(n.) One who, or that which, accumulates, collects, or amasses.
(n.) An apparatus by means of which energy or power can be stored, such as the cylinder or tank for storing water for hydraulic elevators, the secondary or storage battery used for accumulating the energy of electrical charges, etc.
(n.) A system of elastic springs for relieving the strain upon a rope, as in deep-sea dredging.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(5) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(6) The data support the conclusion that accumulation of lipid II is responsible in some way for the hypersensitivity of delta rfbA mutants to SDS.
(7) In addition, the guanosine 3',5'-cyclic monophosphate accumulation response was less impressive in glomeruli than the guanylate cyclase response in IMCD tissue.
(8) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(9) At 24 or 48 hours after ischemia, 63Ni, 99TcO4, and 22Na were preferentially concentrated in the damaged striatum and hippocampus, whereas 65Zn, 59Fe, 32PO4, and 147Pm did not accumulate in irreversibly injured tissue.
(10) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(11) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(12) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
(13) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.
(14) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(15) The data shows a dissociation between ferritin synthesis, cellular accumulation and secretion for which the mechanisms have still to be elucidated.
(16) The rate of accumulation was highest late in infection and only the slower migrating form incorporates significant amounts of glucosamine.
(17) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(18) Accumulating evidence indicates that for most tumors, the switch to the angiogenic phenotype depends upon the outcome of a balance between angiogenic stimulators and angiogenic inhibitors, both of which may be produced by tumor cells and perhaps by certain host cells.
(19) The aim of our experiments was to investigate firstly whether during an acute inflammatory process platelets accumulate in the inflamed area and secondly whether the inflammation has an effect on the properties of the platelets.
(20) The accumulated evidence would strongly favor an affirmative answer.
Stake
Definition:
(v. t.) To fasten, support, or defend with stakes; as, to stake vines or plants.
(v. t.) A piece of wood, usually long and slender, pointed at one end so as to be easily driven into the ground as a support or stay; as, a stake to support vines, fences, hedges, etc.
(v. t.) A stick inserted upright in a lop, eye, or mortise, at the side or end of a cart, a flat car, or the like, to prevent goods from falling off.
(v. t.) The piece of timber to which a martyr was affixed to be burned; hence, martyrdom by fire.
(v. t.) A small anvil usually furnished with a tang to enter a hole in a bench top, -- used by tinsmiths, blacksmiths, etc., for light work, punching upon, etc.
(v. t.) That which is laid down as a wager; that which is staked or hazarded; a pledge.
(v. t.) To mark the limits of by stakes; -- with out; as, to stake out land; to stake out a new road.
(v. t.) To put at hazard upon the issue of competition, or upon a future contingency; to wager; to pledge.
(v. t.) To pierce or wound with a stake.
Example Sentences:
(1) It is not clear whether Sports Direct, which has a history of taking strategic stakes in related companies including Debenhams and JD Sports, will now make a bid.
(2) Even so, the release of the first-half figures could help clear the way for the chancellor, George Osborne, to start selling off the taxpayer’s 79% stake in the bank, a legacy of the institution’s 2008 bailout.
(3) The Press Association tots up a total of £26bn in asset sales last year – including the state’s Eurostar stake, 30% of the Royal Mail and a slice of Lloyds.
(4) Shares in the bank have fallen more than 30% since Britain voted to leave the EU and the share closed on Monday at 167p, well below the 502p average price at which taxpayers bought their stake in the bank.
(5) Cobra collapsed into administration in 2009 after which Lord Bilimoria was criticised for using a “pre-pack” deal to buy back a stake in the firm.
(6) Republicans remain wary of a contentious debate on the divisive issue, which could anger their core voters and undercut potential electoral gains in the November elections when control of Congress will be at stake.
(7) But Mr Bolloré, with a 29% stake in Aegis, vowed to keep calling shareholder meetings until he gets his way.
(8) Xenophon’s letter says if State Grid is also allowed to own a huge stake in Ausgrid it raises serious questions about market dominance.
(9) Rawlins bought a stake in Stoke City in 2000, where he'd been a season ticket-holder from the age of five, after selling off his IT consultancy company and joined the board.
(10) They also point to her involvement, between 1999 and 2005, with Computer Associates-Jinchen, a joint venture between an American tech company and a Chinese firm in which China’s ministry of public security reportedly held a 20% stake.
(11) That stake in eight Indonesian coal mines represents 1GT of future carbon dioxide emissions, more than Germany’s annual output.
(12) Buffett’s fortune was briefly boosted by another $5.7bn purely on his personal stake in Kraft Heinz, whose shares rose 10%, while Unilever shares rose 13.4% to a record high.
(13) Despite its 25% stake, BP said it would be wrong to assume that it would obtain a quarter of the expected $100bn worth of revenues.
(14) Most of the money, says WDM, was used to buy shares in Bumi , the troubled London-listed firm co-founded by financier Nat Rothschild that owns large stakes in some of the biggest mining projects in East Kalimantan.
(15) They will not be able to vote out the non-execs because Ashley has that vast stake, but there are occasions when principles are important and this September's AGM will be one of them.
(16) Shell has pulled out of renewables: it retains a small stake in biofuels development, but the company's offshore wind business is no more.
(17) Rupert Murdoch has a battle on his hands to win over leading shareholders in BSkyB, who scent the opportunity for a high-stakes game of brinkmanship and are pushing for a premium price of well over £10bn for full control of the pay-television company.
(18) The future of our children, grandchildren and beyond is at stake.
(19) To maintain its 30% stake the Co-op would need to stump up another £120m, increasing its already high debt levels.
(20) Two years later, the privately held Lovefilm acquired Amazon's UK and German movie rental business, with the online retail giant taking a stake in the business as part of the deal.