What's the difference between aching and desire?

Aching


Definition:

  • (p. pr. & vb. n.) of Ache
  • (a.) That aches; continuously painful. See Ache.

Example Sentences:

  • (1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
  • (2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
  • (3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
  • (4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
  • (5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
  • (6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
  • (7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
  • (8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
  • (9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
  • (10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
  • (11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
  • (12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
  • (13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
  • (14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
  • (15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
  • (16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
  • (17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
  • (18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
  • (19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
  • (20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.

Desire


Definition:

  • (v. t.) To long for; to wish for earnestly; to covet.
  • (v. t.) To express a wish for; to entreat; to request.
  • (v. t.) To require; to demand; to claim.
  • (v. t.) To miss; to regret.
  • (v. t.) The natural longing that is excited by the enjoyment or the thought of any good, and impels to action or effort its continuance or possession; an eager wish to obtain or enjoy.
  • (v. t.) An expressed wish; a request; petition.
  • (v. t.) Anything which is desired; an object of longing.
  • (v. t.) Excessive or morbid longing; lust; appetite.
  • (v. t.) Grief; regret.

Example Sentences:

  • (1) I'm not sure Tolstoy ever worked out how he actually felt about love and desire, or how he should feel about it.
  • (2) Further improvement of results will be possible by early operation, a desirable objective.
  • (3) This has been accomplished by insertion of a desired gene into a pre-existing immortal cell or by immortalizing primary cells.
  • (4) The light intensity profile for any desired cell can be examined in "real time", even during acceleration of the rotor.
  • (5) Still, even as unknowable as this decision may be for him, as any decision is, really, he is far more qualified to understand his desires and goals that would inform that decision than anyone else is.
  • (6) It’s not just a matter of will or gumption or desire on my part.
  • (7) "The pattern of consumption is that among ebook readers there is a desire to pre-order, or get it quickly, so ebook sales are particularly high in the first few weeks," he said.
  • (8) Attention is drawn to the desirability of differentiating between supra- and sub-gingival calculus in the CPITN scoring system and to the excessive treatment requirements that arise from classifying everyone with calculus as requiring prophylaxis and scaling.
  • (9) Alternatively, the data presented herein strongly suggest that diets containing conventional quantities of fat, in which saturated fat is replaced by unsaturated fat and dietary cholesterol reduced, would result in the desired reductions to total and low-density lipoprotein cholesterol concentrations without the adverse effects of increased postprandial glucose and insulin concentrations, increased fasting and postprandial total and very-low-density lipoprotein triglyceride concentrations, and decreased fasting high-density lipoprotein cholesterol concentrations.
  • (10) Combining drugs may only occasionally be advisable to supplement a desired effect or to attenuate an unwanted one.
  • (11) Five hundred sixty grandmultiparous women were interviewed as to their contraceptive awareness, desirability and use in the three major hospitals in Benin City, Nigeria, between October 1, 1980 and September, 1981.
  • (12) It will not be so low as to put off candidates from outside the corporation but will be substantially less than Thompson's £671,000 annual remuneration – in line with Patten's desire to clamp down on BBC executive pay, which he said had become a "toxic issue".
  • (13) The concept of increasing bone mass and decreasing expanded soft-tissue mass has application within the judgment of the surgeon coupled with the patient's desires.
  • (14) This new derivative could represent a desirable complementation to rhbFGF for the development of more stable pharmaceutical formulations in wound healing applications.
  • (15) These concepts of facial harmony and surgical alterations have been difficult to teach in a residency program, especially regarding preoperative evaluation and a clear idea of the desired surgical results.
  • (16) Subsequent efforts focused on achieving high levels of insecticidal activity while minimizing costs of synthesis and retaining desirable levels of selective toxicity.
  • (17) The reasons are often financial, but can also be a desire for a change of pace or new experiences.
  • (18) Noninvasive procedures (such as Holter monitoring or recording of late potentials) are desirable for screening purposes, whereas it would be acceptable to use more aggressive invasive techniques in certain subsets of patients.
  • (19) KAP studies have demonstrated differences in the family size desires of men and women and in the determinants of attitudes toward birth control.
  • (20) An accurate description of the coronary anatomy is desired before anatomic correction of d-transposition of the great arteries.

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