(v. t.) To make heavy or heavier; to add to; to increase.
(v. t.) To make worse, or more severe; to render less tolerable or less excusable; to make more offensive; to enhance; to intensify.
(v. t.) To give coloring to in description; to exaggerate; as, to aggravate circumstances.
(v. t.) To exasperate; to provoke; to irritate.
Example Sentences:
(1) The major acute postoperative finding was aggravation of preexisting pharyngeal dysfunction.
(2) The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system.
(3) This experimental study shows that vitamin A in high doses has an adjuvant effect, that is aggravating considerably the immunologic arthritis induced in the Wistar rat.
(4) Nine factors have been isolated whose varying combinations were most contributory to the risk of the development of CS in the studied population: cardiac diseases, transient disorder of the cerebral circulation, arterial hypertension, atherosclerosis, aggravated heredity for cardiovascular diseases, intermittent claudication, diabetes mellitus, systematic alcohol abuse, and hypodynamia.
(5) A 63-year-old man, with a Waldenström's disease discovered by cryoglobulinemia (ischemic lesions of fingers) was quickly aggravating (hyperviscosity syndrome) under treatment by chlorambucil in a dosage of 8 mg daily.
(6) Existing visual field defects in three patients were slightly aggravated and in four patients, with a pathological optic disc, visual field loss developed.
(7) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
(8) As a result of a psychopathological total systems analysis of the debut of exogenously aggravated and nonaggravated paranoid schizophrenia the authors have revealed a significant interrelationship allowing the characterization of both general regularities of the "background" effect and individual characteristics secondary to a concrete nature of exogenous impact.
(9) Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
(10) Uncontrolled diabetes mellitus can aggravate the hyperlipidaemia associated with this disorder, presumably by increasing triglyceride synthesis and reducing very low density lipoprotein catabolism by lipoprotein lipase.
(11) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(12) A definite correlation was established between the disease and the character of work and specificity of the working postures: a long stay in a bent position aggravated by the pressure of the apron strap weighing 8-10 kg on the lumbar part of the spine.
(13) Empirical studies suggest the following main conclusions: functional somatic symptoms are extremely common; a large proportion appear to be caused by physiologic activity and tend to be aggravated by emotion.
(14) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(15) This situation can lead to an aggravation of degenerative complications.
(16) He believes there are several factors that could aggravate extremists, other than the videos.
(17) Direct relationship between the increase of blood fibrinolytic activity and the aggravation of the vascular degeneration could not be observed in this experiment.
(18) Wash-out experiments show that the sugars prevent the aggravation of mediator release by a binding of sugar to the basophil cell membrane, thereby causing a blockade of binding sites responsible for the potentiating effect of virus.
(19) We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuclear leukocyte oxidants or hydrogen peroxide (H2O2).
(20) However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Wane
Definition:
(v. i.) To be diminished; to decrease; -- contrasted with wax, and especially applied to the illuminated part of the moon.
(v. i.) To decline; to fail; to sink.
(v. t.) To cause to decrease.
(n.) The decrease of the illuminated part of the moon to the eye of a spectator.
(1) These were not observed in area 5, although here the distribution of callosal neurons waxed and waned in the tangential cortical plane.
(2) Follow-up results from 10 controlled trials are consistent with waning of BCG protective efficacy with time since vaccination.
(3) Pharmacists are criticized for a failing sense of mission and a waning dependence on knowledge.
(4) The acquired immunodeficiency syndrome (AIDS) epidemic shows no sign of waning.
(5) Ferguson’s influence at Old Trafford has clearly waned since the Moyes appointment but, notably, there is no admission on his part that he chose the wrong man, insisting that the club followed a rigorous and methodical selection process.
(6) The wane in US power over the country it invaded eight years ago, coupled with a return to political prominence for Sadrists, seems to have been enough to lure Sadr back to Najaf, which he fled in 2004 after it was surrounded by US troops.
(7) Pretreatment with cyclophosphamide caused a delay in the development and waning of reactivity.
(8) Since then of course his popularity has waned, his net satisfaction rating is now negative.” The latest Newspoll has Labor ahead by two percentage points in two-party preferred terms (49% to 51%).
(9) It is suggested that the response of prenatally stimulated animals had waned before birth.
(10) After rising employment has failed to lift output as far as hoped, this reflects waning hopes about the potential of the UK economy once restored to full pelt.
(11) IL-2 production in soluble egg Ag-stimulated spleen cells of mice was detectable at 6, peaked at 8 and waned by 20 wk of the infection.
(12) High concentrations of cobratoxin depressed indirect twitches and endplate potentials (e.p.ps) without inducing waning of contractilities or run-down of trains of e.p.ps evoked at 10-100 Hz.
(13) The level of antigranulocyte antibody in the serum often begins to wane prior to improvement in the ANC and can give an indication of when recovery will begin to occur.
(14) We have already seen in this World Cup that European powers are on the wane.
(15) The effect began to appear in about 20 min after administration, the peak effect was attained in 120 min and later on this waned off completely by 24 h. The effect was similar in young (15 days) and in adult (70 days) rats.
(16) It is provisionally suggested that enhancement of the perseveration represents an innate response to stressful stimuli, but as animals learn mastery over the response contingencies, the persistence in adopting such a response strategy wanes.
(17) The placebo effect gradually waned, but the response to the active combination was maintained for the duration of the study.
(18) Other evidence is provided by the waning and waxing of gastritis, which has been correlated in several studies with clearance followed by recrudescence of the organisms.
(19) Yet Spurs' interest in Van Gaal has not waned even in light of Sherwood's impressive impact in his first senior management role.
(20) There have been suggestions in recent weeks that the US support for the Syrian non-extremist opposition is waning, and the US has reluctantly concluded that unwavering Russian support for Assad means the only way to oust Isis is by making cause with Russia and Assad.