited the migration of leukocytes from patients with rheumatoid arthritis.
(20) No differences could be asserted in autoantibody frequencies according to disease location within the uvea.