(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.
Gon
Definition:
() of Gin
() imp. & p. p. of Go.
Example Sentences:
(1) The classic Jedi response to subservience can be seen in the contrast between Luke’s first meeting with C-3PO – “I see, Sir”; “You can call me Luke”; “I see, Sir Luke,”; “No, just Luke” – and Qui-Gon Jinn meeting Jar Jar Binks: “Mesa your humble servant”; “That won’t be necessary”.
(2) The description of the peripheral course of the greater occipital nerve (GON) varies in the literature.
(3) On the bench are four judges, with Korean Judge O-Gon Kwon presiding.
(4) Such headaches could be arrested by injecting the ipsilateral greater occipital nerve (GON) with local anaesthetic, prevented for up to 4 weeks by injecting 'Depomedrol' into the region of the nerve and for several months by surgical division of the nerve.
(5) I didn’t actually come here to free slaves,” says Liam Neeson as Jedi Master Qui-Gon Jinn in The Phantom Menace , like a person to whom a huge number of vexing tasks has been subcontracted.
(6) The presiding ICTY judge delivering the ruling, O-Gon Kwon, cleared Karadžić of one charge: responsibility for genocide in attacks on other towns and villages where Croats and Bosnians were driven out.
(7) It's about time for him to stand up and just go real black for one interview and say, 'If you keep fucking with me, we gon' have problems.'"
(8) It is shown that the method of minimising the perimeter of the polygon obtained by connecting the centromeres is only applicable if the positions of the n centromeres do not deviate too much from an arrangement along a regular n-gon.
(9) The presiding judge, O-Gon Kwon, adjourning the hearing, said the judges would rule later this week on whether to impose a counsel on Karadzic and on whether he should be compelled to attend.
(10) The avidin-biotin peroxidase complex immunostaining method combined with the glucose oxidase-nickel (ABC-GON) technique was applied to the guinea pig cochlea and middle ear, the fine structure of CGRP-containing fibers in the organ of Corti was also observed.
(11) The distribution confirms our earlier proposal that four trimers of polypeptide IX are embedded in the large cavities in the upper surface of the GON to cement hexons into a highly-stable assembly.
(12) The trapezius muscle was penetrated by the GON in 45% of cases, the semispinal muscle of the head was penetrated in 90% of cases, and the inferior oblique muscle of head was penetrated in 7.5% of cases.
(13) Her mother, my big momma, said, 'No way, you ain't gon' go, they gon' bomb it.'
(14) To examine the release of insulin in response to oral glucose, intravenous glucagon and intravenous arginine, we measured the levels of plasma glucose, immuno-reactive insulin (IRI) and C-peptide levels on fasting and following an oral glucose loading (OGTT), intravenous glucagon (GON) and arginine (ARG) infusion test in nine newly diagnosed non-insulin dependent diabetics.
(15) Calcium alginate-entrapped mycelium of Penicillium raistrickii i 477 was used for the 15 alpha-hydroxylation of 13-ethyl-gon-4-ene-3,17-dione.
(16) Presiding judge Oh-Gon Kwon said prosecutors did not provide enough evidence to "be capable of supporting a conviction of genocide in the [Bosnian] municipalities".
(17) The location of a minor component (6%) of the GON has been determined using a novel combination of electron microscopy and X-ray crystallography.
(18) The isolation of chlamydial trachomatis in sera of patients with gon ococcal urethritis (GU), non-gonococcal urethritis (NGU), post-gonococca l urethritis (PGU) and trachomainclusion conjunctivitis (TRIC) is discussed.
(19) The Brookhaven Scanning Transmission Electron Microscope (STEM) was used to estimate the distribution of protein in the GON to a resolution of 15-18 A.
(20) Entrapment of the greater occipital nerve (GON) in its peripheral course has been thought to be of possible pathogenic significance in cervicogenic headache.