(v. t.) To make heavy or heavier; to add to; to increase.
(v. t.) To make worse, or more severe; to render less tolerable or less excusable; to make more offensive; to enhance; to intensify.
(v. t.) To give coloring to in description; to exaggerate; as, to aggravate circumstances.
(v. t.) To exasperate; to provoke; to irritate.
Example Sentences:
(1) The major acute postoperative finding was aggravation of preexisting pharyngeal dysfunction.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) This experimental study shows that vitamin A in high doses has an adjuvant effect, that is aggravating considerably the immunologic arthritis induced in the Wistar rat.
(4) Nine factors have been isolated whose varying combinations were most contributory to the risk of the development of CS in the studied population: cardiac diseases, transient disorder of the cerebral circulation, arterial hypertension, atherosclerosis, aggravated heredity for cardiovascular diseases, intermittent claudication, diabetes mellitus, systematic alcohol abuse, and hypodynamia.
(5) A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily.
(6) Existing visual field defects in three patients were slightly aggravated and in four patients, with a pathological optic disc, visual field loss developed.
(7) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
(8) As a result of a psychopathological total systems analysis of the debut of exogenously aggravated and nonaggravated paranoid schizophrenia the authors have revealed a significant interrelationship allowing the characterization of both general regularities of the "background" effect and individual characteristics secondary to a concrete nature of exogenous impact.
(9) Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
(10) Uncontrolled diabetes mellitus can aggravate the hyperlipidaemia associated with this disorder, presumably by increasing triglyceride synthesis and reducing very low density lipoprotein catabolism by lipoprotein lipase.
(11) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(12) A definite correlation was established between the disease and the character of work and specificity of the working postures: a long stay in a bent position aggravated by the pressure of the apron strap weighing 8-10 kg on the lumbar part of the spine.
(13) Empirical studies suggest the following main conclusions: functional somatic symptoms are extremely common; a large proportion appear to be caused by physiologic activity and tend to be aggravated by emotion.
(14) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(15) This situation can lead to an aggravation of degenerative complications.
(16) He believes there are several factors that could aggravate extremists, other than the videos.
(17) Direct relationship between the increase of blood fibrinolytic activity and the aggravation of the vascular degeneration could not be observed in this experiment.
(18) Wash-out experiments show that the sugars prevent the aggravation of mediator release by a binding of sugar to the basophil cell membrane, thereby causing a blockade of binding sites responsible for the potentiating effect of virus.
(19) We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuclear leukocyte oxidants or hydrogen peroxide (H2O2).
(20) However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Strain
Definition:
(n.) Race; stock; generation; descent; family.
(n.) Hereditary character, quality, or disposition.
(n.) Rank; a sort.
(a.) To draw with force; to extend with great effort; to stretch; as, to strain a rope; to strain the shrouds of a ship; to strain the cords of a musical instrument.
(a.) To act upon, in any way, so as to cause change of form or volume, as forces on a beam to bend it.
(a.) To exert to the utmost; to ply vigorously.
(a.) To stretch beyond its proper limit; to do violence to, in the matter of intent or meaning; as, to strain the law in order to convict an accused person.
(a.) To injure by drawing, stretching, or the exertion of force; as, the gale strained the timbers of the ship.
(a.) To injure in the muscles or joints by causing to make too strong an effort; to harm by overexertion; to sprain; as, to strain a horse by overloading; to strain the wrist; to strain a muscle.
(a.) To squeeze; to press closely.
(a.) To make uneasy or unnatural; to produce with apparent effort; to force; to constrain.
(a.) To urge with importunity; to press; as, to strain a petition or invitation.
(a.) To press, or cause to pass, through a strainer, as through a screen, a cloth, or some porous substance; to purify, or separate from extraneous or solid matter, by filtration; to filter; as, to strain milk through cloth.
(v. i.) To make violent efforts.
(v. i.) To percolate; to be filtered; as, water straining through a sandy soil.
(n.) The act of straining, or the state of being strained.
(n.) A violent effort; an excessive and hurtful exertion or tension, as of the muscles; as, he lifted the weight with a strain; the strain upon a ship's rigging in a gale; also, the hurt or injury resulting; a sprain.
(n.) A change of form or dimensions of a solid or liquid mass, produced by a stress.
(n.) A portion of music divided off by a double bar; a complete musical period or sentence; a movement, or any rounded subdivision of a movement.
(n.) Any sustained note or movement; a song; a distinct portion of an ode or other poem; also, the pervading note, or burden, of a song, poem, oration, book, etc.; theme; motive; manner; style; also, a course of action or conduct; as, he spoke in a noble strain; there was a strain of woe in his story; a strain of trickery appears in his career.
(1) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(2) None of the strains was found to be positive for cytotoxic enterotoxin in the GM1-ELISA.
(3) They are going to all destinations.” Supplies are running thin and aftershocks have strained nerves in the city.
(4) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(5) We were able to detect genetic recombination between vaccine strains of PRV following in vitro or in vivo coinoculation of 2 strains of PRV.
(6) All of the strains examined were motile and hemolytic and produced lipase and liquid gelatin.
(7) The taxonomic relationship of strains H4-14 and 25a with previously described Xanthobacter strains was studied by numerical classification.
(8) Whereas strain Ga-1 was practically avirulent for mice, strain KL-1 produced death by 21 days in 50% of the mice inoculated.
(9) These results suggest that the pelvic floor is affected by progressive denervation but descent during straining tends to decrease with advancing age.
(10) We also show that the gene of the main capsid protein is expressed from its own promoter in an Escherichia coli strain.
(11) Sequence variation in the gp116 component of cytomegalovirus envelope glycoprotein B was examined in 11 clinical strains and compared with variation in gp55.
(12) By hybridization studies, three plasmids in two forms (open circular and supercoiled) were detected in the strain A24.
(13) In addition, the fact that microheterogeneity may occur without limit in the mannans of the strains suggests that antibodies with unlimited diverse specificities are produced directed against these antigenic varieties as well.
(14) Strains isolated from the environment and staff were not implicated.
(15) The compressive strength of bone is proportional to the square of the apparent density and to the strain rate raised to the 0.06 power.
(16) Escherichia enterotoxigenic strains, Yersinia enterocolitica and Salmonella typhimurium virulent strains, Campylobacter jejuni clinical isolates possess more pronounced capacity for adhesion to enteric cells of Peyer's plaques than to other types of epithelial cells, which may be of importance in the pathogenesis of these infections.
(17) These sequences are also conserved in the same arrangement in minor sequence classes of minicircles from this strain.
(18) The isoelectric points (pI) of E1 and E2 for all VEE strains studied were approx.
(19) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(20) In these bitches, a strain of E coli identical to the strain in the infected uterus was isolated.