(1) "The new feminine ideal is of egg-smooth perfection from hairline to toes," she writes, describing the exquisite agony of having her fingers, arms, back, buttocks and nostrils waxed.
(2) It has been awfully hard-won, carved slowly out of a big block of human agony.
(3) Her agony and her rapture stay interior, and they flip-flop like nerves in this beautiful, grave black-and-white movie.
(4) Those who remember the Two Davids of the 1987 SDP-Liberal Alliance will recall the exquisite agony only too well, cruelly captured by the Spitting Image puppet of little Steel perched in big Owen's pocket.
(5) Using male and female Wistar rats, pituitary response to cardiac and respiratory failure type (CFT and RFT) sudden death caused by the intravenous administration of KC1 and SCC, respectively, was examined by analyzing variation in pituitary immunoreactive beta-endorphin (IR-beta-EP) levels determined by radioimmunoassay after death and in circulating IR-beta-EP levels during periods of agony.
(6) I was in the surgical ward at Westmorland General Hospital on Kendal Green, and it was agony.
(7) I'd go after work and he'd paint till 1 or 1.30 in the morning, and it was agony lying there on the floor.
(8) Evidently fuelled by the agony of losing a series twelve months ago when the trophy was almost within their grasp, they also had the teamwork, technique and experience to turn their quest for revenge into a reality.
(9) Facebook Twitter Pinterest Even those who’ve never seen a downhill ski race couldn’t help but sympathise with Bode Miller’s agony at missing out on a medal in what will surely be the last Olympic event of his career.
(10) "When the disaster was big enough," King writes, "agony and violent death had an enriching quality."
(11) Even at UCH, when no one was there for us and my father, having not slept for almost 30 hours, was pulling his hair out in agony, I tried to look at it all as a kind of comedy of errors."
(12) They were subject, of course, to the prison censor, but the agony over Winnie, and the passion of which that agony was a product, blazes through them.
(13) That he ended up in the dock in The Hague at all surprised many who have studied the man and his country's agony through the 1990s.
(14) Shawcross, however, maintains there was no bad intent and said for that reason he has not been tormenting himself about the moment he collided with Ramsey's right leg and left the teenager writhing in agony.
(15) He notes the uneven agony - 80% will land in developing countries.
(16) The poor animals are thrown back into the water to die in agony, a practice condemned by environmental campaigners.
(17) The rest was pure agony for the Australians, give or take a yellow card for Sonny Bill Williams, given for a dangerous tackle.
(18) The woman before you in agony pushing and pushing, losing all dignity, does not care one bit whether I am feeling alarmed at her screaming, worried about where I should be standing, wondering whether I should rub her back or try and make small talk between contractions.
(19) Litvinenko sipped “three or four times” from a cup of radioactive tea, and died in agony 23 days later, the inquiry heard last week.
(20) Our most excruciating agony is of not being noticed in the world.
Agonize
Definition:
(v. i.) To writhe with agony; to suffer violent anguish.
(v. i.) To struggle; to wrestle; to strive desperately.
(v. t.) To cause to suffer agony; to subject to extreme pain; to torture.
Example Sentences:
(1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
(3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
(4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
(5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
(6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
(7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
(8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
(9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
(10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
(11) In the inferior parietal cortex, agonal status confounded this comparison.
(12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
(13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
(14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
(15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
(16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
(17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
(18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
(19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
(20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.