(v. t.) To make heavy or heavier; to add to; to increase.
(v. t.) To make worse, or more severe; to render less tolerable or less excusable; to make more offensive; to enhance; to intensify.
(v. t.) To give coloring to in description; to exaggerate; as, to aggravate circumstances.
(v. t.) To exasperate; to provoke; to irritate.
Example Sentences:
(1) The major acute postoperative finding was aggravation of preexisting pharyngeal dysfunction.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) This experimental study shows that vitamin A in high doses has an adjuvant effect, that is aggravating considerably the immunologic arthritis induced in the Wistar rat.
(4) Nine factors have been isolated whose varying combinations were most contributory to the risk of the development of CS in the studied population: cardiac diseases, transient disorder of the cerebral circulation, arterial hypertension, atherosclerosis, aggravated heredity for cardiovascular diseases, intermittent claudication, diabetes mellitus, systematic alcohol abuse, and hypodynamia.
(5) A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily.
(6) Existing visual field defects in three patients were slightly aggravated and in four patients, with a pathological optic disc, visual field loss developed.
(7) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
(8) As a result of a psychopathological total systems analysis of the debut of exogenously aggravated and nonaggravated paranoid schizophrenia the authors have revealed a significant interrelationship allowing the characterization of both general regularities of the "background" effect and individual characteristics secondary to a concrete nature of exogenous impact.
(9) Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
(10) Uncontrolled diabetes mellitus can aggravate the hyperlipidaemia associated with this disorder, presumably by increasing triglyceride synthesis and reducing very low density lipoprotein catabolism by lipoprotein lipase.
(11) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(12) A definite correlation was established between the disease and the character of work and specificity of the working postures: a long stay in a bent position aggravated by the pressure of the apron strap weighing 8-10 kg on the lumbar part of the spine.
(13) Empirical studies suggest the following main conclusions: functional somatic symptoms are extremely common; a large proportion appear to be caused by physiologic activity and tend to be aggravated by emotion.
(14) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(15) This situation can lead to an aggravation of degenerative complications.
(16) He believes there are several factors that could aggravate extremists, other than the videos.
(17) Direct relationship between the increase of blood fibrinolytic activity and the aggravation of the vascular degeneration could not be observed in this experiment.
(18) Wash-out experiments show that the sugars prevent the aggravation of mediator release by a binding of sugar to the basophil cell membrane, thereby causing a blockade of binding sites responsible for the potentiating effect of virus.
(19) We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuclear leukocyte oxidants or hydrogen peroxide (H2O2).
(20) However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Relapse
Definition:
(v. i.) To slip or slide back, in a literal sense; to turn back.
(v. i.) To slide or turn back into a former state or practice; to fall back from some condition attained; -- generally in a bad sense, as from a state of convalescence or amended condition; as, to relapse into a stupor, into vice, or into barbarism; -- sometimes in a good sense; as, to relapse into slumber after being disturbed.
(v. i.) To fall from Christian faith into paganism, heresy, or unbelief; to backslide.
(v.) A sliding or falling back, especially into a former bad state, either of body or morals; backsliding; the state of having fallen back.
(v.) One who has relapsed, or fallen back, into error; a backslider; specifically, one who, after recanting error, returns to it again.
Example Sentences:
(1) Nine of 14 patients studied for documented clinical relapse had positive repeat studies.
(2) The most common reasons cited for relapse included craving, social situations, stress, and nervousness.
(3) Mitoses of nuclei of myocytes of the left ventricle of the heart observed in two elderly people who had died of extensive relapsing infarction are described.
(4) Due to continued disease relapse in this group (four of eight patients), long-term survivors should not be identified for a minimum of 3.5 years from the time of initial therapy.
(5) The plasma levels of atrial natriuretic factor (ANF) were measured both during relapse and remission in 8 patients with idiopathic, minimal-lesion nephrotic syndrome.
(6) With a median follow-up of 6 years, 32 (20%) of 156 patients who achieved complete remission have relapsed.
(7) In Stage I, seven relapses (relapse rate 6%) occurred after irradiation; three of them were cured with second-line therapies.
(8) The relapse was 80% in the sagittal plane, 70% in the transverse plane, and 12% in the vertical plane.
(9) Therefore, a mortality analysis of overall survival time alone may conceal important differences between the forces of mortality (hazard functions) associated with distinct states of active disease, for example pre-remission state and first relapse.
(10) High concordance was observed between a positive test and relapse during the period of study (chi-square = 27.53, P less than 0.001).
(11) These results suggest that a lowered basal energy expenditure and a reduced glucose-induced thermogenesis contribute to the positive energy balance which results in relapse of body weight gain after cessation of a hypocaloric diet.
(12) Between January 1979 and April 1983, 113 children undergoing their first relapse of acute lymphoid leukemia (ALL) at any site were registered in Pediatric Oncology Group study 7834; 98 were eligible and evaluable.
(13) We measured CSF immunoreactive myelin basic protein (MBP), a marker of acute myelin damage, and sIL-2R levels in the CSF from 11 patients with active relapsing remitting (RR) MS, five with stable RR MS, eight with chronic progressive (CP) MS, five with other neurologic diseases, and three normal controls.
(14) Of all solid tumors only nine occurred in relapse-free patients.
(15) Seven patients relapsed after a CY-induced remission, but 5 of them became steroid responsive.
(16) Many reports of thyroid stimulating immunoglobulins (TSI) in relation to treatment of Graves' disease have been published and with variable results concerning prediction of permanent remission or relapse after therapy.
(17) Surgical and pathologic staging can identify a subset of surgically treated rectal cancer patients at high risk for tumor relapse and death.
(18) These results suggest that the bacterium may not play an important pathogenetic role in ulcer healing and relapse, when patients are managed using an H2-blocker.
(19) Several treatment regimes were assessed, and of these it appeared that sulphamethizole 1g three times a day was most effective, both in terms of a lower rate of relapse of infection and also a low incidence of side effects.
(20) After effective treatment the level fell and rose again 10 months prior to the conventional clinical diagnosis of relapse.