(n.) Relationship by marriage (as between a husband and his wife's blood relations, or between a wife and her husband's blood relations); -- in contradistinction to consanguinity, or relationship by blood; -- followed by with, to, or between.
(n.) Kinship generally; close agreement; relation; conformity; resemblance; connection; as, the affinity of sounds, of colors, or of languages.
(n.) Companionship; acquaintance.
(n.) That attraction which takes place, at an insensible distance, between the heterogeneous particles of bodies, and unites them to form chemical compounds; chemism; chemical or elective affinity or attraction.
(n.) A relation between species or highe/ groups dependent on resemblance in the whole plan of structure, and indicating community of origin.
(n.) A superior spiritual relationship or attraction held to exist sometimes between persons, esp. persons of the opposite sex; also, the man or woman who exerts such psychical or spiritual attraction.
Example Sentences:
(1) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(2) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(3) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(4) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(7) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(8) ASF-II was purified to apparent homogeneity by using concanavalin A-agarose affinity chromatography, DEAE-cellulose chromatography, alumina gel adsorption, and isoelectric focussing techniques.
(9) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(10) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(11) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(12) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(13) Only estrogenic hormones are bound with high affinity.
(14) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
(15) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(16) Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system.
(17) In lactate medium the capacity of each AIB carrier is unchanged but its affinity is reduced to one-third.
(18) The telencephalon of teleost fish shows high affinity uptake for D-[3H]aspartate, intermediate levels of GABAergic markers and low levels of cholinergic enzymes.
(19) In all immunized rabbits the antisera obtained with the 7 alpha-derivative had a higher affinity and a narrower specificity than the antiserum obtained with the 7 beta-derivative.
(20) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
Force
Definition:
(v. t.) To stuff; to lard; to farce.
(n.) A waterfall; a cascade.
(n.) Strength or energy of body or mind; active power; vigor; might; often, an unusual degree of strength or energy; capacity of exercising an influence or producing an effect; especially, power to persuade, or convince, or impose obligation; pertinency; validity; special signification; as, the force of an appeal, an argument, a contract, or a term.
(n.) Power exerted against will or consent; compulsory power; violence; coercion.
(n.) Strength or power for war; hence, a body of land or naval combatants, with their appurtenances, ready for action; -- an armament; troops; warlike array; -- often in the plural; hence, a body of men prepared for action in other ways; as, the laboring force of a plantation.
(n.) Strength or power exercised without law, or contrary to law, upon persons or things; violence.
(n.) Validity; efficacy.
(n.) Any action between two bodies which changes, or tends to change, their relative condition as to rest or motion; or, more generally, which changes, or tends to change, any physical relation between them, whether mechanical, thermal, chemical, electrical, magnetic, or of any other kind; as, the force of gravity; cohesive force; centrifugal force.
(n.) To constrain to do or to forbear, by the exertion of a power not resistible; to compel by physical, moral, or intellectual means; to coerce; as, masters force slaves to labor.
(n.) To compel, as by strength of evidence; as, to force conviction on the mind.
(n.) To do violence to; to overpower, or to compel by violence to one;s will; especially, to ravish; to violate; to commit rape upon.
(n.) To obtain or win by strength; to take by violence or struggle; specifically, to capture by assault; to storm, as a fortress.
(n.) To impel, drive, wrest, extort, get, etc., by main strength or violence; -- with a following adverb, as along, away, from, into, through, out, etc.
(n.) To put in force; to cause to be executed; to make binding; to enforce.
(n.) To exert to the utmost; to urge; hence, to strain; to urge to excessive, unnatural, or untimely action; to produce by unnatural effort; as, to force a consient or metaphor; to force a laugh; to force fruits.
(n.) To compel (an adversary or partner) to trump a trick by leading a suit of which he has none.
(n.) To provide with forces; to reenforce; to strengthen by soldiers; to man; to garrison.
(n.) To allow the force of; to value; to care for.
(v. i.) To use violence; to make violent effort; to strive; to endeavor.
(v. i.) To make a difficult matter of anything; to labor; to hesitate; hence, to force of, to make much account of; to regard.
(v. i.) To be of force, importance, or weight; to matter.
Example Sentences:
(1) They’re no crack force either; many are rather portly!
(2) I want to be clear; the American forces that have been deployed to Iraq do not and will not have a combat mission,” said Obama in a speech to troops at US Central Command headquarters in Florida.
(3) In early 2000, during the first months of Vladimir Putin’s presidency, Babitsky was kidnapped by Russian forces and disappeared for many weeks.
(4) Historical analysis shows that institutions and special education services spring from common, although not identical, societal and philosophical forces.
(5) Further, the maximal increase in force of contraction was measured using papillary muscle strips from some of these patients.
(6) "What has made that worse is the disingenuous way the force has defended their actions.
(7) Patrice Evra Evra Handed a five-match international ban for his part in the France squad’s mutiny against Raymond Domenech at the 2010 World Cup, it took Evra almost a year to force his way back in.
(8) DI James Faulkner of Great Manchester police said: “The men and women working in the factory have told us that they were subjected to physical and verbal assaults at the hands of their employers and forced to work more than 80-hours before ending up with around £25 for their week’s work.
(9) There have been numerous documented cases of people being forced to seek hospital treatment after eating meat contaminated with high concentrations of clenbuterol.
(10) Peak Expiratory Flow and Forced Expiratory Mean Flows in the ranges 0-25%, 25-50% and 50-75% of Forced Vital Capacity were significantly reduced in animals exposed to gasoline exhaust fumes, whereas the group exposed to ethanol exhaust fumes did not differ from the control group.
(11) She knows you can’t force the opposition to submit to your point of view.
(12) However in the deciduous teeth from which the successional tooth germs were removed, the processes of tooth resorption was very different in individuals, the difference between tooth resorption in normal occlusal force and in decreased occlusal force was not clear.
(13) In a series of compounds with H2-antihistaminic activity, a conformational analysis was performed based on force field calculations.
(14) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
(15) In order for the club to grow and sustain its ability to be a competitive force in the Premier League, the board has made a number of decisions which will strengthen the club, support the executive team, manager and his staff and enhance shareholder return.
(16) Of great influence on the results of measurements are preparation and registration (warm-up-time, amplification, closeness of pressure-system, unhurt catheters), factors relating to equipment and methods (air-bubbles in pressure-system, damping by filters, continuous infusion of the micro-catheter, level of zero-pressure), factors which occur during intravital measurement (pressure-drop along the arteria pulmonalis, influence of normal breathing, great intrapleural pressure changes, pressure damping in the catheter by thrombosis and external disturbances) and last not least positive and negative acceleration forces, which influence the diastolic and systolic pulmonary artery pressure.
(17) These reflexes can function to limit forces applied to a leg and provide compensatory adjustments in other legs.
(18) Five investigations into the force are being carried out by the IPCC.
(19) The data indicate that with force present for 10% of the time (1:9), there was little or no effect on eruption rate.
(20) The mechanical forces involved in neurite extension have begun to be quantified, and interactions between the actin and microtubule systems are being further characterized.