(n.) Doing; trouble; difficulty; troublesome business; fuss; bustle; as, to make a great ado about trifles.
Example Sentences:
(1) This inhibition was correlated with the enhanced Ado toxicity, suggesting inhibition of methylation as a possible causal factor for the great increase in Ado sensitivity.
(2) S-Adenosyl-L-methionine (Ado-met) administration to rats significantly improved liver necrosis induced by thioacetamide (TAA) as evidenced by reduction of TAA-elevated catalytic activity of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALAT).
(3) Apparent Michaelis (Km) constants for the two cosubstrates for the reaction, 6-MP and S-adenosyl-L-methionine (Ado-Met), in mouse kidney were 7.0 X 10(-4) M and 2.4 X 10(-6) M respectively.
(4) Since ADO is a metabolic substrate and a nonselective receptor agonist, while CHA is A1-selective and a poor substrate for cellular uptake, neither A2 activation nor cellular uptake altered expression of the A1 effect of exogenous ADO.
(5) Both 20 microM nitrobenzylthioinosine (NBMPR), an inhibitor of the purine nucleoside carrier, and 0.1 mM alpha,beta-methylene adenosine diphosphate (AOPCP), an inhibitor of 5'-nucleotidase activity, attenuate DNP-stimulated ADO release (NBMPR by 62% and ADOCP by 76%).
(6) The effect of adenosine (ADO) on the recovery of cellular adenine nucleotides (AN) was evaluated in the cultured cells deprived of oxygen and substrates (ischemia) and in nonischemic cells (control).
(7) The brain dialysis technique was used to (a) deliver drugs locally to brain tissue, (b) estimate cerebral ISF ADO levels, and (c) measure local CBF (hydrogen clearance).
(8) The present experiments were designed to examine the effects of Ado and adenosine analogues on net chloride (JCl) and bicarbonate (JHCO3) absorption by the isolated, perfused MTAL of the rat.
(9) In other tissues, such as adipose and skeletal muscle, much attention has focused on the role of ADO as a metabolic regulator of the actions of insulin.
(10) Adenosine (ADO) in low micromolar levels and hypoxanthine (HYP) in millimolar levels have been shown to inhibit maturation of cumulus-enclosed oocytes.
(11) Mitogenic stimulation of B cell DNA synthesis was antagonized by 2Cl Ado while adenosine produced both stimulations and inhibitions.
(12) These results suggest that the beta-adrenergic stimulation the interstitial level of ADO in the heart increases to levels that are sufficient to manifest its antiadrenergic effects.
(13) In an experiment with tRNAPhe which is a substrate for a single, namely m5C methylase, the type of inhibition of this methylase by S-Cyd-Hcy was revealed; it was found to be non-competitive with respect to S-Ado-Met, and the S-Cyd-Hcy concentration reducing the methylation by 50 percent was 1.2-10(-4) M.
(14) He also appeared in a number of Branagh's films including Much Ado About Nothing (1993) and as Polonius in Hamlet (1996).
(15) These results provide indirect evidence that in enterocytes methylmalonyl-CoA mutase, the coenzyme of which is Ado-Cbl, is located in the mitochondrial fraction and that methionine synthetase, the coenzyme of which is Me-Cbl, is located in the sap fraction.
(16) Now Michael, what was the word I just said?” I told her the word was “Monday” and, with no more ado, she returned to her desk and clattered something out on her computer.
(17) Nevertheless, the antiviral action of F-C-Ado appears to be targeted at AdoHcy hydrolase.
(18) Low (nM) amounts of the Ado agonists inhibited cAMP formation in both cell types.
(19) This was confirmed by the comparison of the rates of hydrolysis of m7Guo5'PPP5'Ado by the enzyme in the presence of various nucleotides.
(20) He owed his late-flourishing film career to Branagh, appearing in a string of his movies: as Bardolph in Henry V (1989), Leonato in Much Ado About Nothing (1993), the old blind man in Mary Shelley's Frankenstein (1994), a cantankerous old thespian in A Midwinter's Tale (1995), Polonius in Hamlet (1996) and Sir Nathaniel in the musical Love's Labour's Lost (2000).
