(1) Astrocyte conditioned medium (ACM) enhanced the survival of neurons and the proliferation of astrocytes in embryonic cortical cultures grown in serum-free defined medium.
(2) Race 4 transconjugants containing avrB0 induced a dark brown necrotic HR within 24 h on the soybean cultivars Harosoy and Norchief, whereas race 4 transconjugants containing avrC induced a light brown necrotic HR within 48 h on the soybean cultivars Acme, Peking, Norchief, and Flambeau.
(3) Posterior fossa decompression with obex plugging (the Gardner operation) was the procedure of choice for SM-ACM and for idiopathic holocord syringomyelia.
(4) A variety of protected peptides up to tetradecapeptides have been chromatographed at pressures of 50 to 150 psi and obtained in analytically pure from within 2 to 4 h. With such commonly used protecting groups as N-benzyloxycarbonyl (Z), N-2-(p-biphenylyl)-2-propyloxycarbonyl (Bpoc), N-t-butyloxycarbonyl (Boc), O- and S-t-butyl (But), and S-acetamidomethyl (Acm), compounds were sufficiently soluble in chloroform, alcohols, acetic acid, or mixtures of these solvents for column loading.
(5) Material was fixed in buffered-formalin solution and embedded in metacrylate or Durcupan ACM.
(6) In a phase I-II study, 19 patients with acute lymphoid leukemia (ALL) and 8 patients with non-Hodgkin lymphoma (NHL) were given ACM alone according to the regimen designated treatment 1 described above.
(7) The lack of significant abnormalities in post-ictal polysomnograms corresponds to a functional integrity of the brainstem structures involved in the global organization of sleep and may represent a useful laboratory feature in the diagnosis of ACM.
(8) Proliferation of CFU-acm can be controlled by humoral factors and this allows us to conclude that they are not identical to CFUs and probably belong to the compartment of early hemopoietic cells of the granulocyte series.
(9) Sequential studies of the self-limited HgCl2 GN showed that glomerular PCA, proteinuria and glomerular fibrin deposits peaked concomitantly at the acme of the disease, suggesting that immunologically mediated glomerular damage had triggered the extrinsic coagulation pathway.
(10) The ACMS said the mining industry ads ignored the impacts of industrialisation, which it called “the fastest growing threat to the reef”.
(11) Conversely, the exposure of cells to the anthracycline compounds at 0 degree C resulted in almost complete disappearance of cell kill effects except with ACM; ACM retained substantial cell kill effects even at the given low temperature.
(12) With the MM cells, hyperthermia potentiated the cytotoxic effects of doxorubicin (ADM), daunorubicin, mitoxantrone (DHAD), and quelamycin but did not enhance that of aclacinomycin (ACM).
(13) These data lead us to conclude that ACM-DOX association partly reverses the DOX resistance at clinically achievable concentrations.
(14) The significance of these observations was discussed in terms of possible interactions at the level of ACM and CAF biotransformation and the potential for interactions of CAF with other xenobiotics.
(15) That triumphal speech was his apex, the acme, the zenith of his career.
(16) The therapeutic value of these compounds for established ACME remains uncertain.
(17) The structural basis of this bleeding disorder has been further assessed by studying the interaction of the following Val(12)-substituted human fibrinogen-like peptides with bovine thrombin in aqueous solution by use of two-dimensional NMR spectroscopy (including TRNOE): Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala- Glu-Val(12)-Gly-Gly-Val-Arg(16)-Gly(17)-Pro-Arg-Val-NH2 (F16), Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16) (tF16), Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16)-Gly(17)-Pro-Arg-Val-Cys(Acm)-NH2 (F17), and Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly- Val-Arg(16) (tF17).
(18) A sensitive enzyme immunoassay method (EIA) for an anticancer drug, aclacinomycin A (ACM), has been developed.
(19) A comparison of the ACM aa sequence with the aa sequences of other proteins in the NBRF data base reveals that ACM has strong similarity to the N-O-diacetylmuramidase secreted by the fungus Chalaropsis.
(20) None of the 8 patients suffering from ovarial cancer benefitted from ACM therapy.
Mercurial
Definition:
(a.) Having the qualities fabled to belong to the god Mercury; swift; active; sprightly; fickle; volatile; changeable; as, a mercurial youth; a mercurial temperament.
(a.) Having the form or image of Mercury; -- applied to ancient guideposts.
(a.) Of or pertaining to Mercury as the god of trade; hence, money-making; crafty.
(a.) Of or pertaining to, or containing, mercury; as, mercurial preparations, barometer. See Mercury, 2.
(a.) Caused by the use of mercury; as, mercurial sore mouth.
(n.) A person having mercurial qualities.
(n.) A preparation containing mercury.
Example Sentences:
(1) There is a considerably larger variability of the mercury levels in urine than in blood.
(2) Mercury compounds and EDTA were found to be potent inhibitors of proteinase yscJ activity.
(3) The effects of postnatal methyl mercury exposure on the ontogeny of renal and hepatic responsiveness to trophic stimuli were examined.
(4) The fact that it is still used is regrettable yet unavoidable at present, but the average quantity is three times less than the mercury released into the atmosphere by burning the extra coal need to power equivalent incandescent bulbs.
(5) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(6) Concern about the safety of the patient and dental personnel does exist, however, due to the possibilities of mercury poisoning.
(7) In order to determine the specific action of cadmium on bone metabolism, the effect of cadmium on alkaline phosphatase activity, a marker enzyme of osteoblasts, was compared with that of other divalent heavy metal ions, i.e., zinc, manganese, lead, copper, nickel and mercury (10 microM each), using cloned osteoblast-like cells, MC3T3-E1.
(8) Inorganic mercury as HgSO4 or HgCl2, at dietary levels up to 200 p.p.m.
(9) An analysis of the clinical markers indicated no clear relationship between elevated urinary mercury concentrations and kidney dysfunction.
(10) In vivo the administration of captopril prevented the toxic effects of mercury poisoning on membrane permeability, oxidative phosphorylation and Ca++ homeostasis.
(11) Histological changes were similar in inorganic and methyl mercury treated fish except the higher intensity observed in the latter treatment.
(12) Unlike other eukaryotic enzymes, the plant enzyme showed no activation with organic mercurials and was inhibited by urea and KCl.
(13) Postoperative APR improved to 86.3 millimeters of mercury and ABI to 0.63 (p less than 0.05).
(14) Attempts to induce mercury resistance in the aerobic isolates were successful, but no induction was seen in the anaerobes.
(15) High concentrations of mercury, cadmium, and lead have also been observed in urban soils.
(16) In the presence of peripheral vasodilatation, adequate blood flow can be expected after such bypass grafts at blood pressures as low as 80 millimeters of mercury and hypotension per se does not produce vascular steal.
(17) A transistor radio activated by a mercury switch was used to reinforce head posture in two retarded children with severe cerebral palsy.
(18) This species, therefore, seems to be about twice as sensitive to the neurotoxic properties of methyl mercury salts as the laboratory rat.
(19) Under this condition, MeHg- and Hg(++)-induced increases in fluorescence were associated with depolarization of psi p. A second approach was used to assess changes in psi p. In synaptosomes, the magnitude of the increase in fluorescence resulting from depolarization of psi p with a stimulus of constant intensity is a function of the resting psi p. The fluorescence response to depolarization of synaptosomes previously exposed to either MeHg or Hg++ (1-20 microM each) was reduced in a concentration-dependent manner relative to mercury-free controls.
(20) Of the tubular cell ultrastructures, the lysosome was the most sensitive to mercury, and there was a close relation between the excretion of urinary mercury and the mercury detoxication mechanism of the kidney.