(a.) Deviating from the ordinary or natural type; exceptional; abnormal.
Example Sentences:
(1) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
(2) The effects of phenoxyacetic acid herbicides were investigated on the induction of chromosome aberrations in human peripheral lymphocyte cultures in vitro and in lymphocytes of exposed workers in vivo.
(3) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(4) Maximal aberration yields were observed for 2,4-diaminotoluene, 2,6-diaminotoluene and cytosine beta-D-arabinofuranoside from 17 to 21 h, eugenol from 15 to 21 h, cadmium sulfate from 15 to 24 h and 2-aminobiphenyl, from 17 to 24 h. For adriamycin at 1 microM, the % aberrant cells remained elevated throughout the period from 9 to 29 h, while small increases at 0.1 microM ADR were found only at 13 and at 25 h. For most chemicals the maximal aberration yield occurred at a different time for each concentration tested.
(5) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(6) Detailed studies of the between-cell aberration distributions give evidence that positive selection against cells with high aberration frequencies has also occurred in these experiments.
(7) Chromosome aberrations were scored in BHK21 C13 Syrian hamster fibroblasts, exposed to 60Co gamma-rays, 250 kV X-rays, 15 MeV neutrons or neutrons of mean energy 2.1 MeV produced from the 9Be(d,n)10B reaction.
(8) Immense amounts of data about cancer-associated chromosome aberrations have been collected during the last 10 years, and the systematic evaluation of these data has disclosed a number of correlations between chromosome change and neoplastic disease.
(9) ECGs taken routinely over a period of years help differntiate ventricular from supraventricular tachycardias with aberrant conduction.
(10) In three patients treated with photrine cells with aberrative karyotypes ranged within 14-37.5%.
(11) 50 cells at metaphase per animal were scored for chromosomal aberrations.
(12) Thus, in human lymphocytes the frequencies of chromatid aberrations induced by most clastogenic agents were strongly enhanced when caffeine was given during the G2 phase, but little affected by post-treatments with caffeine during the S phase.
(13) Systematic treatment of aberrant subclavian arteries should perhaps be considered when it can be performed during thoracic surgery.
(14) At that time the factor IX users also had milder immune aberrations than the hemophilia A group.
(15) The predominant specific aberrations in gliomas were an over-representation of chromosome 7 (13 cases) and an under-representation of chromosome 10 (16 cases).
(16) It was shown that six pesticides induced a statistically significant increase in the number of chromosomal aberrations: Bi 58 EC, Metasystox (I) forte, Sadofos 30, Nogos 50 EC, Foschlor 25 and Thiodan 35.
(17) Cystic dystrophy of aberrant pancreatic tissue without chronic pancreatitis is a rare disease described by Potet and Duclert in 1970.
(18) Methyl sinapate also increased the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.
(19) In the exposed group structural chromosome aberrations were found in 2%, while in the control group in 0.9% of analysed metaphases.
(20) These findings indicate structural abnormalities in the secretory apparatus of neuroendocrine cells in dysplastic bronchi and correlate with experimental observations of aberrant hormonal production associated with bronchial dysplasia.
Irregular
Definition:
(a.) Not regular; not conforming to a law, method, or usage recognized as the general rule; not according to common form; not conformable to nature, to the rules of moral rectitude, or to established principles; not normal; unnatural; immethodical; unsymmetrical; erratic; no straight; not uniform; as, an irregular line; an irregular figure; an irregular verse; an irregular physician; an irregular proceeding; irregular motion; irregular conduct, etc. Cf. Regular.
(n.) One who is not regular; especially, a soldier not in regular service.
Example Sentences:
(1) Aggregation was more frequent in low-osmolal media: mainly rouleaux were formed in ioxaglate but irregular aggregates in non-ionic media.
(2) They were more irregularly curved and consisted of various substances.
(3) The results of the measurements permitted the identification of five main cytologic types, with regard to nuclear size, nuclear area dispersion and irregularity of nuclear profiles.
(4) A detailed stereochemical analysis of known protein structures has been made which shows that: (1) irregular regions of proteins consist of a limited number of standard structures formed by three, four of more residues; (2) an amino acid residue of a protein can adopt one of the six sterically allowed conformations designated here as alpha, alpha L, beta, gamma, delta, and epsilon.
(5) Endoscopy showed an irregular erosion of 4 by 2 cm, from which biopsies were taken.
(6) Aside from typical nuclear spheroids, irregularly shaped nuclei were frequently seen, associated with increased nuclear folds, transitional stages between nuclear folds and nuclear spheroids were also present.
(7) Although the level of ventilation is maintained constant during eating and drinking, the pattern of breathing becomes increasingly irregular.
(8) Numerous slender sarcotubules, originating from the A-band side terminal cisternae, extend obliquely or longitudinally and form oval or irregular shaped networks of various sizes in front of the A-band, then become continuous with the tiny mesh (fenestrated collar) in front of the H-band.
(9) What happened in the past was that if smugglers are sure that European boats are patrolling very close to the Libyan coast, then traffickers use this opportunity to advertise, and say to potential irregular migrants: ‘You will be sure to reach the European coast.
(10) In contrast, mean diameter of normal epicardial coronary artery tended to decrease and that of irregular epicardial coronary artery decreased significantly after intracoronary injection of acetylcholine.
(11) These findings are in agreement with the concept that irregular lesions represent ruptured atherosclerotic plaques and demonstrate that they usually originate from mildly occlusive smooth plaques.
(12) After 21 months, there appears to be no correlation between the amount of material adhering to the IUD and method complications (irregular and excessive bleeding) or method failure (pregnancy).
(13) The patient described in this report has the classic findings of Bardet-Biedl syndrome in conjunction with tibia vara and irregular physes of the lower extremities.
(14) After cessation her previously regular menstrual periods became very irregular and complete amenorrhea had lasted 4 months.
(15) Histochemical and electron-microscopic observations on a 30-month-old child with Hurler syndrome showed marked irregularities in chondrocyte orientation within the growth plate, along with disruption of the normal columnar architecture.
(16) The endocrine pattern and ovarian characteristics of 110 healthy adolescents with menstrual irregularities were investigated during the early follicular and premenstrual phases and were compared to those of 14 adolescents with regular menstrual cycles and 20 adults.
(17) Hypertrophy of the satellite cells with increase in the perineuronal intercellular spaces, often associated with irregular, scalloped nuclear and cell outlines, suggested that neuron shrinkage had occurred.
(18) Light microscopic examination of irregularly thickened white and black portions of abnormal scales demonstrated two distinctive populations of pigment-containing cells.
(19) In the second hypertrophied form [Type II], the endoplasmic reticulum is very prominent and occurs as a series of grossly dilated sacs of irregular shape.
(20) Disruption of the rhythmic activity of the inspiratory neurons and its replacement by a continuous and irregular discharge may lead to sustained contraction of inspiratory muscles and cessation of respiration.