(n.) The act of wandering; deviation, especially from truth or moral rectitude, from the natural state, or from a type.
(n.) A partial alienation of reason.
(n.) A small periodical change of position in the stars and other heavenly bodies, due to the combined effect of the motion of light and the motion of the observer; called annual aberration, when the observer's motion is that of the earth in its orbit, and daily or diurnal aberration, when of the earth on its axis; amounting when greatest, in the former case, to 20.4'', and in the latter, to 0.3''. Planetary aberration is that due to the motion of light and the motion of the planet relative to the earth.
(n.) The convergence to different foci, by a lens or mirror, of rays of light emanating from one and the same point, or the deviation of such rays from a single focus; called spherical aberration, when due to the spherical form of the lens or mirror, such form giving different foci for central and marginal rays; and chromatic aberration, when due to different refrangibilities of the colored rays of the spectrum, those of each color having a distinct focus.
(n.) The passage of blood or other fluid into parts not appropriate for it.
(n.) The producing of an unintended effect by the glancing of an instrument, as when a shot intended for A glances and strikes B.
Example Sentences:
(1) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
(2) The effects of phenoxyacetic acid herbicides were investigated on the induction of chromosome aberrations in human peripheral lymphocyte cultures in vitro and in lymphocytes of exposed workers in vivo.
(3) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(4) Maximal aberration yields were observed for 2,4-diaminotoluene, 2,6-diaminotoluene and cytosine beta-D-arabinofuranoside from 17 to 21 h, eugenol from 15 to 21 h, cadmium sulfate from 15 to 24 h and 2-aminobiphenyl, from 17 to 24 h. For adriamycin at 1 microM, the % aberrant cells remained elevated throughout the period from 9 to 29 h, while small increases at 0.1 microM ADR were found only at 13 and at 25 h. For most chemicals the maximal aberration yield occurred at a different time for each concentration tested.
(5) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(6) Detailed studies of the between-cell aberration distributions give evidence that positive selection against cells with high aberration frequencies has also occurred in these experiments.
(7) Chromosome aberrations were scored in BHK21 C13 Syrian hamster fibroblasts, exposed to 60Co gamma-rays, 250 kV X-rays, 15 MeV neutrons or neutrons of mean energy 2.1 MeV produced from the 9Be(d,n)10B reaction.
(8) Immense amounts of data about cancer-associated chromosome aberrations have been collected during the last 10 years, and the systematic evaluation of these data has disclosed a number of correlations between chromosome change and neoplastic disease.
(9) ECGs taken routinely over a period of years help differntiate ventricular from supraventricular tachycardias with aberrant conduction.
(10) In three patients treated with photrine cells with aberrative karyotypes ranged within 14-37.5%.
(11) 50 cells at metaphase per animal were scored for chromosomal aberrations.
(12) Thus, in human lymphocytes the frequencies of chromatid aberrations induced by most clastogenic agents were strongly enhanced when caffeine was given during the G2 phase, but little affected by post-treatments with caffeine during the S phase.
(13) Systematic treatment of aberrant subclavian arteries should perhaps be considered when it can be performed during thoracic surgery.
(14) At that time the factor IX users also had milder immune aberrations than the hemophilia A group.
(15) The predominant specific aberrations in gliomas were an over-representation of chromosome 7 (13 cases) and an under-representation of chromosome 10 (16 cases).
(16) It was shown that six pesticides induced a statistically significant increase in the number of chromosomal aberrations: Bi 58 EC, Metasystox (I) forte, Sadofos 30, Nogos 50 EC, Foschlor 25 and Thiodan 35.
(17) Cystic dystrophy of aberrant pancreatic tissue without chronic pancreatitis is a rare disease described by Potet and Duclert in 1970.
(18) Methyl sinapate also increased the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.
(19) In the exposed group structural chromosome aberrations were found in 2%, while in the control group in 0.9% of analysed metaphases.
(20) These findings indicate structural abnormalities in the secretory apparatus of neuroendocrine cells in dysplastic bronchi and correlate with experimental observations of aberrant hormonal production associated with bronchial dysplasia.
Observer
Definition:
(n.) One who observes, or pays attention to, anything; especially, one engaged in, or trained to habits of, close and exact observation; as, an astronomical observer.
(n.) One who keeps any law, custom, regulation, rite, etc.; one who conforms to anything in practice.
(n.) One who fulfills or performs; as, an observer of his promises.
(n.) A sycophantic follower.
Example Sentences:
(1) The patterns observed were: clusters of granules related to the cell membrane; positive staining localized to portions of the cell membrane, and, less commonly, the whole cell circumference.
(2) However, this deficit was observed only when the sample-place preceded but not when it followed the interpolated visits (second experiment).
(3) In conclusion, in S-rats a glucose-stimulated insulin release is accompanied by an increase in IBF, but this is not observed in P-rats.
(4) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
(5) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(6) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(7) Stimulation is also observed with mixtures of APC expressing DPw3 and APC expressing A1, and likewise, DPw3+ APC become stimulatory when preincubated with supernatants from A1-positive cells.
(8) For this reason, these observations should not be disregarded.
(9) No differences between the two substances were observed with respect to side effects and general tolerability.
(10) The testing of other models and their failure to describe the kinetic observations are discussed.
(11) The extrusion of granules into the intercellular space via exocytosis is frequently observed.
(12) The time of observation varied between 2 and 17 years.
(13) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(14) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(15) No reaction product was observed in the lamellar areas.
(16) Cyanoacrylate and PDS coatings were not detectable after 6 weeks while PHBA and PLLA coatings were still observed after 48 weeks.
(17) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(18) This new observation offers good possibilities to study the metabolism of tryptophan at the cellular level.
(19) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(20) The fluctuations in [Ca2+]i measured with fura-2 were synchronized among the population of cells observed and were sensitive to extracellular Ca2+ concentration ([Ca2+]o).