(a.) In the front or before others, as regards progress or ideas; as, advanced opinions, advanced thinkers.
(a.) Far on in life or time.
Example Sentences:
(1) This selective review emphasizes advances in neurochemistry which provide a context for current and future research on neurological and psychiatric disorders encountered in clinical practice.
(2) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(3) These results suggest that the pelvic floor is affected by progressive denervation but descent during straining tends to decrease with advancing age.
(4) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
(5) When TSLP was pretreated with TF5 in vitro, the most restorative effects on the decreased MLR were found in hyperplastic stage and the effects were becoming less with the advance of tumor developments.
(6) Finally the advanced automation of the equipment allowed weekly the evaluation of catecholamines and the whole range of their known metabolites in 36 urine samples.
(7) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(8) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(9) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(10) Under a revised deal most people are now being vetted on time, but charges for the service have had to rise from £12 and free vetting for volunteers, to £28 for a standard disclosure and £33 for an advanced disclosure.
(11) Histological and electron-microscopic study of the lungs of 15 patients who had been treated with bleomycin for advanced squamous cell carcinoma demonstrated marked histological changes in nine.
(12) With better understanding of metabolic and compositional requirements, great advances have been made in the area of total parenteral nutrition.
(13) Meanwhile Ed Miliband, the Labour leader, waiting anxiously for news of the scale of the Labour advance in his first nationwide electoral test, will urge the electorate not to be duped by the promise of a coalition mark 2, predicting sham concessions by the Conservatives .
(14) 16 tube (usually a Baker tube) was inserted by gastrostomy and advanced distally into the colon.
(15) Of his number, 266 patients were in the advance stage of their disease while another 42 still had localized cancers.
(16) N-Acetyl-beta-D-glucosaminidase (GAD) activities did not change significantly duringlate fetal, neonatal or young adult stages but increased significantly with advancing age.
(17) Serial antepartum platelet alloantibody quantitation by an enzyme-linked immunoabsorbent assay revealed rising antibody titers during advancing gestation.
(18) Most of the progressive cases were alcoholic, and some showed progression to advanced pancreatitis within 4 years.
(19) Expansion of the cell sheet following attachment, and the fusion of epiblasts advancing toward each other, does not require the presence of mineralocorticoid.
(20) One hundred and sixteen patients with advanced and metastatic adenocarcinoma of the pancreas were randomized to treatment with combined Streptozotocin and 5-fluorouracil or combined Streptozotocin and cyclophosphamide.
Ripe
Definition:
(n.) The bank of a river.
(superl.) Ready for reaping or gathering; having attained perfection; mature; -- said of fruits, seeds, etc.; as, ripe grain.
(superl.) Advanced to the state of fitness for use; mellow; as, ripe cheese; ripe wine.
(superl.) Having attained its full development; mature; perfected; consummate.
(superl.) Maturated or suppurated; ready to discharge; -- said of sores, tumors, etc.
(superl.) Ready for action or effect; prepared.
(superl.) Like ripened fruit in ruddiness and plumpness.
(superl.) Intoxicated.
(v. i.) To ripen; to grow ripe.
(v. t.) To mature; to ripen.
Example Sentences:
(1) 1200 examinations of sonographical demonstrable placental ripeness were done in 552 pregnant women.
(2) I found their remarks a little ripe, if mostly well argued, although Nicholson's characterisation of the characters' default mindset as "Brown people bad, American people good" rather misses the obvious retort: "They wanna kill me, I wanna live."
(3) President Hassan Rouhani , who is visiting New York to speak at the UN general assembly next week, said at a meeting with journalists and media executives on Friday that “conditions were ripe” for his administration to start implementing the agreement, struck in Vienna in July, by the end of the year.
(4) The amount of banana starch not hydrolyzed and absorbed from the human small intestine and therefore passing into the colon may be up to 8 times more than the NSP present in this food and depends on the state of ripeness when the fruit is eaten.
(5) 75 Patients were treated with Prostaglandin-F2 alpha-gel intracervical to ripe the cervix prior to first trimester abortion.
(6) These demographic realities define a policy issue ripe for study.
(7) Her main project is new girl Tai (the late Brittany Murphy) who arrives at school as a clumsy, unconfident "ugly duckling" ripe for making over – allowing the film to indulge in that wonderful 80s teen movie trope: the dressing up montage.
(8) It’s when we have untrusted heads of these old institutions that everything seems ripe for revolution – if someone has the guts and ingenuity to really go for it.
(9) I gaze at it across the street and, as if by magic, I ache with longing, just as I used to in the days when a trip here was the most enjoyable thing I could possibly imagine: when books were all I wanted, when I thought of them as pieces of ripe fruit, waiting to be peeled and devoured.
(10) Some on the left who want Brexit say that the time is not yet ripe.
(11) We think that, after a rather premature condemnation, the time is ripe for a reevaluation and a reevaluation of the ureterosigmoidostomy.
(12) The oogonia pass through seven maturation stages to form the ripe ova.
(13) Total lipid constituted 15% of the dry wt of ripe eggs, 70% of the total lipid being polar lipid with phosphatidylcholine (PC) accounting for almost 90% of the polar lipid.
(14) A child growing up in America witnesses 16,000 murders and 200,000 acts of violence by the time he or she reaches the ripe old age of 18.
(15) Lamicel produced a cervical dilatation and ripeness equal to the syntetic tent without MgSO4.
(16) "The issue is ripe in our country, given the experiences that we know of elsewhere," he added.
(17) There's only so much traipsing sodden hills one person can do; once your Pringles supply from the nearest point of civilisation has been depleted, and anyone with bones ripe for jumping carries the risk of a shared grandparent, it's a wonder more people don't while away the long nights with a spot of leisurely murder.
(18) I think the time is ripe to push these issues into London councils and the London Assembly .
(19) Music in hospitals, he argues, is an area ripe for further exploration.
(20) The relationship between disability in activities of daily living and age-related impairment of physical performance is especially ripe for study.