What's the difference between agonize and smart?

Agonize


Definition:

  • (v. i.) To writhe with agony; to suffer violent anguish.
  • (v. i.) To struggle; to wrestle; to strive desperately.
  • (v. t.) To cause to suffer agony; to subject to extreme pain; to torture.

Example Sentences:

  • (1) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
  • (2) Under conditions of 5-HT1-like, 5-HT2 and 5-HT3 receptor blockade, the following rank order of agonism was observed: 5-HT > 5-methoxytryptamine = renzapride > (S)-zacopride > (R,S-zacopride > 5-carboxamidotryptamine > BRL 24682 > (R-zacopride > metoclopramide > 2-methyl-5-HT > sulpiride.
  • (3) At the agonal stage, the isoproterenol dose-response curve was shifted significantly to the right in myocardial membranes from endotoxic rats, but there was no significant decrease in maximum stimulated activity.
  • (4) Agonal state effects the stability of brain compounds and causes brain hypoxia.
  • (5) However, further studies showed compounds which exhibited either partial agonism in the RFA and competitive antagonism of 5-HT in the RA, or antagonism of 5-HT in both arteries with different affinities.
  • (6) Catecholamines were detectable in the major neurons, in small intensely fluorescent cells, and in adrenergic fibers with varicosities at levels that varied with the patient's age, cause of death, duration of the agonal period, the treatment administered, and the time when the material had been taken after death.
  • (7) Certain derivatives of the antagonists naloxone and naltrexone showed partial agonism.
  • (8) Except for desGly(NH2)AVP, which is a weak V2 agonist, the remaining desGly and desGly(NH2) analogues of 1-3 exhibit substantial V2 agonism and are thus highly selective V2 agonists.
  • (9) But bureaucratic dysfunction means less than half have been given out – as shown by two state department charts – and only at the end of agonizingly long waiting periods .
  • (10) The results failed to support the female agonism hypothesis and indicate a need for more detailed studies of intermale social dynamics.
  • (11) In the inferior parietal cortex, agonal status confounded this comparison.
  • (12) Dilevalol is a novel antihypertensive agent combining vasodilation due to selective beta 2-adrenergic receptor agonism with nonspecific beta antagonism.
  • (13) The results indicate that alpha 2-adrenergic agonism with clonidine inhibits the bronchoconstriction induced by histamine.
  • (14) We have found no evidence of a physiologically relevant effect of serotonin agonism on osmoregulated vasopressin release, or on the ability of normal man to excrete a water load.
  • (15) The partial agonism of N alpha-guanylhistamine is related to the ability of the drug to bind with the receptor in two different modes with similar affinity.
  • (16) In contrast U50,488H produced biphasic curves characterized by a higher potency phase of agonism that was susceptible to antagonism by 16-methylcyprenorphine (RX8008M) and a lower potency phase that was apparently non-opioid in nature.
  • (17) As this profile of activity is not shared by the shorter-acting compound, salbutamol, it would seem that anti-inflammatory activity is associated with beta-adrenoceptor agonism of long duration.
  • (18) To clarify the regulation of duodenal motility, the aim of the present study was to investigate the effects of alpha-adrenoceptor agonism and blockade and of galanin on duodenal motility.
  • (19) Agonist-independent pA2 estimates for ICS 205-930 (6.3-6.6) suggest a single site of agonism.
  • (20) In addition, analyses of beta-adrenoceptor agonism and antagonism, using selective (beta 1: T-1583, beta 2: procaterol) and non-selective (isoproterenol) agonists as well as selective (beta 1: atenolol, beta 2: ICI 118,551) and non-selective (propranolol) antagonists, confirmed that beta-adrenoceptors in the canine facial vein are not homogeneous, with the beta 1-subtype predominating over the beta 2-subtype, and that the canine saphenous vein has a homogeneous population of the beta 2-subtype, as reported in the other species.

