What's the difference between adverse and pernicious?

Adverse


Definition:

  • (a.) Acting against, or in a contrary direction; opposed; contrary; opposite; conflicting; as, adverse winds; an adverse party; a spirit adverse to distinctions of caste.
  • (a.) Opposite.
  • (a.) In hostile opposition to; unfavorable; unpropitious; contrary to one's wishes; unfortunate; calamitous; afflictive; hurtful; as, adverse fates, adverse circumstances, things adverse.
  • (v. t.) To oppose; to resist.

Example Sentences:

  • (1) There fore, the adverse effects may be induced by such quartz or silicon compounds.
  • (2) The following is a brief review of the history, mechanism of action, and potential adverse effects of neuromuscular blockers.
  • (3) This modified endocrine activity in brook trout may reflect adjustment to adverse external ionic conditions.
  • (4) The AL plus EA produced significantly greater adverse effects than with SFO plus EA.
  • (5) Mild, significant improvement was noted in one of the hearing components, "attenuation," and an adverse effect was shown on "distortion," owing to noise.
  • (6) Spontaneous reports of suspected adverse reactions may be the only way of revealing very rare events but they present great difficulties of rational interpretation.
  • (7) Adverse outcomes were reported more frequently by consultant physicians, by those who 'titrated' the intravenous sedative, and by those who used an additional intravenous agent, but were reported equally frequently by endoscopists using midazolam and endoscopists using diazepam.
  • (8) Only an extensive knowledge of the various mechanisms and pharmacologic agents that can be used to prevent or treat these adverse reactions will allow the physician to approach the problem scientifically and come to a reasonable solution for the patient.
  • (9) The prognosis was adversely affected by obesity, preoperative flexion contracture of 30 degrees or more, wound-healing problems, wound infection, and postoperative manipulation under general anesthesia.
  • (10) One thousand singleton low-risk pregnancies were cross-sectionally studied at 36-40 weeks gestation with continuous-wave Doppler ultrasonography in order to assess its usefulness as an antepartum monitoring technique for the identification of fetuses at risk of developing an adverse outcome.
  • (11) The relatively high concentrations of desethylchloroquine and bisdesethylchloroquine found during chronic treatment show the need for more information about the therapeutic value and adverse effects of the metabolites.
  • (12) Urinary incontinence present between 7 and 10 days after stroke was the most important adverse prognostic factor both for survival and for recovery of function.
  • (13) Long-term treatment with agents that stimulate the beta-receptor (prenalterol and pirbuterol) has not proved to be useful in the treatment of chronic heart failure; moreover, prolonged treatment with beta-agonists (dobutamine and pirbuterol) may adversely affect survival.
  • (14) Since ASA has a greater potential for adverse effects, paracetamol is increasingly preferred to ASA, particularly in children.
  • (15) When a product is selected for a patient, consideration should be given to necessity, efficacy, adverse effects, and cost-effectiveness.
  • (16) The presence of prostatic invasion either into the stroma or involving prostatic ducts and acini only had no adverse effect on outcome.
  • (17) Oocytes obtained by laparoscopy were compared with those obtained under ultrasonic guidance to determine whether CO2 exposure had any adverse effect.
  • (18) It is mentioned that the lack of a valuable status for industrial physicians may adversely affect the evolution of training programs in Switzerland.
  • (19) Alternatively, the data presented herein strongly suggest that diets containing conventional quantities of fat, in which saturated fat is replaced by unsaturated fat and dietary cholesterol reduced, would result in the desired reductions to total and low-density lipoprotein cholesterol concentrations without the adverse effects of increased postprandial glucose and insulin concentrations, increased fasting and postprandial total and very-low-density lipoprotein triglyceride concentrations, and decreased fasting high-density lipoprotein cholesterol concentrations.
  • (20) "I have to say that it is my expectation that they probably can be, because the data that we have to date is unlikely to show an adverse impact."

