(n.) A more or less elongated mark raised by a stroke; also, a similar mark made by any cause; a weal; a wale.
(n.) Specifically (Med.), a flat, burning or itching eminence on the skin, such as is produced by a mosquito bite, or in urticaria.
(n.) A mine.
Example Sentences:
(1) Three patients reacted with a wheal size greater than or equal to a histamine control at a dilution of 1:1,000 and 3 patients at 1:100.
(2) The validation of the VSC technique with venous occlusion plethysmography (VOP) showed that the increase of time of disappearance of the wheals is well correlated with the increase of capillary permeability demonstrated by VOP.
(3) Cimetidine, an H2-receptor antagonist slightly reduced the effect of clonidine on the wheal and flare reaction.
(4) Numerous mast cells were degranulated in late wheals, as shown by electron microscopy.
(5) The wheal and erythema reaction caused by intracutaneous application of 5 mug histamine can be inhibited by applying fenoterol in doses from 100--400 mug in form of a metered aerosol on the skin 5 min before the injection of histamine.
(6) Treatment with astemizole, as measured at the end point of each patient's treatment and compared to placebo, resulted in significant improvement of pruritus, erythema, number of wheals, frequency of urticarial attacks, and control of urticaria (p less than or equal to 0.03).
(7) The surface areas of the wheal and flare responses were measured by planimetry.
(8) Substance P produces dose-related wheal and flare reactions in human skin.
(9) Clinically, they are characterised by an immediate wheal and flare or a delayed papular to eczematous process.
(10) The flare response to SP and histamine was suppressed by capsaicin pretreatment whereas the wheal was enlarged.
(11) Histamine caused dose-related increases in blood flow and in areas of wheal and erythema in human skin.
(12) The patient developed an immediate type of skin reaction with erythema and whealing following monochromatic irradiation at 400 nm, but did not have any abnormal immediate skin reaction after exposure to natural sunlight.
(13) The allergen-triggered wheal and flare reaction in ovalbumin sensitized guinea pigs was potentiated by MK 422 and the late phase reaction of the inflammatory response was especially augmented.
(14) Except at high doses the local vasodilatation induced by CGRP was not associated with a wheal and flare as seen with histamine, substance P, and VIP.
(15) Two other patients with sunlight-induced solar urticaria, who had an erythema-and-wheal reaction during and after exposure to sunlight, had no suppressive wave bands in either the UV or visible-light range.
(16) There were also 3 highly allergic children, with immediate hypersensitivity reactions to other food, who, despite having never been exposed to egg, developed large skin prick test wheals to egg white.
(17) It is concluded that the wheal need not be associated with the Provocation-Neutralisation technique, and that a neuropsychological basis for the Provocation-Neutralisation response should be explored.
(18) Pressure wheals were characterized by a mild mononuclear perivascular infiltrate and by patchy dermal infiltrates of eosinophils.
(19) Sections from the wheals of recent onset 24 hours old or less taken from 11 patients with urticaria were examined by electron microscopy.
(20) Five minutes after an id injection of PHA (bactophytohaemoagglutinin M, Difco, 1 mg), mix monilieae, mix tricophyton and PPD Berna, she showed an extensive wheal and flare reaction in the PHA injection area, eyelid oedema and respiratory distress.
Wheat
Definition:
(n.) A cereal grass (Triticum vulgare) and its grain, which furnishes a white flour for bread, and, next to rice, is the grain most largely used by the human race.
Example Sentences:
(1) RNA transcribed in vitro from the early region of bacteriophage T3 or T7 was translated by cytoplasmic ribosomes which synthesized protein in cell-free systems prepared from mammalian cells and wheat germ.
(2) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(3) They included lectins such as wheat germ agglutinin (WGA), concanavalin A and phytohemagglutinin, and a chemical cross-linker, glutaraldehyde, in addition to anti-IL-2R monoclonal antibodies, HIEI and H-47.
(4) Two lectins, wheat germ agglutinin (WGA) and peanut agglutinin (PNA), were used to compare domains within the interphotoreceptor matrices (IPM) of the cat and monkey, two species where the morphological relationship between the retinal pigment epithelium (RPE) and photoreceptors is distinctly different.
(5) The lambs of the second group were given 1200-1500 g of concentrate pellets and 300 g chopped wheat straw, and those of the third group were given 800 and 1050 g each of concentrate pellets, and 540 g and 720 g of pellets of whole maize plant containing 40 per cent.
(6) The absorption of zinc from meals based on 60 g of rye, barley, oatmeal, triticale or whole wheat was studied by use of extrinsic labelling with 65Zn and measurement of the whole-body retention of the radionuclide.
(7) Comparison of the native and derivatized wheat germ CaMs with native bovine testis CaM indicates that the concentrations of these proteins required for half-maximal stimulation of either erythrocyte membrane Ca2+-ATPase activity or cardiac sarcoplasmic reticulum phosphorylation are very similar.
(8) Recoveries of these 3 herbicides added to soil, wheat, and barley samples at 0.05, 0.1, 0.5, and 1.0 ppm levels were between 65 and 93%.
(9) The 5'-terminal methylated cap (m7G(5')ppp(5')Gm) in reovirus messenger RNA comprises part of the ribosomes binding site, since attachment of 40 S wheat germ ribosomal subunits to reovirus small (s), medium (m), and large (l) RNA classes conferred almost complete protection of the cap against RNase digestion.
(10) Injection of the tracer substance wheat germ agglutinin-horseradish peroxidase (WGA-HRP) directly into the basilar pontine nuclei using a ventral surgical approach resulted in the labeling of somata in many areas both rostral and caudal to the basilar pons.
(11) The organization of the afferent and efferent connections of the sagittal Zones A and B of the cerebellar cortex of the rat have been studied using wheat-germ agglutinin conjugated to horseradish peroxidase as a tracer.
(12) He can't eat wheat – he has to have a special diet.
(13) Previous experiments had demonstrated that the receptors for the lectins soybean agglutinin (SBA), wheat germ agglutinin, concanavalin A and Lens culinaris agglutinin all were relatively uniformly distributed on both myoblasts and myotubes, and that SBA receptors were capable of rapid redistribution on myotubes but not myoblasts at 4 degrees C (Sawyer & Akeson, 1983).
(14) The purification entails cell lysis and solubilization of gpL115 with the detergent Nonidet P-40, sequential affinity chromatography on lentil lectin-Sepharose, wheat germ lectin-Sepharose, and, after treatment with sialidase, on peanut lectin-Sepharose.
(15) It is now recognized that dwarfism in males is frequent around the Mediterranean, where wheat is the staple of life and has been grown for 4,000 years on the same soil, thereby resulting in the depletion of zinc.
(16) The characteristics of the surface of guinea pig megakaryocytes were investigated with wheat germ agglutinin (WGA).
(17) On the other hand, wheat bran, pectin, guar gum, and degraded carageenan all stimulate large bowel cell proliferation, the greatest growth response tending to occur in the cecum or proximal colon.
(18) A lectin which binds to both sialic acid and N-acetylglucosamine sugar residues, wheat germ agglutinin-ferritin (WGA-fe), was used.
(19) Two similar, 41- and 67-kDa G-proteins were identified in the wheat germ-purified insulin receptor preparations obtained from human placenta.
(20) Succinylated wheat germ agglutinin bound more to crypt than to villus enterocytes.