(v. t.) To make heavy or heavier; to add to; to increase.
(v. t.) To make worse, or more severe; to render less tolerable or less excusable; to make more offensive; to enhance; to intensify.
(v. t.) To give coloring to in description; to exaggerate; as, to aggravate circumstances.
(v. t.) To exasperate; to provoke; to irritate.
Example Sentences:
(1) The major acute postoperative finding was aggravation of preexisting pharyngeal dysfunction.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) This experimental study shows that vitamin A in high doses has an adjuvant effect, that is aggravating considerably the immunologic arthritis induced in the Wistar rat.
(4) Nine factors have been isolated whose varying combinations were most contributory to the risk of the development of CS in the studied population: cardiac diseases, transient disorder of the cerebral circulation, arterial hypertension, atherosclerosis, aggravated heredity for cardiovascular diseases, intermittent claudication, diabetes mellitus, systematic alcohol abuse, and hypodynamia.
(5) A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily.
(6) Existing visual field defects in three patients were slightly aggravated and in four patients, with a pathological optic disc, visual field loss developed.
(7) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
(8) As a result of a psychopathological total systems analysis of the debut of exogenously aggravated and nonaggravated paranoid schizophrenia the authors have revealed a significant interrelationship allowing the characterization of both general regularities of the "background" effect and individual characteristics secondary to a concrete nature of exogenous impact.
(9) Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
(10) Uncontrolled diabetes mellitus can aggravate the hyperlipidaemia associated with this disorder, presumably by increasing triglyceride synthesis and reducing very low density lipoprotein catabolism by lipoprotein lipase.
(11) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(12) A definite correlation was established between the disease and the character of work and specificity of the working postures: a long stay in a bent position aggravated by the pressure of the apron strap weighing 8-10 kg on the lumbar part of the spine.
(13) Empirical studies suggest the following main conclusions: functional somatic symptoms are extremely common; a large proportion appear to be caused by physiologic activity and tend to be aggravated by emotion.
(14) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(15) This situation can lead to an aggravation of degenerative complications.
(16) He believes there are several factors that could aggravate extremists, other than the videos.
(17) Direct relationship between the increase of blood fibrinolytic activity and the aggravation of the vascular degeneration could not be observed in this experiment.
(18) Wash-out experiments show that the sugars prevent the aggravation of mediator release by a binding of sugar to the basophil cell membrane, thereby causing a blockade of binding sites responsible for the potentiating effect of virus.
(19) We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuclear leukocyte oxidants or hydrogen peroxide (H2O2).
(20) However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Extenuate
Definition:
(v. t.) To make thin or slender; to draw out so as to lessen the thickness.
(v. t.) To lessen; to palliate; to lessen or weaken the force of; to diminish the conception of, as crime, guilt, faults, ills, accusations, etc.; -- opposed to aggravate.
(v. t.) To lower or degrade; to detract from.
(v. i.) To become thinner; to make excuses; to advance palliating considerations.
(a.) Thin; slender.
Example Sentences:
(1) Can't put a finger on it, though there were obvious extenuating personal circumstances in the case of the two most anticipated acts (Gaga and Cole).
(2) It is our opinion that except for certain extenuating circumstances, the procedure of choice for carcinoma of the breast is either a modified or standard radical mastectomy.
(3) These negative feelings and negative self-images are exploited so as to appease the superego in the face of one's hostile aggression: that one is justified, that there are extenuating circumstances for one's hatred and destructiveness.
(4) Other recent IOM research shows that the majority had not intended to travel to Europe when leaving home, but had been forced to change their destinations due to extenuating circumstances such as the Libyan civil war.
(5) The intravenous urogram, including the initial plain film, remains the primary diagnostic modality and, in the absence of extenuating clinical features, is often the sole test required to make a decision regarding the best therapeutic modality.
(6) Uruguay recently legalised first trimester interventions, while Colombia, Brazil and Argentina allow abortion in rape and other extenuating circumstances.
(7) "What I am saying is that I don't think everyone should be chucked into prison regardless of the circumstances, with no discretion, no exceptions and no extenuating circumstances.
(8) Thirdly, it starts to admit extenuations and exceptions.
(9) These changes develop by an increase in mean arterial pressure, the reduction of the sympathetic activity, and probably of an extenuation of the splanchnic vasodilation.
(10) Hence, chronic administration of lithium leads to potentiation in its action of the serotonin-negative and central adreno-negative componets and to extenuating the peripheral adreno-negative component.
(11) "Due to extenuating circumstances, Secret Cinema is unable to receive guests at tonight's show of Secret Cinema presents Back to the Future" the statement read.
(12) The government already has precious little trust in grassroots British Muslim circles on their preventing extremism agenda – and if the suggested plans are true then that disconnect will simply extenuate the circumstances, making us all that much less safe.
(13) Subjects' rating indicated that (a) biology was judged important for explaining negative moods occurring premenstrually: (b) inconsistency between mood and environment produced more internal (personality) attributions, while consistency enhanced external attributions; and (c) emotionally expressive behavior was thought to reflect underlying personality dispositions despite extenuating situational factors (assumed personal causation).
(14) Both had very extenuating circumstances making complete repair inappropriate.
(15) Adam's sin is perhaps mitigated by the extenuating circumstance that he didn't exist.
(16) The population studies as representative of psychiatric extenuation are a personal consecutive sample of court referrals for formal evaluation undertaken in a psychiatric hospital unit.
(17) Only extenuating circumstances justify these risks when general anesthesia is available.
(18) In some cases, there were extenuating circumstances which, when combined with obstetrical intervention, resulted in an increase in mortality.
(19) Secret Cinema said that the cancellation was due to "extenuating circumstances".
(20) The 49ers are in his backyard.” Martin must pass a physical for the trade to be officially executed, but that’s expected for be a formality for the 42nd overall pick in the 2012 draft, who will now hope to fulfil his potential in a new environment after underperforming - albeit with extenuating circumstances - in Miami.