(1) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
(2) The effects of phenoxyacetic acid herbicides were investigated on the induction of chromosome aberrations in human peripheral lymphocyte cultures in vitro and in lymphocytes of exposed workers in vivo.
(3) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(4) Maximal aberration yields were observed for 2,4-diaminotoluene, 2,6-diaminotoluene and cytosine beta-D-arabinofuranoside from 17 to 21 h, eugenol from 15 to 21 h, cadmium sulfate from 15 to 24 h and 2-aminobiphenyl, from 17 to 24 h. For adriamycin at 1 microM, the % aberrant cells remained elevated throughout the period from 9 to 29 h, while small increases at 0.1 microM ADR were found only at 13 and at 25 h. For most chemicals the maximal aberration yield occurred at a different time for each concentration tested.
(5) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(6) Detailed studies of the between-cell aberration distributions give evidence that positive selection against cells with high aberration frequencies has also occurred in these experiments.
(7) Chromosome aberrations were scored in BHK21 C13 Syrian hamster fibroblasts, exposed to 60Co gamma-rays, 250 kV X-rays, 15 MeV neutrons or neutrons of mean energy 2.1 MeV produced from the 9Be(d,n)10B reaction.
(8) Immense amounts of data about cancer-associated chromosome aberrations have been collected during the last 10 years, and the systematic evaluation of these data has disclosed a number of correlations between chromosome change and neoplastic disease.
(9) ECGs taken routinely over a period of years help differntiate ventricular from supraventricular tachycardias with aberrant conduction.
(10) In three patients treated with photrine cells with aberrative karyotypes ranged within 14-37.5%.
(11) 50 cells at metaphase per animal were scored for chromosomal aberrations.
(12) Thus, in human lymphocytes the frequencies of chromatid aberrations induced by most clastogenic agents were strongly enhanced when caffeine was given during the G2 phase, but little affected by post-treatments with caffeine during the S phase.
(13) Systematic treatment of aberrant subclavian arteries should perhaps be considered when it can be performed during thoracic surgery.
(14) At that time the factor IX users also had milder immune aberrations than the hemophilia A group.
(15) The predominant specific aberrations in gliomas were an over-representation of chromosome 7 (13 cases) and an under-representation of chromosome 10 (16 cases).
(16) It was shown that six pesticides induced a statistically significant increase in the number of chromosomal aberrations: Bi 58 EC, Metasystox (I) forte, Sadofos 30, Nogos 50 EC, Foschlor 25 and Thiodan 35.
(17) Cystic dystrophy of aberrant pancreatic tissue without chronic pancreatitis is a rare disease described by Potet and Duclert in 1970.
(18) Methyl sinapate also increased the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.
(19) In the exposed group structural chromosome aberrations were found in 2%, while in the control group in 0.9% of analysed metaphases.
(20) These findings indicate structural abnormalities in the secretory apparatus of neuroendocrine cells in dysplastic bronchi and correlate with experimental observations of aberrant hormonal production associated with bronchial dysplasia.
Deviation
Definition:
(n.) The act of deviating; a wandering from the way; variation from the common way, from an established rule, etc.; departure, as from the right course or the path of duty.
(n.) The state or result of having deviated; a transgression; an act of sin; an error; an offense.
(n.) The voluntary and unnecessary departure of a ship from, or delay in, the regular and usual course of the specific voyage insured, thus releasing the underwriters from their responsibility.
Example Sentences:
(1) Only in 17 of the 97 examinees all the examined parameters were found normal, in the rest deviations from the normal echographic picture were revealed.
(2) Deviations in two planes simultaneously cause less error than deviation in one plane.
(3) The percent pause time, the standard deviation of the voice fundamental frequency distribution, the standard deviation of the rate of change of the voice fundamental frequency and the average speed of voice change were found to correlate to the clinical state of the patient.
(4) This study examined the frequency of occurrence of velar deviations in spontaneous single-word utterances over a 6-month period for 40 children who ranged in age from 1:11 (years:months) to 3:1 at the first observation.
(5) The average lung density, its standard deviation which was used as a measure of the density homogeneity throughout the lung, and the densities of smaller lung regions were measured before and up to 76 weeks after irradiation in rat lungs.
(6) The zeta potential as a function of ionic strength deviates significantly from the predictions of the double-layer theory in the 10(-3)-5.10(-2) M range.
(7) The most striking differences were observed on the factors: Psychopathic deviation, Mania, Schizophrenia greater than controls and social introversion lower than controls.
(8) A maximum deviation of approximately 10% was found.
(9) Deviations from isotropic motion observed for the non-aromatic moieties are discussed.
(10) The most substantial deviations between actual and theoretical osmolarity values occurred with the calcium chloride, sodium bicarbonate, potassium chloride and dextrose solutions.
(11) Deviations from Michealis-Menten kinetics in the pig-heart citrate synthase (citrate-oxaloacetate-lyase(pro-3S-CH2-COO-leads to acetyl-CoA), EC 4.1.3.7) system have been characterized and analyzed in view of the kinetic theory described in the preceding paper.
(12) Finally, the in vivo loss of cholesterol feedback control was found to occur in at least two minimal deviation hepatomas and in one highly malignant adenocarcinoma of hepatic origin.
(13) For data sampled at a high rate (approximately 200 Hz) pupil velocity deviations from zero can simply be used, giving a satisfactory inaccuracy of about 5 ms. For data sampled at a low rate (less than 50 Hz), e.g.
(14) Breakpoints and other deviations from a linear PPR over the whole ICP range are studied by the analysis of the transfer function.
(15) The three counties sampled showed surprisingly little deviation in the percentages of inventories suggesting alcohol production and in the preferences for specific types of drinks.
(16) The fraction of ligands that initially escaped into the solvent decreased when the temperature was lowered, and the Arrhenius plots for the rebinding rate coefficients were found to deviate significantly from linearity.
(17) The jaw deviated to the right when he opened his mouth fully.
(18) With the Cardiovascular Measurement System (CMS), 1 standard deviation for repeat measurements of minimum diameter increased from 0.087 mm (same frame to 0.240 mm (films one to 6 months apart).
(19) The standard deviations were greatest when the AI was near 50% and least when the AI was near 0% or 100%.
(20) Variability of basal blood flow in terms of standard deviations and in terms of coefficients of variation computed from duplicate determinations were significantly higher than for the other parameters and significantly more elevated in the forearm than in the calf.