(v. t.) To make heavy or heavier; to add to; to increase.
(v. t.) To make worse, or more severe; to render less tolerable or less excusable; to make more offensive; to enhance; to intensify.
(v. t.) To give coloring to in description; to exaggerate; as, to aggravate circumstances.
(v. t.) To exasperate; to provoke; to irritate.
Example Sentences:
(1) The major acute postoperative finding was aggravation of preexisting pharyngeal dysfunction.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) This experimental study shows that vitamin A in high doses has an adjuvant effect, that is aggravating considerably the immunologic arthritis induced in the Wistar rat.
(4) Nine factors have been isolated whose varying combinations were most contributory to the risk of the development of CS in the studied population: cardiac diseases, transient disorder of the cerebral circulation, arterial hypertension, atherosclerosis, aggravated heredity for cardiovascular diseases, intermittent claudication, diabetes mellitus, systematic alcohol abuse, and hypodynamia.
(5) A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily.
(6) Existing visual field defects in three patients were slightly aggravated and in four patients, with a pathological optic disc, visual field loss developed.
(7) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
(8) As a result of a psychopathological total systems analysis of the debut of exogenously aggravated and nonaggravated paranoid schizophrenia the authors have revealed a significant interrelationship allowing the characterization of both general regularities of the "background" effect and individual characteristics secondary to a concrete nature of exogenous impact.
(9) Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
(10) Uncontrolled diabetes mellitus can aggravate the hyperlipidaemia associated with this disorder, presumably by increasing triglyceride synthesis and reducing very low density lipoprotein catabolism by lipoprotein lipase.
(11) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(12) A definite correlation was established between the disease and the character of work and specificity of the working postures: a long stay in a bent position aggravated by the pressure of the apron strap weighing 8-10 kg on the lumbar part of the spine.
(13) Empirical studies suggest the following main conclusions: functional somatic symptoms are extremely common; a large proportion appear to be caused by physiologic activity and tend to be aggravated by emotion.
(14) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(15) This situation can lead to an aggravation of degenerative complications.
(16) He believes there are several factors that could aggravate extremists, other than the videos.
(17) Direct relationship between the increase of blood fibrinolytic activity and the aggravation of the vascular degeneration could not be observed in this experiment.
(18) Wash-out experiments show that the sugars prevent the aggravation of mediator release by a binding of sugar to the basophil cell membrane, thereby causing a blockade of binding sites responsible for the potentiating effect of virus.
(19) We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuclear leukocyte oxidants or hydrogen peroxide (H2O2).
(20) However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Increase
Definition:
(v. i.) To become greater or more in size, quantity, number, degree, value, intensity, power, authority, reputation, wealth; to grow; to augment; to advance; -- opposed to decrease.
(v. i.) To multiply by the production of young; to be fertile, fruitful, or prolific.
(v. i.) To become more nearly full; to show more of the surface; to wax; as, the moon increases.
(v. t.) To augment or make greater in bulk, quantity, extent, value, or amount, etc.; to add to; to extend; to lengthen; to enhance; to aggravate; as, to increase one's possessions, influence.
(v. i.) Addition or enlargement in size, extent, quantity, number, intensity, value, substance, etc.; augmentation; growth.
(v. i.) That which is added to the original stock by augmentation or growth; produce; profit; interest.
(v. i.) Progeny; issue; offspring.
(v. i.) Generation.
(v. i.) The period of increasing light, or luminous phase; the waxing; -- said of the moon.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) Synthesis of choline esterase on the medium with acetylcholine at a concentration of 1% was increased more than twofold upon addition of glucose at a concentration of 0.1%.
(3) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(4) Correction for within-person variation in urinary excretion increased this partial correlation coefficient between intake and excretion to 0.59 (95% CI = 0.03 to 0.87).
(5) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(6) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(7) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(8) In conclusion, in S-rats a glucose-stimulated insulin release is accompanied by an increase in IBF, but this is not observed in P-rats.
(9) Following in vitro C activation in NHS by delta IgG, the 40 KD C4d component increased markedly.
(10) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(11) At the early phase of the sensitization a T-cell response was seen in vitro, characterized by an increased spleen but no peripheral blood lymphocyte reactivity to T-cell mitogens at the same time as increased reactivity to the sensitizing antigen was detected.
(12) Maximum increases in portal plasma secretin concentrations of 143, 146 and 190% and maximum increases in VIP of 116, 155 and 147% after, respectively, intraduodenal 0.1 M NaHCO3, 0.1 M Na2CO3, and 0.025 M NaOH were found.
(13) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(14) The cross sectional area of the aortic lumen was gradually decreased while the length of the stenotic lesion gradually increased by using strips with different width.
(15) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(16) Both lymph flow from cannulated pancreatico-duodenal lymphatics and intralymphatic pressure in the non-transected ones increased significantly.
(17) Increased dietary protein intake led to increased MDA per nephron, increased urinary excretion of MDA, and increased MDA per milligram protein in subtotally nephrectomized animals, and markedly increased the glutathione redox ratio.
(18) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(19) However, four of ten young adult outer arm (relatively sun-exposed) and one of ten young adult inner arm (relatively sun-protected) fibroblasts lines increased their saturation density in response to retinoic acid.
(20) Addition of phospholipase A2 from Vipera russelli venom led to a significant increase in the activity of guanylate cyclase in various rat organs.