(v. t.) To make heavy or heavier; to add to; to increase.
(v. t.) To make worse, or more severe; to render less tolerable or less excusable; to make more offensive; to enhance; to intensify.
(v. t.) To give coloring to in description; to exaggerate; as, to aggravate circumstances.
(v. t.) To exasperate; to provoke; to irritate.
Example Sentences:
(1) The major acute postoperative finding was aggravation of preexisting pharyngeal dysfunction.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) This experimental study shows that vitamin A in high doses has an adjuvant effect, that is aggravating considerably the immunologic arthritis induced in the Wistar rat.
(4) Nine factors have been isolated whose varying combinations were most contributory to the risk of the development of CS in the studied population: cardiac diseases, transient disorder of the cerebral circulation, arterial hypertension, atherosclerosis, aggravated heredity for cardiovascular diseases, intermittent claudication, diabetes mellitus, systematic alcohol abuse, and hypodynamia.
(5) A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily.
(6) Existing visual field defects in three patients were slightly aggravated and in four patients, with a pathological optic disc, visual field loss developed.
(7) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
(8) As a result of a psychopathological total systems analysis of the debut of exogenously aggravated and nonaggravated paranoid schizophrenia the authors have revealed a significant interrelationship allowing the characterization of both general regularities of the "background" effect and individual characteristics secondary to a concrete nature of exogenous impact.
(9) Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
(10) Uncontrolled diabetes mellitus can aggravate the hyperlipidaemia associated with this disorder, presumably by increasing triglyceride synthesis and reducing very low density lipoprotein catabolism by lipoprotein lipase.
(11) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(12) A definite correlation was established between the disease and the character of work and specificity of the working postures: a long stay in a bent position aggravated by the pressure of the apron strap weighing 8-10 kg on the lumbar part of the spine.
(13) Empirical studies suggest the following main conclusions: functional somatic symptoms are extremely common; a large proportion appear to be caused by physiologic activity and tend to be aggravated by emotion.
(14) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(15) This situation can lead to an aggravation of degenerative complications.
(16) He believes there are several factors that could aggravate extremists, other than the videos.
(17) Direct relationship between the increase of blood fibrinolytic activity and the aggravation of the vascular degeneration could not be observed in this experiment.
(18) Wash-out experiments show that the sugars prevent the aggravation of mediator release by a binding of sugar to the basophil cell membrane, thereby causing a blockade of binding sites responsible for the potentiating effect of virus.
(19) We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuclear leukocyte oxidants or hydrogen peroxide (H2O2).
(20) However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Deteriorate
Definition:
(v. t.) To make worse; to make inferior in quality or value; to impair; as, to deteriorate the mind.
(v. i.) To grow worse; to be impaired in quality; to degenerate.
Example Sentences:
(1) It is followed by rapid neurobehavioral deterioration in late infancy or early childhood, a developmental arrest, plateauing, and then either a course of retarded development or continued deterioration.
(2) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(3) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(4) "There is … a risk that the political, trade, and gas frictions with Russia could lead to strong deterioration in economic relations between the two countries, with a significant drop in Ukraine's exports to and imports from Russia.
(5) This suggests that there was a deterioration of the vasoconstrictor response and indicated a possible effect of heat at the receptor or effector level.
(6) Four patients had previously been diverted and the other six were reconstructed because of intractable incontinence or deteriorating renal function.
(7) Finally, these cases support the existence of a therapeutic upper limit for desipramine plasma concentrations, above which clinical deterioration occurs.
(8) In view of the high mortality every clinical deterioration of patients with cirrhosis should alert the physician of the presence of SBP.
(9) The authors present a boy with a sudden onset a large intracranial hematoma causing rapid neurologic deterioration.
(10) The data suggest late hemodynamic deterioration after 48 hours of IABC.
(11) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(12) The dilemma focuses on whether the obliteration or removal of the cystic areas will benefit or cause further deterioration of the patient's condition.
(13) Bacteriuria was not associated with deteriorating renal function determined by serial plasma creatinine estimations.
(14) The deteriorating situation would worsen if ministers pressed ahead with another controversial Lansley policy – that of abolishing the cap on the amount of income semi-independent foundation trust hospitals can make by treating private patients.
(15) During a postoperative follow-up period of 1 to 3 years, no further deterioration has been observed and magnetic resonance studies have demonstrated a space filled with cerebrospinal fluid (CSF) around the lumbosacral cord.
(16) Use of sunglasses that block all ultraviolet radiation and severely attenuate high-energy visible radiation will slow the pace of ocular deterioration and delay the onset of age-related disease, thereby reducing its prevalence.
(17) Sechin warned the west earlier this week that expanding sanctions over Russia's annexation of Ukraine's Crimea region would only make the political situation deteriorate further, according to Reuters.
(18) Rates of clinical deterioration and frequencies of attacks were not significantly different between treated and control groups.
(19) In a follow-up of 17 HIV-positive subjects, nine presented deteriorated reflexes in the tests and higher IgG immune complex levels.
(20) However, these good results deteriorated on longer follow-up and were not expected to be permanent.