(a.) Not conformed to rule or system; deviating from the type; anomalous; irregular.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(3) Clonal abnormalities involving chromosomes 3 and 21 were noted in two patients.
(4) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(5) Among a family of 8 children, 4 presented typical clinical and biological abnormalities related to mannosidosis.
(6) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(7) The secondary leukemia that occurred in these patients could be distinguished from the secondary leukemia that occurs after treatment with alkylating agents by the following: a shorter latency period; a predominance of monocytic or myelomonocytic features; and frequent cytogenetic abnormalities involving 11q23.
(8) Immediate postexercise two-dimensional echocardiography demonstrated exercise-induced changes in 8 (47%) patients (2 with normal and 6 with abnormal results from rest studies).
(9) The psychiatric experts classified 11 of the perpetrators as "normal," 3 as abnormal, and 2 as psychotic.
(10) Erythrocyte membrane choline transport is abnormally high in chronic renal failure.
(11) Although the longest period required for resolving weakness was three days, the MRI, the CT and the electroencephalogram revealed no significant abnormality.
(12) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(13) Muscle wasting in MYD may be explained by these abnormalities as well.
(14) Associated renal and other abnormalities were common.
(15) Once the normal variations are mastered, appreciation of retinal, choroidal, optic nerve, and vitreal abnormalities is possible.
(16) Eight other children (20%) had normal or borderline elevation of CPK-MB fraction and EKG abnormalities combined with abnormal echocardiograms or radionuclide angiograms, and were considered to have sustained cardiac concussion.
(17) Several investigators have attempted to correlate chromosomal abnormalities with Cornelia de Lange Syndrome (CLS), but none of them have been conclusive.
(18) It is possible that the IgE that linked abnormally with the propofol had specific binding sites for the phenyl nucleus and the isopropyl groups, which are present in propofol and many other drugs.
(19) Of 185 with readable histology, 14.6% were clinically and histologically abnormal; 19.5% were clinically abnormal but histologically normal; and 15.7% were clinically normal and histologically abnormal.
(20) Mice also had a decreased ability to develop delayed-type hypersensitivity reactions while being given cadmium; this abnormality also returned toward normal after withdrawal of cadmium.
Conform
Definition:
(a.) Of the same form; similar in import; conformable.
(v. t.) To shape in accordance with; to make like; to bring into harmony or agreement with; -- usually with to or unto.
(v. i.) To be in accord or harmony; to comply; to be obedient; to submit; -- with to or with.
(v. i.) To comply with the usages of the Established Church; to be a conformist.
Example Sentences:
(1) The interaction of the antibody with both the bacterial and the tissue derived polysialic acids suggests that the conformational epitope critical for the interaction is formed by both classes of compounds.
(2) It has been conformed that catalase from bovine liver eliminates only the pro R hydrogen atom from ethanol.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(5) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
(6) Recently, we have designed a series of simplified artificial signal sequences and have shown that a proline residue in the signal sequence plays an important role in the secretion of human lysozyme in yeast, presumably by altering the conformation of the signal sequence [Yamamoto, Y., Taniyama, Y., & Kikuchi, M. (1989) Biochemistry 28, 2728-2732].
(7) The molecule may already in its native form have an extended conformation containing either free sulfhydryl groups or small S-S loops not affecting mobility in SDS-PAGE.
(8) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
(9) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
(10) However, it does not and we therefore propose the presence of an unusual DNA conformation in these regions.
(11) We propose that, for a GC base pair in B conformation, there are two amino proton exchangeable states--a cytosine amino proton exchangeable state and a guanine amino proton exchangeable state; both require the disruption of only the corresponding interbase H bond.
(12) In air-saturated solutions of DNA, yields of 8-hydroxypurines were not influenced greatly by DNA conformation.
(13) A detailed stereochemical analysis of known protein structures has been made which shows that: (1) irregular regions of proteins consist of a limited number of standard structures formed by three, four of more residues; (2) an amino acid residue of a protein can adopt one of the six sterically allowed conformations designated here as alpha, alpha L, beta, gamma, delta, and epsilon.
(14) The substructural units, 5-14 linear and 5-14 cyclic, have been used as models for MCH-- H-Asp1-Thr-Met-Arg-Cys-Met-Val-Gly-Arg HO-Val17-Glu-Trp-Cys-Pro-Arg-Tyr-Val in 1H-nmr conformational studies.
(15) The conformations of each peptide in various solvents were determined by CD and ir spectroscopy in order to relate immunological to structural properties.
(16) All data did, however, conform to normal distribution expectations.
(17) The conformations of cysteamine, thiazolidine, and thiazolidine-4-carboxylic acid were determined in aqueous solutions using NMR spectroscopy.
(18) This structural change opens the heme pocket and modifies the general conformation of the EF segment, thus explaining the increase in oxygen affinity and the achievement of a three-dimensional structure favoring asparagine deamidation.
(19) It is likely that the molecule undergoes a conformational change when it is bound to the receptor.
(20) The phenylalanine-dependent conformation and the leucine-dependent conformation differ considerably.