Smart


Definition:

  • (v. i.) To feel a lively, pungent local pain; -- said of some part of the body as the seat of irritation; as, my finger smarts; these wounds smart.
  • (v. i.) To feel a pungent pain of mind; to feel sharp pain or grief; to suffer; to feel the sting of evil.
  • (v. t.) To cause a smart in.
  • (v. i.) Quick, pungent, lively pain; a pricking local pain, as the pain from puncture by nettles.
  • (v. i.) Severe, pungent pain of mind; pungent grief; as, the smart of affliction.
  • (v. i.) A fellow who affects smartness, briskness, and vivacity; a dandy.
  • (v. i.) Smart money (see below).
  • (v. i.) Causing a smart; pungent; pricking; as, a smart stroke or taste.
  • (v. i.) Keen; severe; poignant; as, smart pain.
  • (v. i.) Vigorous; sharp; severe.
  • (v. i.) Accomplishing, or able to accomplish, results quickly; active; sharp; clever.
  • (v. i.) Efficient; vigorous; brilliant.
  • (v. i.) Marked by acuteness or shrewdness; quick in suggestion or reply; vivacious; witty; as, a smart reply; a smart saying.
  • (v. i.) Pretentious; showy; spruce; as, a smart gown.
  • (v. i.) Brisk; fresh; as, a smart breeze.

Example Sentences:

  • (1) Pint from £2.90 The Duke Of York With its smart greige interior, flagstone floor and extensive food menu (not tried), this newcomer feels like a gastropub.
  • (2) Never become so enamored of your own smarts that you stop signing up for life’s hard classes.
  • (3) "He's defined by being himself, by being smart, by being a good athlete," Goldwater said of Keller.
  • (4) Advancing the health and rights of women is the right – and smart – thing to do for any nation hoping to remain or emerge as a leader on the global stage.
  • (5) By way of encouragement we've got 10 copies of Faber's smart new anniversary edition to give away.
  • (6) It’s likely Xi’s brand of smart authoritarianism will keep not just his party in power but the whole show on the road If all this were to succeed as intended, western liberal democratic capitalism would have a formidable ideological competitor with worldwide appeal, especially in the developing world.
  • (7) These letters are also written during a period when Joyce was still smarting from the publishing difficulties of his earlier works Dubliners and A Portrait of the Artist as a Young Man.” Gordon Bowker, Joyce’s biographer, agreed: “Joyce’s problem with the UK printers related to the fact that here in those days printers were as much at risk of prosecution on charges of publishing obscenities as were publishers, and would simply refuse to print them.
  • (8) I could just banish the app from my phone forever, but deleting a piece of smart tech that makes my life easier doesn’t feel very satisfying.
  • (9) I buy ‘smart price’, own-brand cornflakes, rather than Kellogg’s, and I still get to the checkout and think, ‘That’s come to a lot again.’” Are you Daniel Blake?
  • (10) If you're sincere and smart and genuine and lovable that's what's going to come across in your videos and tweets."
  • (11) In a statement, Fisher Price said: “We recently learned of a security vulnerability with our Fisher-Price WiFi-connected Smart Toy Bear.
  • (12) Can consoles still survive in a rapidly changing business where smartphones, tablets and smart TVs, and now Steam Machines, are threatening?
  • (13) Snapchat is also thinking about new devices, launching a Snapchat Micro app for Samsung's Galaxy Gear smart watch in September, capable of shooting pics and videos with the device's camera, then sharing them.
  • (14) There were signs of encouragement early in the second half from Sunderland, and they should have pulled one back only for a terrible call from the assistant referee Eddie Smart.
  • (15) In Drosophila melanogaster new tester strains for the somatic mutation and recombination test (SMART) in the wing were constructed with the aim of increasing the metabolic capacity to activate promutagens.
  • (16) And there are plenty who think that, as our libel laws are cleaned up, smart lawyers are switching horses to privacy.
  • (17) I think the heart of good comedy really lives in truth and reacting to the absurdities, hypocrisies, abuses of power in the world.” Late night television is a no longer a glass of warm milk before bed, it’s a lunch buffet And as TV viewership declines and internet virality becomes as important as real-time eyeballs, cable networks might find that topical comedy is a smart, cost-effective way to grab cross-platform attention.
  • (18) With cities moving markets, joint procurement standards generate great potential for economies of scale, from buses to smart street lighting.
  • (19) A smart city would use IT to manage traffic so air stays fit to breathe.
  • (20) Pitched as a "smart" calendar, it's easy to create appointments and events, and ties in neatly with the developer's separate Any.do to-do lists app.