(v. t.) To bring forward; to move towards the van or front; to make to go on.
(v. t.) To raise; to elevate.
(v. t.) To raise to a higher rank; to promote.
(v. t.) To accelerate the growth or progress; to further; to forward; to help on; to aid; to heighten; as, to advance the ripening of fruit; to advance one's interests.
(v. t.) To bring to view or notice; to offer or propose; to show; as, to advance an argument.
(v. t.) To make earlier, as an event or date; to hasten.
(v. t.) To furnish, as money or other value, before it becomes due, or in aid of an enterprise; to supply beforehand; as, a merchant advances money on a contract or on goods consigned to him.
(v. t.) To raise to a higher point; to enhance; to raise in rate; as, to advance the price of goods.
(v. t.) To extol; to laud.
(v. i.) To move or go forward; to proceed; as, he advanced to greet me.
(v. i.) To increase or make progress in any respect; as, to advance in knowledge, in stature, in years, in price.
(v. i.) To rise in rank, office, or consequence; to be preferred or promoted.
(v.) The act of advancing or moving forward or upward; progress.
(v.) Improvement or progression, physically, mentally, morally, or socially; as, an advance in health, knowledge, or religion; an advance in rank or office.
(v.) An addition to the price; rise in price or value; as, an advance on the prime cost of goods.
(v.) The first step towards the attainment of a result; approach made to gain favor, to form an acquaintance, to adjust a difference, etc.; an overture; a tender; an offer; -- usually in the plural.
(v.) A furnishing of something before an equivalent is received (as money or goods), towards a capital or stock, or on loan; payment beforehand; the money or goods thus furnished; money or value supplied beforehand.
(a.) Before in place, or beforehand in time; -- used for advanced; as, an advance guard, or that before the main guard or body of an army; advance payment, or that made before it is due; advance proofs, advance sheets, pages of a forthcoming volume, received in advance of the time of publication.
Example Sentences:
(1) This selective review emphasizes advances in neurochemistry which provide a context for current and future research on neurological and psychiatric disorders encountered in clinical practice.
(2) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(3) These results suggest that the pelvic floor is affected by progressive denervation but descent during straining tends to decrease with advancing age.
(4) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
(5) When TSLP was pretreated with TF5 in vitro, the most restorative effects on the decreased MLR were found in hyperplastic stage and the effects were becoming less with the advance of tumor developments.
(6) Finally the advanced automation of the equipment allowed weekly the evaluation of catecholamines and the whole range of their known metabolites in 36 urine samples.
(7) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(8) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(9) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(10) Under a revised deal most people are now being vetted on time, but charges for the service have had to rise from £12 and free vetting for volunteers, to £28 for a standard disclosure and £33 for an advanced disclosure.
(11) Histological and electron-microscopic study of the lungs of 15 patients who had been treated with bleomycin for advanced squamous cell carcinoma demonstrated marked histological changes in nine.
(12) With better understanding of metabolic and compositional requirements, great advances have been made in the area of total parenteral nutrition.
(13) Meanwhile Ed Miliband, the Labour leader, waiting anxiously for news of the scale of the Labour advance in his first nationwide electoral test, will urge the electorate not to be duped by the promise of a coalition mark 2, predicting sham concessions by the Conservatives .
(14) 16 tube (usually a Baker tube) was inserted by gastrostomy and advanced distally into the colon.
(15) Of his number, 266 patients were in the advance stage of their disease while another 42 still had localized cancers.
(16) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(17) Serial antepartum platelet alloantibody quantitation by an enzyme-linked immunoabsorbent assay revealed rising antibody titers during advancing gestation.
(18) Most of the progressive cases were alcoholic, and some showed progression to advanced pancreatitis within 4 years.
(19) Expansion of the cell sheet following attachment, and the fusion of epiblasts advancing toward each other, does not require the presence of mineralocorticoid.
(20) One hundred and sixteen patients with advanced and metastatic adenocarcinoma of the pancreas were randomized to treatment with combined Streptozotocin and 5-fluorouracil or combined Streptozotocin and cyclophosphamide.
Elevate
Definition:
(a.) Elevated; raised aloft.
(v. t.) To bring from a lower place to a higher; to lift up; to raise; as, to elevate a weight, a flagstaff, etc.
(v. t.) To raise to a higher station; to promote; as, to elevate to an office, or to a high social position.
(v. t.) To raise from a depressed state; to animate; to cheer; as, to elevate the spirits.
(v. t.) To exalt; to ennoble; to dignify; as, to elevate the mind or character.
(v. t.) To raise to a higher pitch, or to a greater degree of loudness; -- said of sounds; as, to elevate the voice.
(v. t.) To intoxicate in a slight degree; to render tipsy.
(v. t.) To lessen; to detract from; to disparage.
Example Sentences:
(1) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(2) Intestinal dilatation seemed in all cases a response to elevated CO2 only.
(3) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(4) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(5) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(6) The increase in red blood cell mass was associated with an elevation in erythropoietic stimulatory activity in serum, pleural fluid, and tumor-cyst fluid as determined by the exhypoxic polycythemic mouse assay.
(7) Maximal aberration yields were observed for 2,4-diaminotoluene, 2,6-diaminotoluene and cytosine beta-D-arabinofuranoside from 17 to 21 h, eugenol from 15 to 21 h, cadmium sulfate from 15 to 24 h and 2-aminobiphenyl, from 17 to 24 h. For adriamycin at 1 microM, the % aberrant cells remained elevated throughout the period from 9 to 29 h, while small increases at 0.1 microM ADR were found only at 13 and at 25 h. For most chemicals the maximal aberration yield occurred at a different time for each concentration tested.
(8) Hepatic enzyme elevations were more dramatic after blunt trauma, reflecting greater hepatocellular disruption.
(9) The erythrocyte sedimentation rate is almost always markedly elevated.
(10) Total cholesterol levels are elevated, particularly in hypopituitary women.
(11) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(12) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
(13) If tracer is introduced into the carotid artery after osmotic treatment, brain uptake is increased by a net factor of 50 (a factor of 70 due to elevation of PA, multiplied by 7 due to infusion by the carotid route) as compared to uptake by normal, untreated brain with infusion into a peripheral vein.
(14) Beta-galactosidase, beta-n-acetyl-hexosaminidase, and alpha-fucosidase were sensitive indicators and were significantly elevated above control values by day 3 at both doses (P < 0.01).
(15) When irradiated circular DNA, previously nicked by T4 endonuclease V, is briefly exposed to elevated temperature, the DAN becomes susceptible to the action of exonuclease V, and pyrimidine dimers are selectively released.
(16) Finally, it could be observed that elevated osmotic pressures reduced the lysis of isolated secretory granules when bicarbonate ions were present in the incubation medium.
(17) Eight other children (20%) had normal or borderline elevation of CPK-MB fraction and EKG abnormalities combined with abnormal echocardiograms or radionuclide angiograms, and were considered to have sustained cardiac concussion.
(18) Increased iron levels in basal ganglia were generally associated with normal or elevated levels of ferritin immunoreactivity, for example, the substantia nigra in PSP and possibly MSA, and in putamen in MSA.
(19) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
(20) In neither case has a significant elevation in inherited genetic effects or cancer been detected in the offspring of exposed individuals.