(n.) One who contends for the prize in public games.
Example Sentences:
(1) alpha 1-Adrenergic agonists, phenylephrine and norfenefrine, did not affect the synthesis.
(2) Data obtained with fenoldopam were corroborated with use of SK&F 38393, another dopamine D1-receptor agonist.
(3) The GABA receptor agonist progabide reduced VCMs and locomotor activity.
(4) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(5) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
(6) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(7) The binding to DNA-cellulose of heat-activated [3H]RU486-receptor complexes was slightly decreased (37%) when compared with that of the agonist [3H]R5020-receptor complexes (47%).
(8) These later results suggest that dopamine agonists increase sensorimotor reactivity measured with acoustic startle by acting on sensory rather than motor parts of the reflex arc.
(9) Only methoxyindole acetic acid was detectable after incubation of unstimulated and alpha-adrenergic-agonist-treated pineal glands.
(10) It inhibits platelet and vascular smooth muscle activation by cGMP-dependent attenuation of the agonist-induced rise of intracellular free Ca2+.
(11) The elimination half-life of most beta-agonists is relatively short, and pharmacokinetics are independent of dose and duration of treatment.
(12) Substance P (SP), a relatively non-selective tachykinin receptor agonist, and Septide and Senktide, highly selective NK-1 and NK-3 tachykinin receptor agonists, respectively, were injected intradermally in rats.
(13) Responses of control tissues to an alpha agonist (norepinephrine) were increased at lower temperatures and responses to a beta agonist (isoprenaline) were increased at higher temperatures.
(14) The inhibition of all three agonist responses by 1.1 mM calcium was competitive.
(15) The alpha 2 agonist, clonidine, produced a larger dose-related increase in food intake in lean rats than in the fatty rats.
(16) This stimulation is mediated by one receptor with an apparent affinity of 3.3 X 10(-6) M. The hydroxyl group in the para position on phenylethanolamine was absolutely necessary to obtain an agonist whereas the meta hydroxyl group or the presence of a catechol almost suppressed the activity.
(17) The alpha 2-adrenoceptor agonist clonidine is most potent for stimulating Isc.
(18) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(19) We have characterized the effects of adenosine, the A1-receptor agonist N6-(L-2-phenylisopropyl)-adenosine (PIA) and the A2-receptor agonist 5'-(N-ethyl)-carboxamido-adenosine (NECA), in isolated human pulmonary vessels.
(20) Long-term treatment with agents that stimulate the beta-receptor (prenalterol and pirbuterol) has not proved to be useful in the treatment of chronic heart failure; moreover, prolonged treatment with beta-agonists (dobutamine and pirbuterol) may adversely affect survival.
Protagonist
Definition:
(n.) One who takes the leading part in a drama; hence, one who takes lead in some great scene, enterprise, conflict, or the like.
Example Sentences:
(1) The Independent noted that one of the female protagonists yelled "You c***!"
(2) There are numerous other male protagonists out there in desperate need of a sex change.
(3) At times, they gained a momentum that took even the protagonists by surprise.
(4) Phase II is the attack and destruction of the allograft by these protagonists.
(5) Not relegate them to background characters in the service of a white cis-male fictional protagonist.” Both groups have drawn their conclusions from the film’s trailer.
(6) But the bedeviled foray also works as a potent allegory on the slow, vice-like workings of conscience, as guilt hunts down the protagonists with the shrieking remorselessness of Greek furies.
(7) We don’t need a man to help us or lead us … We’re protagonists who defend a Podemos for everyone.” Iglesias responded coolly, saying he was convinced there would be “far better candidates”.
(8) Owing to the poor quality of much of this research the claims of the protagonists of these therapies cannot be proved or disproved.
(9) The roles of each protagonist are related in detail, with pragmatism.
(10) In 90 engrossing minutes came comedy, controversy, drama, breathtaking moments and an eye-catching turn from the star protagonist himself.
(11) The novelist and critic Tom Bissell has described the protagonist's Jewish lawyer in 2002's Vice City as "an anti-Semitic parody of an anti-Semitic parody", while in the new game one of the main character's daughters has a tattoo that reads "skank", and one mission involves you helping a paparazzo capture a starlet's "low-hanging muff".
(12) "But where in Dostoevsky or Poe the protagonist experiences his double as a terrifying embodiment of his own otherness (and especially his own voraciousness and destructiveness), we barely notice the difference between ourselves and our online double.
(13) Despite the world-weary tone of a brutal review in the New York Times, which suggested that it added nothing new to the "groaning shelf" of homosexual literature, a story with an unashamedly gay protagonist unleashed a storm of protest in a country where sodomy was still illegal.
(14) It was probably all over for the idea of being stoned as a portal to a higher consciousness after the release of a film in which the two perma-baked protagonists drive a car with the numberplate MUF DVR.
(15) M∆tilda – spelt with an Alt-J – references Luc Besson's film Léon and is "fuelled by the shared demise of both the protagonist and antagonist".
(16) Protagonists of the method included Ambroise Paré, Thomas Fienus, Hieronymus Fabricius ab Aquapendente, Julius Casserius, and Johannes Scultetus.
(17) Facebook Twitter Pinterest Gone Girl star Ben Affleck: ‘Usually the protagonist is full of shit’ - video interview Fincher’s film narrowly beat another new film, the horror prequel Annabelle , into second place.
(18) But the protagonists – Patty especially – are constantly making new discoveries about themselves: redemptive insights, lessons in the contradictoriness of the human heart.
(19) Writing about her novel, Wolf Hall, Hilary Mantel has explained how she brought the protagonist Thomas Cromwell alive for the reader by giving him vivid memories.
(20) Another way of assessing the claim and counterclaim is to consider the characters of the protagonists.