Stir
Definition:
(v. t.) To change the place of in any manner; to move.
(v. t.) To disturb the relative position of the particles of, as of a liquid, by passing something through it; to agitate; as, to stir a pudding with a spoon.
(v. t.) To bring into debate; to agitate; to moot.
(v. t.) To incite to action; to arouse; to instigate; to prompt; to excite.
(v. i.) To move; to change one's position.
(v. i.) To be in motion; to be active or bustling; to exert or busy one's self.
(v. i.) To become the object of notice; to be on foot.
(v. i.) To rise, or be up, in the morning.
(n.) The act or result of stirring; agitation; tumult; bustle; noise or various movements.
(n.) Public disturbance or commotion; tumultuous disorder; seditious uproar.
(n.) Agitation of thoughts; conflicting passions.
Example Sentences:
(1) I'm married to an Irish woman, and she remembers in the atmosphere stirred up in the 1970s people spitting on her.
(2) Koons provoked a bigger stir with the news that he would be showing with gallery owner David Zwirner next year in an apparent defection from Zwirner's arch-rival Larry Gagosian, the world's most powerful art dealer.
(3) The apparent Km for K+-ATP was 2.1 mM when the incubation mixture was vigorously stirred, and the effect of stirring indicated that the kinetics of K+-ATP hydrolysis are limited by external diffusion.
(4) The last time Republic of Ireland played here in Dublin they produced a performance and result to stir the senses.
(5) This modification facilitated a wider range of application of the Kedem-Katchalsky equations to systems in which the solutions were stirred or unstirred.
(6) Sheryl Sandberg gave the commencement speech at UC Berkeley last weekend, during the course of which she said many stirring things about the future awaiting the class of 2016.
(7) In a sign of deep unease among senior Tories at some of the party’s tactics, Forsyth accused the prime minister of having “shattered” the pro-UK alliance in Scotland and stirring up English nationalism after the Scottish independence referendum last year.
(8) Additionally, in 12 of 15 cases examined by Short-TI-IR (STIR) image, the trabecular structures and fluid collections in the subcutaneous tissue were shown more definitely in high signal intensity than by T2-weighted image.
(9) Add the onion, cook for three minutes, stirring, until softened, then add the wine, sage, lemon peel, lemon juice and 150ml water.
(10) We examined the effect of ethylene glycol (EG) concentration, in water, on O2 sensitivity, stirring effect, in vitro drift, in vitro response time, behaviour on the skin of newborn infants and in vivo response time.
(11) Stirring of the sample induced a significant decrease of neutrophils (P less than 0.001) but no changes of red blood cell (RBC) and platelet count.
(12) There was no potentiation when A119 alone was pre-stirred or left standing for several days in the presence of divalent cations prior to use.
(13) I drive past buildings that I know, or assume, to house bedsits, their stucco peeling like eczema, their window frames rattling like old bones, and I cannot help myself from picturing the scene within: a dubious pot on an equally dubious single ring, the female in charge of it half-heartedly stirring its contents at the same time as she files her nails, reads an old Vogue, or chats to some distant parent on the telephone.
(14) 3) After stirring for 1 and 5 minutes, there was a negative correlation (Spearmann's rank correlation coefficient test) between the pH values of the sport drinks and the amounts of Ca2+ released into them.
(15) Simmer for 2 minutes then stir in the orange zest, orange blossom water and vanilla extract.
(16) And after stirring for 10 and 20 minutes, there was a negative correlation between the Ca concentrations of the sport drinks and the amounts of Ca2+ released into them.
(17) Having stirred the viewer's emotional responsiveness, the art work provides a reliable "container" for the objectification of latent emotions.
(18) The inversion recovery sequence with short inversion time (STIR) will suppress signal from fat tissue and this is of particular value in differentiating dermoid from hemorrhagic cyst.
(19) At different intensities of medium stirring the lysins synthesizing activity was directly related to the activity of tricarboxylic acid cycle dehydrogenases.
(20) The experimental result of the quantitative determination of magnolol in Cortex Magnoliae Officinalis and its processed samples by HPLC has shown that the stir-fried sample has the highest content of magnolol among all sample and so does the ginger-fried sample among all ginger-processed samples.