Pernicious


Definition:

  • (a.) Having the quality of injuring or killing; destructive; very mischievous; baleful; malicious; wicked.
  • (a.) Quick; swift (to burn).

Example Sentences:

  • (1) To investigate the possibility that an abnormality of gastric emptying exists in duodenal ulcer and to determine if such an abnormality persists after ulcer healing, scintigraphic gastric emptying measurements were undertaken in 16 duodenal ulcer patients before, during, and after therapy with cimetidine; in 12 patients with pernicious anemia, and in 12 control subjects.
  • (2) Urinary excretion of (60)Co radioactivity in pernicious anemia patients after oral administration of (60)Co-vitamin B(12) bound to freshly prepared (125)I-labeled IF was similar to that obtained with noniodinated intrinsic factor.
  • (3) Antibodies to parietal cells were found in 5 cases and 4 patients with pernicious anemia were detected.
  • (4) Reticulocytes of patients with pernicious anaemia on treatment and with haemolytic anaemia were shown to have higher folate levels than their corresponding mature cells.
  • (5) Immunofluorescence tests on 94 human sera reacting with rat gastric parietal cells revealed that 41 (44%) of the sera contained antibody to a rat parietal cell antigen that was distinct from the pernicious anaemia autoantigen.
  • (6) In pernicious anaemia the amount of enzyme is reduced and on this hypothesis the regulatory function impaired.
  • (7) Six patients without nervous system involvement had normal EEGs, 10 patients with spinal cord or peripheral nervous system involvement had normal or minimally abnormal EEGs, 17 of 19 patients with evidence of mental dysfunction had abnormal EEGs with the most consistent finding being an excess of theta slowing, and 19 patients with pernicious anemia and other neurologic diseases showed EEG findings reflecting the complicating disease process.
  • (8) This article details the pernicious odontostomatological effects provoked by antitumorous and immunosuppressive medication.
  • (9) This week, the resilience of Italy’s most pernicious problem – the mafia – was exposed once again when it was announced that Corleone’s town council was being dissolved by the order of Rome because it had been infiltrated by organised crime.
  • (10) Thus the Type A pattern of gastritis (autoimmune) seen in patients with pernicious anaemia is only rarely associated with Campylobacter like organisms.
  • (11) Thus, the processing of progastrin adjacent to the active site of gastrin is more restrictively controlled than N-terminal processing during G-cell hypersecretion associated with pernicious anemia.
  • (12) The early improvement in marrow morphology in patients with pernicious anaemia was greater with 1000 mug than with 5 mug doses of cyanocobalamin.
  • (13) They were found to have pernicious anemia (PA) and normal adrenal functions.
  • (14) The EEG was also a good indicator for detecting and confirming other intracranial disease processes unrelated to pernicious anemia.
  • (15) The endocrine tumours corresponded to the gastric carcinoids found in patients with long-lasting hypergastrinaemia due to pernicious anaemia or with a gastrinoma as part of the MEN I syndrome.
  • (16) Two vitiligo patients were hypergastrinaemic suggesting latent pernicious anaemia.
  • (17) 27 patients with pernicious anaemia, followed for a long period, were consecutively treated with three different vitamin B12 preparations, while during intervening period no therapy was given until signs of B12 deficiency developed.
  • (18) Sixteen control subjects, 13 patients with pernicious anaemia, and four who had had total gastrectomy were studied.
  • (19) And so while it’s particularly pernicious that some parents pay for months, sometimes years, of tutoring to get their child through an exam that they might well otherwise fail, I know it’s because they are desperate to secure for their child any extra benefit going in a country that is becoming ever more unequal.
  • (20) This policy, which prevents many travellers and overseas residents from benefitting from one of the most effective prophylactic treatments on the market today, thereby indirectly causing a number of pernicious cases of malaria, is based on the unfounded, unproved premise that wide use of this drug would foster the development of méfloquine-resistance or on side-effects, which are in fact rarely of any consequence and always curable.